Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation (Q35788039)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10595918%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

title

Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation (English)

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2 November 2019

4

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2 November 2019

author name string

G P Nielsen

1

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2 November 2019

A O Stemmer-Rachamimov

2

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2 November 2019

Y Ino

3

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2 November 2019

A E Rosenberg

5

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2 November 2019

D N Louis

6

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2 November 2019

language of work or name

English

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publication date

1 December 1999

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The American Journal of Pathology

2 November 2019

published in

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2 November 2019

volume

155

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2 November 2019

issue

6

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2 November 2019

page(s)

1879-1884

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Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas

2 November 2019

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CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations

12 July 2018

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Loss of heterozygosity on chromosome 9q21 (p16 gene) uncommon in soft-tissue sarcomas

12 July 2018

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

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12 July 2018

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12 July 2018

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Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb.

12 July 2018

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12 July 2018

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Cytogenetics of tumors of soft tissue and bone. Implication for pathology

12 July 2018

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Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

12 July 2018

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Mutations of cell cycle regulators. Biological and clinical implications for human neoplasia

12 July 2018

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Neurofibromatosis type 1: pathology, clinical features and molecular genetics.

12 July 2018

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Growth suppression by p16ink4 requires functional retinoblastoma protein

12 July 2018

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Immunohistochemical and molecular analysis of p53, MDM2, proliferating cell nuclear antigen and Ki67 in benign and malignant peripheral nerve sheath tumours.

12 July 2018

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Benign neurofibromas in type 1 neurofibromatosis (NF1) show somatic deletions of the NF1 gene

12 July 2018

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A novel p16INK4A transcript

12 July 2018

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Malignant peripheral nerve sheath tumors. A clinicopathologic study of 120 cases

12 July 2018

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Molecular genetic analysis of tumors in von Recklinghausen neurofibromatosis: loss of heterozygosity for chromosome 17.

12 July 2018

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Chromosome 17p deletions and p53 gene mutations associated with the formation of malignant neurofibrosarcomas in von Recklinghausen neurofibromatosis

12 July 2018

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A (CA)n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens.

12 July 2018

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Plexiform neurofibroma with and without associated malignant peripheral nerve sheath tumor: a clinicopathologic and immunohistochemical analysis of 54 cases.

12 July 2018

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Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas

25 September 2018

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25 September 2018

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Malignant astrocytomas with homozygous CDKN2/p16 gene deletions have higher Ki-67 proliferation indices

25 September 2018

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25 September 2018

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25 September 2018

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15 November 2018

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p

7 January 2021

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Oncogenic aberrations of p16INK4/CDKN2 and cyclin D1 cooperate to deregulate G1 control

7 January 2021

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12 December 2020

Gain of 17q24-qter detected by comparative genomic hybridization in malignant tumors from patients with von Recklinghausen's neurofibromatosis

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12 December 2020

Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas

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12 December 2020

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12 December 2020

Candidate tumor-suppressor genes MTS1 (p16INK4A) and MTS2 (p15INK4B) display frequent homozygous deletions in primary cells from T- but not from B-cell lineage acute lymphoblastic leukemias

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12 December 2020

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10595918%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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2 November 2019

PubMed publication ID

10595918

1 reference