Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines. (Q35835206)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7853525%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

title

Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines (English)

1 reference

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27 October 2019

author name string

Greenway A

series ordinal

1

1 reference

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27 October 2019

Azad A

series ordinal

2

1 reference

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27 October 2019

McPhee D

series ordinal

3

1 reference

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27 October 2019

language of work or name

English

0 references

publication date

1 March 1995

1 reference

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27 October 2019

1 reference

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27 October 2019

volume

69

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27 October 2019

issue

3

1 reference

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27 October 2019

page(s)

1842-1850

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Functional coupling of the src-family protein tyrosine kinases p59fyn and p53/56lyn with the interleukin 2 receptor: implications for redundancy and pleiotropism in cytokine signal transduction

27 October 2019

cites work

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11 July 2018

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Association of p56lck with IL-2 receptor beta chain is critical for the IL-2-induced activation of p56lck

11 July 2018

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The negative effect of human immunodeficiency virus type 1 Nef on cell surface CD4 expression is not species specific and requires the cytoplasmic domain of CD4.

11 July 2018

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Alternative splicing of human immunodeficiency virus type 1 mRNA modulates viral protein expression, replication, and infectivity.

11 July 2018

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Identification of cellular proteins that bind to the human immunodeficiency virus type 1 nef gene product in vitro: a role for myristylation

11 July 2018

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11 July 2018

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11 July 2018

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Myristoylation-enhanced binding of the HIV-1 Nef protein to T cell skeletal matrix.

11 July 2018

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Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene.

11 July 2018

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Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes

11 July 2018

1 reference

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Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

11 July 2018

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Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo

11 July 2018

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The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

11 July 2018

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Nef 27, but not the Nef 25 isoform of human immunodeficiency virus-type 1 pNL4.3 down-regulates surface CD4 and IL-2R expression in peripheral blood mononuclear cells and transformed T cells

11 July 2018

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Identification of the tyrosine protein kinase from LSTRA cells by use of site-specific antibodies

11 July 2018

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Low and high affinity cellular receptors for interleukin 2. Implications for the level of Tac antigen

11 July 2018

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Cytoplasmic localization of the HTLV-III 3' orf protein in cultured T cells.

11 July 2018

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Effects of mutations within the 3' orf open reading frame region of human T-cell lymphotropic virus type III (HTLV-III/LAV) on replication and cytopathogenicity

11 July 2018

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Oncogene jun encodes a sequence-specific trans-activator similar to AP-1.

11 July 2018

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The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

11 July 2018

1 reference

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Molecular analysis of the interleukin-2 system

11 July 2018

1 reference

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Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity

11 July 2018

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Post-translational alterations of the tyrosine kinase p56lck in response to activators of protein kinase C.

11 July 2018

1 reference

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A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

11 July 2018

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Human immunodeficiency virus type 1 negative factor is a transcriptional silencer

11 July 2018

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11 July 2018

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Differential effects of nef on HIV replication: implications for viral pathogenesis in the host

11 July 2018

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Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis

11 July 2018

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11 July 2018

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11 July 2018

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Functions of the auxiliary gene products of the human immunodeficiency virus type 1.

11 July 2018

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Biochemical and biological comparison of HIV-1 NEF and ras gene products

11 July 2018

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Expression of the type 1 human immunodeficiency virus Nef protein in T cells prevents antigen receptor-mediated induction of interleukin 2 mRNA.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=188795

Interaction of the IL-2 receptor with the src-family kinase p56lck: identification of novel intermolecular association

11 July 2018

1 reference

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

11 July 2018

1 reference

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Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

11 July 2018

1 reference

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T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck

11 July 2018

1 reference

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Genetic characterization of human immunodeficiency virus type 1 nef gene products translated in vitro and expressed in mammalian cells

11 July 2018

1 reference

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CD4, CD8 and the TCR-CD3 complex: a novel class of protein-tyrosine kinase receptor

11 July 2018

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Expression and interactions of the Src family of tyrosine protein kinases in T lymphocytes

11 July 2018

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Regulation of human immunodeficiency virus replication

11 July 2018

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The cytopathic effect of HIV is associated with apoptosis

11 July 2018

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Human immunodeficiency virus type 1 Nef protein inhibits NF-kappa B induction in human T cells

11 July 2018

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Expression of the CD4 gene requires a Myb transcription factor

11 July 2018

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Large-scale production and characterization of recombinant human immunodeficiency virus type 1 Nef.

11 July 2018

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Purification of lymphocytes and platelets by gradient centrifugation

24 September 2018

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The HIV-1 nef protein does not have guanine nucleotide binding, GTPase, or autophosphorylating activities

24 September 2018

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12 December 2020

Characterization of the requirements for human T cell mitogenesis by using suboptimal concentrations of phytohemagglutinin

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The IL-2 receptor beta chain (p70): role in mediating signals for LAK, NK, and proliferative activities

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HIV F/3' orf encodes a phosphorylated GTP-binding protein resembling an oncogene product

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12 December 2020

Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR

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12 December 2020

Lymphocyte activation provokes modification of a lymphocyte-specific protein tyrosine kinase (p56lck)

1 reference

12 December 2020

IL-2 regulation of tyrosine kinase activity is mediated through the p70-75 beta-subunit of the IL-2 receptor

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7853525%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

PubMed publication ID

7853525

1 reference