Self-reactive human CD4 T cell clones form unusual immunological synapses (Q35760826)

10 August 2017

title

Self-reactive human CD4 T cell clones form unusual immunological synapses (English)

1 reference

10 August 2017

1 reference

Santosh Vardhana

4

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Kaushik Choudhuri

Kaushik Choudhuri

8

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Brian D Evavold

Brian D Evavold

11

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Gerald T Nepom

Gerald T Nepom

10

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Michael L Dustin

Michael L Dustin

12

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author name string

David A Schubert

1

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10 August 2017

Susana Gordo

2

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10 August 2017

Joseph J Sabatino

3

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10 August 2017

Etienne Gagnon

5

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10 August 2017

Dhruv K Sethi

6

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10 August 2017

Nilufer P Seth

7

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10 August 2017

Helena Reijonen

9

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10 August 2017

Kai W Wucherpfennig

13

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10 August 2017

language of work or name

English

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publication date

6 February 2012

1 reference

Journal of Experimental Medicine

10 August 2017

published in

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10 August 2017

volume

209

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10 August 2017

issue

2

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10 August 2017

page(s)

335-352

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New insights into the T cell synapse from single molecule techniques

10 August 2017

cites work

1 reference

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Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection

2 October 2017

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HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide

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T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta

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2 October 2017

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2 October 2017

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2 October 2017

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Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'

2 October 2017

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Risk alleles for multiple sclerosis identified by a genomewide study

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T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule

2 October 2017

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2 October 2017

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Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity

2 October 2017

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T cell receptor antagonism interferes with MHC clustering and integrin patterning during immunological synapse formation

2 October 2017

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A single class II myosin modulates T cell motility and stopping, but not synapse formation

2 October 2017

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T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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T cell receptor signaling precedes immunological synapse formation

2 October 2017

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Identification and modulation of a naturally processed T cell epitope from the diabetes-associated autoantigen human glutamic acid decarboxylase 65 (hGAD65).

2 October 2017

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2 October 2017

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High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire

2 October 2017

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The immunological synapse: a molecular machine controlling T cell activation

2 October 2017

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Three-dimensional segregation of supramolecular activation clusters in T cells

2 October 2017

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Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation

2 October 2017

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2 October 2017

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Conformation of human leukocyte antigen class II molecules. Evidence for superdimers and empty molecules on human antigen presenting cells

2 October 2017

1 reference

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Serial triggering of many T-cell receptors by a few peptide-MHC complexes

2 October 2017

1 reference

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Chinese hamster ovary cell mutants with multiple glycosylation defects for production of glycoproteins with minimal carbohydrate heterogeneity

2 October 2017

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The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice

2 October 2017

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The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse

2 October 2017

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Induction of rapid T cell activation and tolerance by systemic presentation of an orally administered antigen.

12 July 2018

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The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

12 July 2018

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The major myelin protein genes are expressed in the human thymus

12 July 2018

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Structural requirements for binding of an immunodominant myelin basic protein peptide to DR2 isotypes and for its recognition by human T cell clones

12 July 2018

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HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

12 July 2018

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Kinetics of MHC-CD8 interaction at the T cell membrane.

12 July 2018

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Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

25 September 2018

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GAD65-specific CD4+ T-cells with high antigen avidity are prevalent in peripheral blood of patients with type 1 diabetes

25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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Crossref

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Supported Planar Bilayers for Study of the Immunological Synapse

21 January 2018

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Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

21 January 2018

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PubMed

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Identifiers

DOI

10.1084/JEM.20111485

1 reference

release_psykcoxl5vf3lgc6k5hsg5wusa

10 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/psykcoxl5vf3lgc6k5hsg5wusa

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3280872

1 reference

10 August 2017

1 reference