Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide (Q35620922)

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scientific article published on August 1999

Language	Label	Description	Also known as
English	Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide	scientific article published on August 1999

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Crigler-Najjar syndrome

1 reference

based on heuristic

inferred from title

author name string

B T Kren

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

B Parashar

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

P Bandyopadhyay

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

N R Chowdhury

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

J R Chowdhury

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

C J Steer

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

0 references

publication date

1 August 1999

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PubMed publication ID

9 August 2017

96

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

18

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

10349-10354

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Gene repair using chimeric RNA/DNA oligonucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17891

27 July 2018

Targeted gene repair directed by the chimeric RNA/DNA oligonucleotide in a mammalian cell-free extract

1 reference

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Failure to achieve gene conversion with chimeric circular oligonucleotides: potentially misleading PCR artifacts observed

1 reference

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Different frequency of gene targeting events by the RNA-DNA oligonucleotide among epithelial cells

1 reference

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Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide

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Isolation of MutSbeta from human cells and comparison of the mismatch repair specificities of MutSbeta and MutSalpha

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RecA-mediated joint molecule formation between O-methylated RNA/DNA hairpins and single-stranded targets

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Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation

1 reference

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Therapeutic gene targeting

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Functional overlap in mismatch repair by human MSH3 and MSH6.

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Strand-specific mismatch repair in mammalian cells

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Long term correction of bilirubin-UDP-glucuronosyltransferase deficiency in Gunn rats by administration of a recombinant adenovirus during the neonatal period

1 reference

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Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide

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Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium

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Mismatch repair: mechanisms and relationship to cancer susceptibility

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Bilirubin UDP-glucuronosyltransferase 1 is the only relevant bilirubin glucuronidating isoform in man

1 reference

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Analysis of bilirubin and bilirubin mono- and di-conjugates. Determination of their relative amounts in biological samples

1 reference

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Isolation of multiple normal and functionally defective forms of uridine diphosphate-glucuronosyltransferase from inbred Gunn rats

1 reference

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27 July 2018

The 3-methylcholanthrene-inducible UDP-glucuronosyltransferase deficiency in the hyperbilirubinemic rat (Gunn rat) is caused by a -1 frameshift mutation

1 reference

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Specific incorporation of asialofetuin-labeled liposomes into hepatocytes through the action of galactose-binding protein.

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Molecular basis for the lack of bilirubin-specific and 3-methylcholanthrene-inducible UDP-glucuronosyltransferase activities in Gunn rats. The two isoforms are encoded by distinct mRNA species that share an identical single base deletion

1 reference

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Unconjugated Bilirubin and an Increased Proportion of Bilirubin Monoconjugates in the Bile of Patients with Gilbert's Syndrome and Crigler-Najjar Disease

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Gene therapy with bilirubin-UDP-glucuronosyltransferase in the Gunn rat model of Crigler-Najjar syndrome type 1.

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Complete correction of hyperbilirubinemia in the Gunn rat model of Crigler-Najjar syndrome type I following transient in vivo adenovirus-mediated expression of human bilirubin UDP-glucuronosyltransferase

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Identifiers

10.1073/PNAS.96.18.10349

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1999PNAS...9610349K

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

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