Understanding the failure of CD8+ T-cell vaccination against simian/human immunodeficiency virus (Q35784787)

10 August 2017

title

Understanding the failure of CD8+ T-cell vaccination against simian/human immunodeficiency virus (English)

1 reference

10 August 2017

Rob J De Boer

1

1 reference

10 August 2017

language of work or name

English

0 references

publication date

3 January 2007

1 reference

10 August 2017

1 reference

10 August 2017

volume

81

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10 August 2017

issue

6

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10 August 2017

page(s)

2838-2848

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Long-lasting decrease in viremia in macaques chronically infected with simian immunodeficiency virus SIVmac251 after therapeutic DNA immunization

10 August 2017

cites work

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Cytotoxic T-lymphocyte escape does not always explain the transient control of simian immunodeficiency virus SIVmac239 viremia in adenovirus-boosted and DNA-primed Mamu-A*01-positive rhesus macaques

27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

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High-potency human immunodeficiency virus vaccination leads to delayed and reduced CD8+ T-cell expansion but improved virus control

27 July 2018

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CD8+ T-lymphocyte response to major immunodominant epitopes after vaginal exposure to simian immunodeficiency virus: too late and too little

27 July 2018

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Immunization of macaques with single-cycle simian immunodeficiency virus (SIV) stimulates diverse virus-specific immune responses and reduces viral loads after challenge with SIVmac239

27 July 2018

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Rapid viral escape at an immunodominant simian-human immunodeficiency virus cytotoxic T-lymphocyte epitope exacts a dramatic fitness cost

27 July 2018

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27 July 2018

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Contrasting B cell- and T cell-based protective vaccines.

27 July 2018

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Predicting the impact of a nonsterilizing vaccine against human immunodeficiency virus

27 July 2018

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Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein

27 July 2018

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Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

27 July 2018

1 reference

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Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys

27 July 2018

1 reference

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Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation

27 July 2018

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Epitope dominance, competition and T cell affinity maturation

27 July 2018

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Antiviral memory T-cell responses in the lung

27 July 2018

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Immunity, immunopathology and vaccines against HIV?

27 July 2018

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Estimating the precursor frequency of naive antigen-specific CD8 T cells

27 July 2018

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ALVAC-SIV-gag-pol-env-based vaccination and macaque major histocompatibility complex class I (A*01) delay simian immunodeficiency virus SIVmac-induced immunodeficiency

27 July 2018

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Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection

27 July 2018

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Role of CD8(+) lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment

27 July 2018

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Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses

27 July 2018

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Modeling immune responses with handling time.

27 July 2018

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Effects of in vivo CD8(+) T cell depletion on virus replication in rhesus macaques immunized with a live, attenuated simian immunodeficiency virus vaccine.

27 July 2018

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HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi.

27 July 2018

1 reference

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Specific therapy regimes could lead to long-term immunological control of HIV.

27 July 2018

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Rapid production and clearance of HIV-1 and hepatitis C virus assessed by large volume plasma apheresis

27 July 2018

1 reference

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Viral dynamics of acute HIV-1 infection

27 July 2018

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Protection by live, attenuated simian immunodeficiency virus against heterologous challenge.

27 July 2018

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T cell dynamics in HIV-1 infection.

27 July 2018

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Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage

27 July 2018

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Virus-specific CD8+ T cells in primary and secondary influenza pneumonia

27 July 2018

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Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques

27 July 2018

1 reference

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Viral dynamics of primary viremia and antiretroviral therapy in simian immunodeficiency virus infection

27 July 2018

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Protection against immunopathological consequences of a viral infection by activated but not resting cytotoxic T cells: T cell memory without "memory T cells"?

27 July 2018

1 reference

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Quantitative image analysis of HIV-1 infection in lymphoid tissue

27 July 2018

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HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

27 July 2018

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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

27 July 2018

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27 July 2018

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HIV replication elicits little cytopathic effects in vivo: analysis of surrogate markers for virus production, cytotoxic T cell response and infected cell death

27 July 2018

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25 September 2018

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25 September 2018

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A functional CD8+ cell assay reveals individual variation in CD8+ cell antiviral efficacy and explains differences in human T-lymphotropic virus type 1 proviral load

25 September 2018

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Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

25 September 2018

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Kinetics of expansion of SIV Gag-specific CD8+ T lymphocytes following challenge of vaccinated macaques

25 September 2018

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Dynamic immune responses maintain cytotoxic T lymphocyte epitope mutations in transmitted simian immunodeficiency virus variants

25 September 2018

1 reference

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On the validity of the quasi-steady state approximation of bimolecular reactions in solution.

25 September 2018

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Therapeutic dendritic-cell vaccine for chronic HIV-1 infection

25 September 2018

1 reference

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HIV and SIV CTL escape: implications for vaccine design

25 September 2018

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Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial

25 September 2018

1 reference

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Estimates of intracellular delay and average drug efficacy from viral load data of HIV-infected individuals under antiretroviral therapy.

25 September 2018

1 reference

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Roles of target cells and virus-specific cellular immunity in primary simian immunodeficiency virus infection

25 September 2018

1 reference

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HIV vaccine design and the neutralizing antibody problem

25 September 2018

1 reference

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The collagen binding alpha1beta1 integrin VLA-1 regulates CD8 T cell-mediated immune protection against heterologous influenza infection.

25 September 2018

1 reference

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Glancing behind virus load variation in HIV-1 infection

25 September 2018

1 reference

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The race between initial T-helper expansion and virus growth upon HIV infection influences polyclonality of the response and viral set-point.

25 September 2018

1 reference

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Cutting edge: rapid in vivo killing by memory CD8 T cells

25 September 2018

1 reference

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Tat-vaccinated macaques do not control simian immunodeficiency virus SIVmac239 replication

25 September 2018

1 reference

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Resource competition determines selection of B cell repertoires.

25 September 2018

1 reference

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Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity

25 September 2018

1 reference

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T cells down-modulate peptide-MHC complexes on APCs in vivo.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

The immunological synapse of CTL contains a secretory domain and membrane bridges.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Effect of drug efficacy and the eclipse phase of the viral life cycle on estimates of HIV viral dynamic parameters

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Small variations in multiple parameters account for wide variations in HIV-1 set-points: a novel modelling approach.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

T cells compete for access to antigen-bearing antigen-presenting cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

What is missing in immunology to understand immunity?

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Accessing complexity: the dynamics of virus-specific T cell responses.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Protective immunity induced by live attenuated simian immunodeficiency virus

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Target cell limited and immune control models of HIV infection: a comparison

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Extending the quasi-steady state approximation by changing variables.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Anti-CD4 therapy for AIDS suggested by mathematical models.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Population dynamics of immune responses to persistent viruses.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Reduction of HIV concentration during acute infection: independence from a specific immune response.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

T cell repertoires and competitive exclusion.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Viral dynamics in human immunodeficiency virus type 1 infection

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Towards a general function describing T cell proliferation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression f

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

Immune control of HIV-1 after early treatment of acute infection

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1865966

The total quasi-steady-state approximation is valid for reversible enzyme kinetics

15 November 2018

1 reference

12 December 2020

Quantitative intracellular kinetics of HIV type 1

1 reference

12 December 2020

HIV swiftly guts the immune system

1 reference

12 December 2020

1 reference

12 December 2020

HIV-1 DNA/MVA vaccination reduces the per exposure probability of infection during repeated mucosal SHIV challenges

1 reference

12 December 2020

A single vaccination with attenuated SIVmac 239 via the tonsillar route confers partial protection against challenge with SIVmac 251 at a distant mucosal site, the rectum

1 reference

12 December 2020

Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.01914-06

1 reference

10 August 2017

1 reference

10 August 2017

1 reference