A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS. (Q35626397)

9 August 2017

title

A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS. (English)

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Lyn H Jones

12

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author name string

Hua Xu

1

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Erik C Hett

2

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Ariamala Gopalsamy

3

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Mihir D Parikh

4

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Kieran F Geoghegan

5

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Robert E Kyne

6

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Carol A Menard

7

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Arjun Narayanan

8

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Ralph P Robinson

9

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Douglas S Johnson

10

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Michael A Tones

11

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publication date

11 May 2015

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volume

11

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issue

10

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page(s)

2709-2712

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"Minimalist" cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling

9 August 2017

cites work

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Double-modification of lectin using two distinct chemistries for fluorescent ratiometric sensing and imaging saccharides in test tube or in cell.

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Sulfonyl fluorides as privileged warheads in chemical biology

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Proteomic profiling of metalloprotease activities with cocktails of active-site probes

21 January 2018

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Decapping Scavenger (DcpS) enzyme: advances in its structure, activity and roles in the cap-dependent mRNA metabolism.

21 January 2018

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DcpS as a therapeutic target for spinal muscular atrophy

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Genetic mapping of chronic childhood-onset spinal muscular atrophy to chromosome 5q11.2-13.3

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The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models

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The DcpS inhibitor RG3039 improves motor function in SMA mice.

21 January 2018

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Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity

21 January 2018

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Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides

21 January 2018

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A stepwise huisgen cycloaddition process: copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes

21 January 2018

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Benzophenone photoprobes for phosphoinositides, peptides and drugs

21 January 2018

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Rational Targeting of Active-Site Tyrosine Residues Using Sulfonyl Fluoride Probes

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21 January 2018

Identifiers

DOI

10.1039/C5MB00288E

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9 August 2017

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