The SWI/SNF complex--chromatin and cancer. (Q35667471)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14964309%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

review article

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title

The SWI/SNF complex--chromatin and cancer (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14964309%20AND%20SRC:MED&resulttype=core&format=json

23 November 2019

1

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23 November 2019

author name string

Stuart H Orkin

series ordinal

2

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23 November 2019

language of work or name

English

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publication date

1 February 2004

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23 November 2019

published in

Nature Reviews Cancer

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23 November 2019

volume

4

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23 November 2019

issue

2

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23 November 2019

page(s)

133-142

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Histone acetylation and chromatin remodeling: which comes first?

23 November 2019

cites work

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Chromatin remodeling, histone modifications, and DNA methylation-how does it all fit together?

31 March 2020

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Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection

31 March 2020

1 reference

Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae

31 March 2020

1 reference

Dissecting the regulatory circuitry of a eukaryotic genome

31 March 2020

1 reference

Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits

31 March 2020

1 reference

A model for chromatin remodeling by the SWI/SNF family

31 March 2020

1 reference

Human SWI/SNF interconverts a nucleosome between its base state and a stable remodeled state

31 March 2020

1 reference

SWI/SNF unwraps, slides, and rewraps the nucleosome

31 March 2020

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ATP-dependent chromatin-remodeling complexes.

31 March 2020

1 reference

A role for the yeast SWI/SNF complex in DNA replication

31 March 2020

1 reference

Ca2+/calmodulin binds to and modulates P/Q-type calcium channels

31 March 2020

1 reference

Inhibition of HIV-1 virion production by a transdominant mutant of integrase interactor 1.

31 March 2020

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Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5

31 March 2020

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Global role for chromatin remodeling enzymes in mitotic gene expression

31 March 2020

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Constitutional mutations of the hSNF5/INI1 gene predispose to a variety of cancers

31 March 2020

1 reference

Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer

31 March 2020

1 reference

Central nervous system atypical teratoid/rhabdoid tumors of infancy and childhood

31 March 2020

1 reference

Germline INI1 mutation in a patient with a central nervous system atypical teratoid tumor and renal rhabdoid tumor

31 March 2020

1 reference

Mutations of the hSNF5/INI1 Gene in Renal Rhabdoid Tumors With Second Primary Brain Tumors

31 March 2020

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Familial posterior fossa brain tumors of infancy secondary to germline mutation of the hSNF5 gene

31 March 2020

1 reference

Spectrum of hSNF5/INI1 somatic mutations in human cancer and genotype-phenotype correlations

31 March 2020

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INI1 mutations in meningiomas at a potential hotspot in exon 9

31 March 2020

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Aberrations of the hSNF5/INI1 gene are restricted to malignant rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric solid tumors

31 March 2020

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Ultrastructure of malignant rhabdoid tumor of the kidney. A distinctive renal tumor of children

31 March 2020

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Haploinsufficiency of Snf5 (integrase interactor 1) predisposes to malignant rhabdoid tumors in mice

31 March 2020

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The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression

31 March 2020

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Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice

31 March 2020

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Highly penetrant, rapid tumorigenesis through conditional inversion of the tumor suppressor gene Snf5

31 March 2020

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Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

31 March 2020

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Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

31 March 2020

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A key role of the hSNF5/INI1 tumour suppressor in the control of the G1-S transition of the cell cycle

31 March 2020

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Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.

31 March 2020

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P16INK4a is required for hSNF5 chromatin remodeler-induced cellular senescence in malignant rhabdoid tumor cells

31 March 2020

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The yeast SNF2/SWI2 protein has DNA-stimulated ATPase activity required for transcriptional activation

31 March 2020

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The Drosophila snr1 and brm proteins are related to yeast SWI/SNF proteins and are components of a large protein complex

31 March 2020

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Identification and characterization of Drosophila relatives of the yeast transcriptional activator SNF2/SWI2.

31 March 2020

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brg1: a putative murine homologue of the Drosophila brahma gene, a homeotic gene regulator

31 March 2020

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A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor

31 March 2020

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BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription

31 March 2020

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Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor

31 March 2020

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Characterization of SWI/SNF protein expression in human breast cancer cell lines and other malignancies

31 March 2020

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A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes

31 March 2020

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Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).

31 March 2020

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The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

31 March 2020

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BRG-1 is required for RB-mediated cell cycle arrest

31 March 2020

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Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF

31 March 2020

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RB and hbrm cooperate to repress the activation functions of E2F1

31 March 2020

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Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

31 March 2020

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BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer

31 March 2020

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The Fanconi anaemia/BRCA pathway

31 March 2020

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BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformation

31 March 2020

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c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function

31 March 2020

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ORC1 interacts with c-Myc to inhibit E-box-dependent transcription by abrogating c-Myc-SNF5/INI1 interaction

31 March 2020

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The C-terminal SET domains of ALL-1 and TRITHORAX interact with the INI1 and SNR1 proteins, components of the SWI/SNF complex

31 March 2020

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Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner

31 March 2020

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The MLL fusion partner AF10 binds GAS41, a protein that interacts with the human SWI/SNF complex

31 March 2020

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Leukemic HRX fusion proteins inhibit GADD34-induced apoptosis and associate with the GADD34 and hSNF5/INI1 proteins

31 March 2020

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ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

31 March 2020

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Human SWI-SNF component BRG1 represses transcription of the c-fos gene

31 March 2020

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The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation

31 March 2020

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Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes

31 March 2020

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The BRG-1 subunit of the SWI/SNF complex regulates CD44 expression

31 March 2020

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Functional selectivity of recombinant mammalian SWI/SNF subunits

31 March 2020

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SWI/SNF chromatin remodeling and cancer

31 March 2020

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The Swi/Snf family nucleosome-remodeling complexes and transcriptional control

31 March 2020

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Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure

31 March 2020

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7 January 2021

Mutational analysis of INI1 in sporadic human brain tumors

1 reference

7 January 2021

Atypical teratoid/rhabdoid tumors and choroid plexus tumors: when genetics "surprise" pathology.

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7 January 2021

Oncogenic role of "master" transcription factors in human leukemias and sarcomas: a developmental model

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7 January 2021