Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection (Q35750253)

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scientific article published on November 2001

Language	Label	Description	Also known as
English	Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection	scientific article published on November 2001

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Pivotal role of interleukin-12 and interferon-gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Trypanosoma cruzi

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author name string

V Michailowsky

1

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

N M Silva

2

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

C D Rocha

3

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

L Q Vieira

4

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

J Lannes-Vieira

5

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

R T Gazzinelli

6

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

language of work or name

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publication date

1 November 2001

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

The American Journal of Pathology

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Europe PubMed Central

PubMed publication ID

10 August 2017

159

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1723-1733

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Correlation between Trypanosoma cruzi parasitism and myocardial inflammatory infiltrate in human chronic chagasic myocarditis: Light microscopy and immunohistochemical findings

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

12 July 2018

Modulation of chagasic cardiomyopathy by interleukin-4: dissociation between inflammation and tissue parasitism

1 reference

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12 July 2018

Stage-dependent role of nitric oxide in control of Trypanosoma cruzi infection

1 reference

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12 July 2018

Tumor necrosis factor alpha-mediated toxic shock in Trypanosoma cruzi-infected interleukin 10-deficient mice

1 reference

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12 July 2018

Genetic characterization of Trypanosoma cruzi directly from tissues of patients with chronic Chagas disease: differential distribution of genetic types into diverse organs

1 reference

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12 July 2018

Effects of interleukin-4 deprivation and treatment on resistance to Trypanosoma cruzi

1 reference

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Trypanosoma cruzi meningoencephalitis in HIV-infected patients

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Influence of acute-phase parasite load on pathology, parasitism, and activation of the immune system at the late chronic phase of Chagas' disease

1 reference

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12 July 2018

Interleukin-12 enhances in vivo parasiticidal effect of benznidazole during acute experimental infection with a naturally drug-resistant strain of Trypanosoma cruzi

1 reference

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Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans

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Defective nitric oxide effector functions lead to extreme susceptibility of Trypanosoma cruzi-infected mice deficient in gamma interferon receptor or inducible nitric oxide synthase

1 reference

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12 July 2018

Trypanosoma cruzi induces strong IL-12 and IL-18 gene expression in vivo: correlation with interferon-gamma (IFN-gamma) production

1 reference

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12 July 2018

Immunological control of Trypanosoma cruzi infection and pathogenesis of Chagas' disease.

1 reference

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12 July 2018

Cardiac involvement is a constant finding in acute Chagas' disease: a clinical, parasitological and histopathological study

1 reference

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12 July 2018

Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

12 July 2018

Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells

1 reference

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12 July 2018

Depletion of T-cell subpopulations results in exacerbation of myocarditis and parasitism in experimental Chagas' disease

1 reference

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12 July 2018

Pathology of patients with Chagas' disease and acquired immunodeficiency syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

12 July 2018

Impaired interleukin 12 production in human immunodeficiency virus-infected patients

1 reference

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12 July 2018

T cell genetic background determines default T helper phenotype development in vitro

1 reference

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12 July 2018

Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

12 July 2018

Nitric oxide is involved in control of Trypanosoma cruzi-induced parasitemia and directly kills the parasite in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

12 July 2018

Genetic control of responses to Trypanosoma cruzi in mice: multiple genes influencing parasitemia and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

12 July 2018

Genetics of murine resistance to Trypanosoma cruzi.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

12 July 2018

Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

12 July 2018

The indeterminate form of human chronic Chagas' disease A clinical epidemiological review

1 reference

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12 July 2018

Influence of Trypanosoma cruzi strain on the pathogenesis of chronic myocardiopathy in mice

1 reference

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12 July 2018

Endogenous IFN-gamma is required for resistance to acute Trypanosoma cruzi infection in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

12 July 2018

Anti-CD4 abrogates rejection and reestablishes long-term tolerance to syngeneic newborn hearts grafted in mice chronically infected with Trypanosoma cruzi

1 reference

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12 July 2018

The microbicidal activity of interferon-gamma-treated macrophages against Trypanosoma cruzi involves an L-arginine-dependent, nitrogen oxide-mediated mechanism inhibitable by interleukin-10 and transforming growth factor-beta

1 reference

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12 July 2018

CHRONIC AND PROGRESSIVE MYOCARDITIS AND MYOSITIS IN C3H MICE INFECTED WITH TRYPANOSOMA CRUZI.

1 reference

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25 September 2018

Increased susceptibility of Stat4-deficient and enhanced resistance in Stat6-deficient mice to infection with Trypanosoma cruzi

1 reference

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25 September 2018

Reactivation of Chagas' disease in a human immunodeficiency virus-infected patient leading to severe heart disease with a late positive direct microscopic examination of the blood.

1 reference

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25 September 2018

Trypanosoma cruzi: IL-10, TNF, IFN-gamma, and IL-12 regulate innate and acquired immunity to infection.

1 reference

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25 September 2018

Kinetics of cytokine gene expression in experimental chagasic cardiomyopathy: tissue parasitism and endogenous IFN-gamma as important determinants of chemokine mRNA expression during infection with Trypanosoma cruzi

2 references

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Chagas' disease encephalitis: intense CD8+ lymphocytic infiltrate is restricted to the acute phase, but is not related to the presence of Trypanosoma cruzi antigens

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15 November 2018

Differential tissue distribution of diverse clones of Trypanosoma cruzi in infected mice

1 reference

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Myocardial parasite persistence in chronic chagasic patients

1 reference

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An in situ quantitative immunohistochemical study of cytokines and IL-2R+ in chronic human chagasic myocarditis: correlation with the presence of myocardial Trypanosoma cruzi antigens

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15 November 2018

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IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi

1 reference

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Amplification of a Trypanosoma cruzi DNA sequence from inflammatory lesions in human chagasic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277321

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Chagasic meningoencephalitis with detection of Trypanosoma cruzi in the cerebrospinal fluid of an immunodepressed patient

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Chagas' disease: Trypanosoma cruzi vs. the host immune system

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15 November 2018

https://pubmed.ncbi.nlm.nih.gov/11696433

12 December 2020

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The mechanisms of Trypanosoma cruzi invasion of mammalian cells

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Interleukin-4 and interferon-gamma: the quintessence of a mutual antagonistic relationship

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Cutting edge: IL-12 is required for the maintenance of IFN-gamma production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)63019-2

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

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