Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo (Q35803282)

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scientific article published on September 2003

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English	Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo	scientific article published on September 2003

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Herpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1 reference

based on heuristic

inferred from title

author name string

Jenny A Murphy

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Rebecca J Duerst

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Tracy J Smith

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Lynda A Morrison

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 September 2003

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Europe PubMed Central

PMC publication ID

10 August 2017

Journal of Virology

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Europe PubMed Central

PMC publication ID

10 August 2017

77

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

17

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

9337-9345

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Cell surface major histocompatibility complex class II proteins are regulated by the products of the gamma(1)34.5 and U(L)41 genes of herpes simplex virus 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Interferon-producing cells: on the front line in immune responses against pathogens

1 reference

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11 July 2018

The immediate-early protein, ICP0, is essential for the resistance of herpes simplex virus to interferon-alpha/beta

1 reference

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Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation

1 reference

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11 July 2018

Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Herpes simplex virus ICP0 and ICP34.5 counteract distinct interferon-induced barriers to virus replication

1 reference

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11 July 2018

The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors

1 reference

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Activation of interferon response factor-3 in human cells infected with herpes simplex virus type 1 or human cytomegalovirus

1 reference

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11 July 2018

Participation of type I interferon in the decreased virulence of the UL13 gene-deleted mutant of herpes simplex virus type 1.

1 reference

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11 July 2018

Activation of cellular interferon-responsive genes after infection of human cells with herpes simplex virus type 1.

1 reference

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Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene

1 reference

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11 July 2018

Herpes simplex virus virion host shutoff (vhs) activity alters periocular disease in mice

1 reference

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11 July 2018

Herpes simplex virus ICP0 mutants are hypersensitive to interferon

1 reference

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Picornavirus internal ribosome entry site elements target RNA cleavage events induced by the herpes simplex virus virion host shutoff protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

The herpes simplex virus vhs protein induces endoribonucleolytic cleavage of target RNAs in cell extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Interferons regulate the phenotype of wild-type and mutant herpes simplex viruses in vivo

1 reference

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11 July 2018

The herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Reovirus induction of and sensitivity to beta interferon in cardiac myocyte cultures correlate with induction of myocarditis and are determined by viral core proteins.

1 reference

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11 July 2018

Mutational analysis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): characterization of HSV type 1 (HSV-1)/HSV-2 chimeras

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

The virion host shutoff function of herpes simplex virus type 1 plays a role in corneal invasion and functions independently of the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

A herpesvirus genetic element which affects translation in the absence of the viral GADD34 function

1 reference

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11 July 2018

The virion host shutoff protein of herpes simplex virus type 1: messenger ribonucleolytic activity in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Human herpes simplex virus (HSV)-specific CD8+ CTL clones recognize HSV-2-infected fibroblasts after treatment with IFN-gamma or when virion host shutoff functions are disabled

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase

1 reference

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11 July 2018

ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency.

1 reference

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11 July 2018

HLA class I molecules are not transported to the cell surface in cells infected with herpes simplex virus types 1 and 2.

1 reference

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Production of host shutoff-defective mutants of herpes simplex virus type 1 by inactivation of the UL13 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Functional role of type I and type II interferons in antiviral defense

1 reference

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11 July 2018

Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5- mutants of her

1 reference

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11 July 2018

Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides

1 reference

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11 July 2018

Herpes simplex virus types 1 and 2 induce shutoff of host protein synthesis by different mechanisms in Friend erythroleukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Induction of both thymidine and deoxycytidine kinase activity by herpes viruses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Interferon treatment inhibits onset of herpes simplex virus immediate-early transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

The herpes simplex virus virion host shutoff function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

A herpes simplex virus type 1 mutant containing a deletion within immediate early gene 1 is latency-competent in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

The role of herpes simplex virus type 1 thymidine kinase in pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Control of mRNA stability by the virion host shutoff function of herpes simplex virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Transfer of UL41, the gene controlling virion-associated host cell shutoff, between different strains of herpes simplex virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Evidence endogenous interferon production contributed to the lack of ocular virulence of an HSV intertypic recombinant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

Herpes simplex virus type 1 gene UL13 encodes a phosphoprotein that is a component of the virion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

11 July 2018

The role of the UL41 gene of herpes simplex virus type 1 in evasion of non-specific host defence mechanisms during primary infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

25 September 2018

The BglII-N fragment of herpes simplex virus type 2 contains a region responsible for resistance to antiviral effects of interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

25 September 2018

Infected cell protein 22 of herpes simplex virus 1 regulates the expression of virion host shutoff gene U(L)41.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

25 September 2018

Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

25 September 2018

Mapping the genetic region coding for herpes simplex virus resistance to mouse interferon alpha/beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

25 September 2018

Inhibition of transcription of herpes simplex virus immediate early genes in interferon-treated human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=187414

25 September 2018

Type I interferons produced by dendritic cells promote their phenotypic and functional activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12915549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HSV-1 thymidine kinase promotes virulence and latency in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/12915549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.77.17.9337-9345.2003

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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