ECSASB2 mediates MLL degradation during hematopoietic differentiation (Q35750333)

10 August 2017

title

ECSASB2 mediates MLL degradation during hematopoietic differentiation (English)

1 reference

10 August 2017

Jingya Wang

1

1 reference

10 August 2017

Andrew G Muntean

series ordinal

2

1 reference

10 August 2017

Jay L Hess

series ordinal

3

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10 August 2017

language of work or name

English

0 references

publication date

15 December 2011

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10 August 2017

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10 August 2017

volume

119

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10 August 2017

issue

5

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10 August 2017

page(s)

1151-1161

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A mechanism underlying NOTCH-induced and ubiquitin-mediated JAK3 degradation

10 August 2017

cites work

1 reference

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12 July 2018

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Regulation of the histone H4 monomethylase PR-Set7 by CRL4(Cdt2)-mediated PCNA-dependent degradation during DNA damage

12 July 2018

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The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells.

12 July 2018

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CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase

12 July 2018

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CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation

12 July 2018

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Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint

12 July 2018

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The PHD3 Domain of MLL Acts as a CYP33-Regulated Switch between MLL-Mediated Activation and Repression,

12 July 2018

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The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis

12 July 2018

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Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression

12 July 2018

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Molecular Mechanism of MLL PHD3 and RNA Recognition by the Cyp33 RRM Domain

12 July 2018

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Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription

12 July 2018

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MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.

12 July 2018

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12 July 2018

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Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.

12 July 2018

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The E3 ubiquitin ligase specificity subunit ASB2beta is a novel regulator of muscle differentiation that targets filamin B to proteasomal degradation

12 July 2018

1 reference

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ASB2 targets filamins A and B to proteasomal degradation

12 July 2018

1 reference

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The PHD fingers of MLL block MLL fusion protein-mediated transformation

12 July 2018

1 reference

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C/EBPalpha and C/EBPvarepsilon induce the monocytic differentiation of myelomonocytic cells with the MLL-chimeric fusion gene

12 July 2018

1 reference

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Loss of MLL PHD finger 3 is necessary for MLL-ENL-induced hematopoietic stem cell immortalization

12 July 2018

1 reference

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Ankyrin repeat and suppressor of cytokine signaling (SOCS) box-containing protein (ASB) 15 alters differentiation of mouse C2C12 myoblasts and phosphorylation of mitogen-activated protein kinase and Akt.

12 July 2018

1 reference

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Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors

12 July 2018

1 reference

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Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.

12 July 2018

1 reference

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Hox genes in hematopoiesis and leukemogenesis.

12 July 2018

1 reference

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Bimodal degradation of MLL by SCFSkp2 and APCCdc20 assures cell cycle execution: a critical regulatory circuit lost in leukemogenic MLL fusions

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Ankyrin repeat and SOCS box containing protein 4 (Asb-4) interacts with GPS1 (CSN1) and inhibits c-Jun NH2-terminal kinase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

12 July 2018

1 reference

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Chromatin structural elements and chromosomal translocations in leukemia

12 July 2018

1 reference

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Chromosomal translocations involving the MLL gene: molecular mechanisms

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

MLL associates specifically with a subset of transcriptionally active target genes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor II

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Mechanisms of transformation by MLL.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

An Mll-dependent Hox program drives hematopoietic progenitor expansion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

A statistical model for identifying proteins by tandem mass spectrometry

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

MLL targets SET domain methyltransferase activity to Hox gene promoters

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

ASB-2 inhibits growth and promotes commitment in myeloid leukemia cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

ATRA-regulated Asb-2 gene induced in differentiation of HL-60 leukemia cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Functional analysis of Asb-1 using genetic modification in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Protein structure modeling for structural genomics.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Altered Hox expression and segmental identity in Mll-mutant mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

NUP98-MLL fusion in human acute myeloblastic leukemia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277351

10.1182/BLOOD-2011-06-362079

25 September 2018

Identifiers

DOI

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10 August 2017

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10 August 2017

1 reference