Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer (Q35809752)

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scientific article published on March 2000

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English	Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer	scientific article published on March 2000

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Amplification and deletion of topoisomerase IIalpha associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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author name string

T A Järvinen

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

M Tanner

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

V Rantanen

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

M Bärlund

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

A Borg

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

S Grénman

6

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Europe PubMed Central

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10 August 2017

J Isola

7

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Europe PubMed Central

PMC publication ID

10 August 2017

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publication date

1 March 2000

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Europe PubMed Central

PMC publication ID

10 August 2017

The American Journal of Pathology

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Europe PubMed Central

PMC publication ID

10 August 2017

156

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Europe PubMed Central

PMC publication ID

10 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

839-847

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Characterization of topoisomerase II alpha gene amplification and deletion in breast cancer

1 reference

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Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers

1 reference

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Apoptosis, p53, and tumor cell sensitivity to anticancer agents

1 reference

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MDR1 gene expression in primary and advanced breast cancer.

1 reference

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HER-2/neu as a predictive marker of response to breast cancer therapy

1 reference

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A multivariate analysis of tumour biological factors predicting response to cytotoxic treatment in advanced breast cancer

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Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

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Genetic aberrations in hypodiploid breast cancer: frequent loss of chromosome 4 and amplification of cyclin D1 oncogene

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Predictive value of topoisomerase IIalpha and other prognostic factors for epirubicin chemotherapy in advanced breast cancer

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Interstitial deletions and intrachromosomal amplification initiated from a double-strand break targeted to a mammalian chromosome

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HER-2/neu gene amplification characterized by fluorescence in situ hybridization: poor prognosis in node-negative breast carcinomas

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Cell cycle-coupled relocation of types I and II topoisomerases and modulation of catalytic enzyme activities

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Differential expression of DNA topoisomerase II alpha and -beta in P-gp and MRP-negative VM26, mAMSA and mitoxantrone-resistant sublines of the human SCLC cell line GLC4.

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Primary chemotherapy in breast invasive carcinoma: predictive value of the immunohistochemical detection of hormonal receptors, p53, c-erbB-2, MiB1, pS2 and GST pi.

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Transfection of human topoisomerase II alpha into etoposide-resistant cells: transient increase in sensitivity followed by down-regulation of the endogenous gene

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DNA topoisomerases

1 reference

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Selection of a subpopulation with fewer DNA topoisomerase II alpha gene copies in a doxorubicin-resistant cell line panel

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10.1016/S0002-9440(10)64952-8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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