TRAIL and ceramide. (Q35756892)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110180%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

review article

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title

TRAIL and ceramide (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110180%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110180%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Yong J Lee

series ordinal

1

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27 December 2019

language of work or name

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1 January 2004

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110180%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

published in

Vitamins and Hormones

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110180%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

volume

67

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110180%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

page(s)

229-255

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Chromatin Neutral Sphingomyelinase and Its Role in Hepatic Regeneration

27 December 2019

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Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

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Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid

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Ceramide formation during heat shock: a potential mediator of alpha B-crystallin transcription

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Differential regulation of sphingomyelinase and ceramidase activities by growth factors and cytokines. Implications for cellular proliferation and differentiation

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Ceramide enables fas to cap and kill.

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Sphingosine 1-phosphate antagonizes apoptosis of human leukemia cells by inhibiting release of cytochrome c and Smac/DIABLO from mitochondria

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Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

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7 January 2021

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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7 January 2021

Retinoblastoma gene product as a downstream target for a ceramide-dependent pathway of growth arrest

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7 January 2021

p53-dependent ceramide response to genotoxic stress

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7 January 2021

Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family

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7 January 2021

The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

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7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

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7 January 2021

Reversible phosphorylation of Bcl2 following interleukin 3 or bryostatin 1 is mediated by direct interaction with protein phosphatase 2A

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7 January 2021

IAP family proteins--suppressors of apoptosis

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7 January 2021

Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors

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7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

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7 January 2021

Distribution of alkaline sphingomyelinase activity in human beings and animals. Tissue and species differences

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7 January 2021

Purification and characterization of a membrane-bound nonlysosomal ceramidase from rat brain

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7 January 2021

Molecular cloning and characterization of a human mitochondrial ceramidase

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7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

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7 January 2021

C16 ceramide accumulates following androgen ablation in LNCaP prostate cancer cells

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7 January 2021

Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

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7 January 2021

Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species

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7 January 2021

Magnesium-dependent sphingomyelinase

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7 January 2021

Apoptosis-induced by TRAIL AND TNF-alpha in human multiple myeloma cells is not blocked by BCL-2

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7 January 2021

Ceramide Induces CytochromecRelease from Isolated Mitochondria

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Stimulation of DNA synthesis by natural ceramide 1-phosphate

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Interaction of Ceramides, Sphingosine, and Sphingosine 1-Phosphate in Regulating DNA Synthesis and Phospholipase D Activity

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7 January 2021

CD95 Signaling via Ceramide-rich Membrane Rafts

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7 January 2021

Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL.

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7 January 2021

CD95(Fas/APO-1) signals ceramide generation independent of the effector stage of apoptosis

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7 January 2021

Ceramide profiling of complex lipid mixtures by electrospray ionization mass spectrometry

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7 January 2021

Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide

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7 January 2021

How TRAIL kills cancer cells, but not normal cells

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7 January 2021

Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis

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7 January 2021

Functions of ceramide in coordinating cellular responses to stress

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7 January 2021

Functions of sphingolipids and sphingolipid breakdown products in cellular regulation

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7 January 2021

Role of ceramide in stimulation of the transcription of cytosolic phospholipase A2 and cyclooxygenase 2.

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7 January 2021

Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells

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7 January 2021

Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

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7 January 2021

Role of glycogen synthase kinase-3beta in neuronal apoptosis induced by trophic withdrawal

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7 January 2021

Toso, a cell surface, specific regulator of Fas-induced apoptosis in T cells

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7 January 2021

Cloning and characterization of the mammalian brain-specific, Mg2+-dependent neutral sphingomyelinase

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7 January 2021

Acid sphingomyelinase deficient mice: a model of types A and B Niemann–Pick disease

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7 January 2021

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

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7 January 2021

Nitric oxide donors induce stress signaling via ceramide formation in rat renal mesangial cells

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7 January 2021

Activation of a nuclear sphingomyelinase in radiation-induced apoptosis

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7 January 2021

Role for ceramide in cell cycle arrest.

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Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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The lysosomal protease cathepsin D mediates apoptosis induced by oxidative stress.

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7 January 2021

Ceramide mediates tumor-induced dendritic cell apoptosis

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Type I interferons (IFNs) regulate tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) expression on human T cells: A novel mechanism for the antitumor effects of type I IFNs

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7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

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7 January 2021

Sphingomyelin and derivatives as cellular signals

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7 January 2021

The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling

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Interleukin-1 protects transformed keratinocytes from tumor necrosis factor-related apoptosis-inducing ligand- and CD95-induced apoptosis but not from ultraviolet radiation-induced apoptosis

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7 January 2021

FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

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7 January 2021

Ceramide induces interleukin 6 gene expression in human fibroblasts

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7 January 2021

The dimeric and catalytic subunit forms of protein phosphatase 2A from rat brain are stimulated by C2-ceramide

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7 January 2021

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

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7 January 2021

Sodium nitroprusside enhances TRAIL-induced apoptosis via a mitochondria-dependent pathway in human colorectal carcinoma CX-1 cells

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7 January 2021

Degradation of fluorescent and radiolabelled sphingomyelins in intact cells by a non-lysosomal pathway

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7 January 2021

Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death

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7 January 2021

Advances in the signal transduction of ceramide and related sphingolipids

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7 January 2021

Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-alpha-induced apoptosis

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Ceramide glycosylation potentiates cellular multidrug resistance

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7 January 2021

Cell autonomous apoptosis defects in acid sphingomyelinase knockout fibroblasts.

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7 January 2021

Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?

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7 January 2021

Differential effects of sphingomyelin hydrolysis and resynthesis on the activation of NF-kappa B in normal and SV40-transformed human fibroblasts

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7 January 2021

Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide

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7 January 2021

Human vascular endothelial cells are a rich and regulatable source of secretory sphingomyelinase. Implications for early atherogenesis and ceramide-mediated cell signaling

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7 January 2021

A novel receptor for Apo2L/TRAIL contains a truncated death domain

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7 January 2021

Signal transduction of stress via ceramide

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7 January 2021

Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta

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7 January 2021

Mitochondrial lipid alterations during Fas- and radiation-induced apoptosis

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7 January 2021

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

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7 January 2021

Quantitation of free sphingosine in liver by high-performance liquid chromatography

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7 January 2021

Purification, characterization, molecular cloning, and subcellular distribution of neutral ceramidase of rat kidney

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7 January 2021

Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway

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7 January 2021

Alkaline sphingomyelinases and ceramidases of the gastrointestinal tract

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7 January 2021

Identification of an alkaline sphingomyelinase activity in human bile

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7 January 2021

Purification and characterization of a novel ceramidase from Pseudomonas aeruginosa

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7 January 2021

Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease)

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7 January 2021

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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7 January 2021

The receptor for the cytotoxic ligand TRAIL

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7 January 2021

An Antagonist Decoy Receptor and a Death Domain-Containing Receptor for TRAIL

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7 January 2021

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

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7 January 2021

The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition

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7 January 2021

Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis

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7 January 2021

Serine palmitoyltransferase regulates de novo ceramide generation during etoposide-induced apoptosis

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7 January 2021

Ceramide in apoptosis: an overview and current perspectives

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7 January 2021

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

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7 January 2021

Sphingomyelin-derived lipids differentially regulate the extracellular signal-regulated kinase 2 (ERK-2) and c-Jun N-terminal kinase (JNK) signal cascades in airway smooth muscle

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7 January 2021

Ceramide mediates the apoptotic response of WEHI 231 cells to anti-immunoglobulin, corticosteroids and irradiation

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7 January 2021

The role of phosphoinositide 3-kinase lipid products in cell function

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7 January 2021

Cell cycle arrest induced by an inhibitor of glucosylceramide synthase. Correlation with cyclin-dependent kinases

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7 January 2021

Formation of free sphingosine and ceramide from exogenous ganglioside GM1 by cerebellar granule cells in culture.

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7 January 2021

Phosphatidylinositol 3' kinase: one of the effectors of Ras.

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7 January 2021

A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis

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7 January 2021

Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A

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Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.

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Modulation of Akt kinase activity by binding to Hsp90

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FAP-1: a protein tyrosine phosphatase that associates with Fas

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

The role of c-FLIP in modulation of CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Localization of neutral, magnesium-stimulated sphingomyelinase in plasma membrane of cultured neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Ceramide dissociates 3'-phosphoinositide production from pleckstrin homology domain translocation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Overexpression of acid ceramidase protects from tumor necrosis factor-induced cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

BAD Enables Ceramide to Signal Apoptosis via Ras and Raf-1

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Analysis of sphingomyelin, glucosylceramide, ceramide, sphingosine, and sphingosine 1-phosphate by tandem mass spectrometry.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Sequential operation of ceramide synthesis and ICE cascade in CPT-11-initiated apoptotic death signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Secretory sphingomyelinase

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Existence of Mg2+-dependent, neutral sphingomyelinase in nuclei of rat ascites hepatoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Molecular cloning of the full-length cDNA encoding mouse neutral ceramidase. A novel but highly conserved gene family of neutral/alkaline ceramidases

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Mass spectrometric identification of increased C16 ceramide levels during apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Apoptosis: Silencing the death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Enzymatic quantification of sphingosine in the picomole range in cultured cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

A neutral sphingomyelinase resides in sphingolipid-enriched microdomains and is inhibited by the caveolin-scaffolding domain: potential implications in tumour necrosis factor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Measles virus induces functional TRAIL production by human dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Fas-induced apoptosis of T cells occurs independently of ceramide generation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Ceramide activates the stress-activated protein kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Protein kinase CbetaII activation by 1-beta-D-arabinofuranosylcytosine is antagonistic to stimulation of apoptosis and Bcl-2alpha down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Induction of ceramide-mediated apoptosis by the anticancer phospholipid analog, hexadecylphosphocholine

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Potential role for cathepsin D in p53-dependent tumor suppression and chemosensitivity.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Kinase suppressor of Ras signals through Thr269 of c-Raf-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Natural killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cells

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Bcl-2 interrupts the ceramide-mediated pathway of cell death.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide

1 reference

https://api.crossref.org/works/10.1016%2FS0083-6729%2804%2967013-0

7 January 2021

10.1016/S0083-6729(04)67013-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15110180%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference