Genetic analysis of basophil function in vivo. (Q35731933)

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31 January 2020

title

Genetic analysis of basophil function in vivo (English)

1 reference

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31 January 2020

author

Christopher D C Allen

7

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31 January 2020

author name string

Brandon M Sullivan

1

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31 January 2020

Hong-Erh Liang

2

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31 January 2020

Jennifer K Bando

3

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31 January 2020

Davina Wu

4

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31 January 2020

Laurence E Cheng

5

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31 January 2020

James K McKerrow

6

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31 January 2020

Richard M Locksley

8

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31 January 2020

language of work or name

English

0 references

publication date

8 May 2011

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31 January 2020

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31 January 2020

volume

12

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31 January 2020

issue

6

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31 January 2020

page(s)

527-535

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Basophils are the major producers of IL-4 during primary helminth infection

31 January 2020

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12 July 2018

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Inflammatory dendritic cells--not basophils--are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen

12 July 2018

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Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks

12 July 2018

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12 July 2018

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The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.

12 July 2018

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12 July 2018

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Cutting edge: basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3.

12 July 2018

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12 July 2018

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Efficient generation of long-distance conditional alleles using recombineering and a dual selection strategy in replicate plates

12 July 2018

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Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response

12 July 2018

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MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.

12 July 2018

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Cytokine-secreting follicular T cells shape the antibody repertoire

12 July 2018

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Basophils: a nonredundant contributor to host immunity

12 July 2018

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IL-3 is required for increases in blood basophils in nematode infection in mice and can enhance IgE-dependent IL-4 production by basophils in vitro

12 July 2018

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Basophil effector function and homeostasis during helminth infection

12 July 2018

1 reference

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T cell-derived IL-3 plays key role in parasite infection-induced basophil production but is dispensable for in vivo basophil survival.

12 July 2018

1 reference

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Homeostasis and effector function of lymphopenia-induced "memory-like" T cells in constitutively T cell-depleted mice

12 July 2018

1 reference

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A mechanism for the initiation of allergen-induced T helper type 2 responses

12 July 2018

1 reference

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Single-cell dynamics of T-cell priming

12 July 2018

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Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis

12 July 2018

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Rapid lineage-specific diversification of the mast cell chymase locus during mammalian evolution

12 July 2018

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Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system

12 July 2018

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Ciliary beat frequency is maintained at a maximal rate in the small airways of mouse lung slices

12 July 2018

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A two-step process for cytokine production revealed by IL-4 dual-reporter mice

12 July 2018

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Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.

12 July 2018

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12 July 2018

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IL-4 treatment can cure established gastrointestinal nematode infections in immunocompetent and immunodeficient mice.

12 July 2018

1 reference

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Infection with Nippostrongylus brasiliensis or injection of anti-IgD antibodies markedly enhances Fc-receptor-mediated interleukin 4 production by non-B, non-T cells

12 July 2018

1 reference

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Cross-linking Fc receptors stimulate splenic non-B, non-T cells to secrete interleukin 4 and other lymphokines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271435

Purified Fc epsilon R+ bone marrow and splenic non-B, non-T cells are highly enriched in the capacity to produce IL-4 in response to immobilized IgE, IgG2a, or ionomycin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271435

Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths.

12 July 2018

1 reference

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Basophils contribute to T(H)2-IgE responses in vivo via IL-4 production and presentation of peptide-MHC class II complexes to CD4+ T cells.

25 September 2018

1 reference

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Imaging of germinal center selection events during affinity maturation

25 September 2018

1 reference

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Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3271435

IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13.

25 September 2018

1 reference

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Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter

25 September 2018

1 reference

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MMCP-8, the first lineage-specific differentiation marker for mouse basophils. Elevated numbers of potent IL-4-producing and MMCP-8-positive cells in spleens of malaria-infected mice

25 September 2018

1 reference

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Cultured basophils but not cultured mast cells induce human IgE synthesis in B cells after immunologic stimulation

25 September 2018

1 reference

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Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

25 September 2018

1 reference

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Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells

15 November 2018

1 reference

12 December 2020

Expression profile of novel members of the rat mast cell protease (rMCP)-2 and (rMCP)-8 families, and functional analyses of mouse mast cell protease (mMCP)-8

1 reference

12 December 2020

Basophils enhance immunological memory responses

1 reference

12 December 2020

IL-3 promotes production of IL-4 by splenic non-B, non-T cells in response to Fc receptor cross-linkage

1 reference

12 December 2020

Basophils are essential initiators of a novel type of chronic allergic inflammation

1 reference

12 December 2020

Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites

1 reference

12 December 2020

Induction of Th2 type immunity in a mouse system reveals a novel immunoregulatory role of basophils

1 reference

12 December 2020

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30 July 2022

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30 July 2022