Mesenchymal stem cell therapy for doxorubicin cardiomyopathy: hopes and fears (Q35774310)

10 August 2017

3 references

22 March 2019

17 June 2019

25 June 2019

Mesenchymal stem cell therapy for doxorubicin cardiomyopathy: hopes and fears (English)

1 reference

10 August 2017

3 references

22 March 2019

17 June 2019

25 June 2019

mesenchymal stem cell

1 reference

1 reference

Fernando Ezquer

1

1 reference

10 August 2017

Jaime Gutiérrez

2

1 reference

10 August 2017

Marcelo Ezquer

3

1 reference

10 August 2017

Christian Caglevic

4

1 reference

10 August 2017

Helio C Salgado

5

1 reference

10 August 2017

Sebastián D Calligaris

6

1 reference

10 August 2017

language of work or name

1 reference

24 June 2015

4 references

Stem Cell Research & Therapy

10 August 2017

22 March 2019

17 June 2019

25 June 2019

4 references

10 August 2017

22 March 2019

17 June 2019

25 June 2019

6

1 reference

10 August 2017

page(s)

116

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Creative Commons Attribution

10 August 2017

copyright license

3 references

22 March 2019

17 June 2019

25 June 2019

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on focus list of Wikimedia project

ScienceSource

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cites work

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Early increases in multiple biomarkers predict subsequent cardiotoxicity in patients with breast cancer treated with doxorubicin, taxanes, and trastuzumab

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Altered features and increased chemosensitivity of human breast cancer cells mediated by adipose tissue-derived mesenchymal stromal cells

12 July 2018

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Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions

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Mesenchymal stem cells for anti-cancer drug delivery

12 July 2018

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Distribution of the anticancer drugs doxorubicin, mitoxantrone and topotecan in tumors and normal tissues.

12 July 2018

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Cardiotoxicity associated with cancer therapy: pathophysiology and prevention strategies

12 July 2018

1 reference

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Effect of mesenchymal stem cells on Doxorubicin-induced fibrosis

12 July 2018

1 reference

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Doxorubicin Cardiotoxicity and Cardiac Function Improvement After Stem Cell Therapy Diagnosed by Strain Echocardiography

12 July 2018

1 reference

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Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems.

12 July 2018

1 reference

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Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials

12 July 2018

1 reference

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Induced pluripotency and oncogenic transformation are related processes

12 July 2018

1 reference

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Toll-like receptor (TLR) 2 and TLR4 differentially regulate doxorubicin induced cardiomyopathy in mice.

12 July 2018

1 reference

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Noninvasive diagnosis of chemotherapy related cardiotoxicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Anthracycline cardiotoxicity: prevalence, pathogenesis and treatment

12 July 2018

1 reference

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Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy

12 July 2018

1 reference

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Global cancer transitions according to the Human Development Index (2008-2030): a population-based study.

12 July 2018

1 reference

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Chemotherapy induced cardiomyopathy: pathogenesis, monitoring and management

12 July 2018

1 reference

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Cardiac cell therapy: boosting mesenchymal stem cells effects

12 July 2018

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Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial

12 July 2018

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Inflammation in myocardial diseases

12 July 2018

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RETRACTED: Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial

12 July 2018

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Original article anti-oxidant pathways are stimulated by mesenchymal stromal cells in renal repair after ischemic injury

12 July 2018

1 reference

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Medical interventions for treating anthracycline-induced symptomatic and asymptomatic cardiotoxicity during and after treatment for childhood cancer

12 July 2018

1 reference

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Bone marrow-derived cell therapy stimulates endogenous cardiomyocyte progenitors and promotes cardiac repair

12 July 2018

1 reference

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Cardiovascular effects in childhood cancer survivors treated with anthracyclines

12 July 2018

1 reference

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Concise review: Dissecting a discrepancy in the literature: do mesenchymal stem cells support or suppress tumor growth?

12 July 2018

1 reference

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Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiation

12 July 2018

1 reference

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Anticancer therapy induced cardiotoxicity: review of the literature

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Mesenchymal stem cell therapy: Two steps forward, one step back

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Juvenile exposure to anthracyclines impairs cardiac progenitor cell function and vascularization resulting in greater susceptibility to stress-induced myocardial injury in adult mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Anthracycline cardiomyopathy is mediated by depletion of the cardiac stem cell pool and is rescued by restoration of progenitor cell function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: retrospective analysis of the Childhood Cancer Survivor Study cohort

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Bone marrow-derived stem cells attenuate impaired contractility and enhance capillary density in a rabbit model of Doxorubicin-induced failing hearts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Cause-specific late mortality among 5-year survivors of childhood cancer: the Childhood Cancer Survivor Study

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Metastatic breast cancer: the role of pegylated liposomal doxorubicin after conventional anthracyclines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Mesenchymal stem cells avoid allogeneic rejection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Adult cardiac stem cells are multipotent and support myocardial regeneration

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Differential effects of chemotherapeutic agents on the Bcl-2/Bax apoptosis pathway in human breast cancer cell line MCF-7.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Bcl-2 and the regulation of programmed cell death

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Interference by doxorubicin with DNA unwinding in MCF-7 breast tumor cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Redox cycling of anthracyclines by cardiac mitochondria. II. Formation of superoxide anion, hydrogen peroxide, and hydroxyl radical.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Toxicity profile of dexrazoxane (zinecardR, icrf-187, adr-529, nsc-169780), a modulator of doxorubicin cardiotoxicity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Early biomarkers of doxorubicin-induced heart injury in a mouse model.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Adipose tissue-derived mesenchymal stem cells cultured at high density express IFN-β and suppress the growth of MCF-7 human breast cancer cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Impact of repeated intravenous bone marrow mesenchymal stem cells infusion on myocardial collagen network remodeling in a rat model of doxorubicin-induced dilated cardiomyopathy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Doxorubicin caused apoptosis of mesenchymal stem cells via p38, JNK and p53 pathway.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Activation of the p38 MAPK/NF-κB pathway contributes to doxorubicin-induced inflammation and cytotoxicity in H9c2 cardiac cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

The protective effects of ω-3 fatty acids on doxorubicin-induced hepatotoxicity and nephrotoxicity in rats

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Doxorubicin induces senescence and impairs function of human cardiac progenitor cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Mesenchymal stem cell therapy promotes renal repair by limiting glomerular podocyte and progenitor cell dysfunction in adriamycin-induced nephropathy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Induced pluripotent stem cell (iPSC)-derived Flk-1 progenitor cells engraft, differentiate, and improve heart function in a mouse model of acute myocardial infarction

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Human umbilical cord blood derived stem cells repair doxorubicin-induced pathological cardiac hypertrophy in mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Preliminary results of a longitudinal study of changes in cognitive function in breast cancer patients undergoing chemotherapy with doxorubicin and cyclophosphamide

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Cyclooxygenase-2 inhibitor treatment improves left ventricular function and mortality in a murine model of doxorubicin-induced heart failure

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Cardiac cell toxicity induced by 4-hydroperoxycyclophosphamide is modulated by glutathione.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478637

Clinical and morphologic cardiac findings after anthracycline chemotherapy. Analysis of 64 patients studied at necropsy

25 September 2018

1 reference

12 December 2020

Anthracycline-induced suppression of GATA-4 transcription factor: implication in the regulation of cardiac myocyte apoptosis

1 reference

12 December 2020

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

1 reference

12 December 2020

Effects of autologous stem cell transplantation on ventricular electrophysiology in doxorubicin-induced heart failure

1 reference

12 December 2020

Isolation and expansion of adult cardiac stem cells from human and murine heart

1 reference

12 December 2020

Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species

1 reference

12 December 2020

Cardiac stem cells: isolation, expansion and experimental use for myocardial regeneration

1 reference

12 December 2020

Human umbilical cord mesenchymal stromal cells mitigate chemotherapy-associated tissue injury in a pre-clinical mouse model

1 reference

12 December 2020

10.1186/S13287-015-0109-Y

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10 August 2017

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10 August 2017

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