MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca²⁺ overload and cell death. (Q35858066)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426211%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

MicroRNA-214 protects the mouse heart from ischemic injury by controlling Ca²⁺ overload and cell death (English)

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26 January 2020

1 reference

1 reference

7

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26 January 2020

author name string

Arin B Aurora

1

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26 January 2020

Ahmed I Mahmoud

2

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26 January 2020

Xiang Luo

3

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26 January 2020

Brett A Johnson

4

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26 January 2020

Eva van Rooij

5

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26 January 2020

Satoshi Matsuzaki

6

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26 January 2020

Joseph A Hill

8

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26 January 2020

Rhonda Bassel-Duby

9

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26 January 2020

Hesham A Sadek

10

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26 January 2020

Eric N Olson

11

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26 January 2020

language of work or name

English

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publication date

19 March 2012

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Journal of Clinical Investigation

26 January 2020

published in

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26 January 2020

volume

122

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26 January 2020

issue

4

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26 January 2020

page(s)

1222-1232

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Pervasive roles of microRNAs in cardiovascular biology

26 January 2020

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Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1.

11 July 2018

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11 July 2018

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miR-23a functions downstream of NFATc3 to regulate cardiac hypertrophy

11 July 2018

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Induced overexpression of Na+/Ca2+ exchanger transgene: altered myocyte contractility, [Ca2+]i transients, SR Ca2+ contents, and action potential duration

11 July 2018

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MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice

11 July 2018

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MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20

11 July 2018

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Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes

11 July 2018

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MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes

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miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2

11 July 2018

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MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

11 July 2018

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11 July 2018

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11 July 2018

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Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation

11 July 2018

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11 July 2018

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Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure

11 July 2018

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Hypertrophy and heart failure in mice overexpressing the cardiac sodium-calcium exchanger

11 July 2018

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Regulation of Ncx1 gene expression in the normal and hypertrophic heart

11 July 2018

1 reference

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Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2

11 July 2018

1 reference

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Control of stress-dependent cardiac growth and gene expression by a microRNA

11 July 2018

1 reference

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A phase 1-2 dose-escalating study evaluating the safety and tolerability of istaroxime and specific effects on electrocardiographic and hemodynamic parameters in patients with chronic heart failure with reduced systolic function

11 July 2018

1 reference

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Zebrafish miR-214 modulates Hedgehog signaling to specify muscle cell fate

11 July 2018

1 reference

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A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure

11 July 2018

1 reference

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CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy

11 July 2018

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Calcium, mitochondria and reperfusion injury: a pore way to die.

11 July 2018

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Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

11 July 2018

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Calmodulin kinase signaling in heart: an intriguing candidate target for therapy of myocardial dysfunction and arrhythmias

11 July 2018

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Cellular mechanisms of ischemia-reperfusion injury

11 July 2018

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Altered Na/Ca exchange activity in cardiac hypertrophy and heart failure: a new target for therapy?

11 July 2018

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The mitochondrion in apoptosis: how Pandora's box opens

11 July 2018

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Decoding calcium signals involved in cardiac growth and function

11 July 2018

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Low efficiency of Ca2+ entry through the Na(+)-Ca2+ exchanger as trigger for Ca2+ release from the sarcoplasmic reticulum. A comparison between L-type Ca2+ current and reverse-mode Na(+)-Ca2+ exchange

11 July 2018

1 reference

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The exchanger and cardiac hypertrophy

11 July 2018

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MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling.

11 July 2018

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Cardioprotective effect of vanadyl sulfate on ischemia/reperfusion-induced injury in rat heart in vivo is mediated by activation of protein kinase B and induction of FLICE-inhibitory protein

24 September 2018

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Istaroxime, a stimulator of sarcoplasmic reticulum calcium adenosine triphosphatase isoform 2a activity, as a novel therapeutic approach to heart failure

24 September 2018

1 reference

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Mice overexpressing the cardiac sodium-calcium exchanger: defects in excitation-contraction coupling.

24 September 2018

1 reference

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Overexpression of the cardiac Na+/Ca2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice

24 September 2018

1 reference

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Rapid expression of the Na(+)-Ca2+ exchanger in response to cardiac pressure overload

24 September 2018

1 reference

12 December 2020

Evidence for functional relevance of an enhanced expression of the Na(+)-Ca2+ exchanger in failing human myocardium

1 reference

12 December 2020

Sarcoplasmic reticulum and Na+/Ca2+ exchanger function during early and late relaxation in ventricular myocytes

1 reference

12 December 2020

Calcium/calmodulin-dependent protein kinase II activity is increased in sarcoplasmic reticulum from coronary artery ligated rabbit hearts

1 reference

12 December 2020

Calmodulin kinase II inhibition protects against myocardial cell apoptosis in vivo

1 reference

12 December 2020

CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury

1 reference

12 December 2020

Cytoprotective effect of bis(1-oxy-2-pyridinethiolato)oxovanadiun(IV) on myocardial ischemia/reperfusion injury elicits inhibition of Fas ligand and Bim expression and elevation of FLIP expression

1 reference

12 December 2020

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

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12 December 2020

Identifiers

DOI

10.1172/JCI59327

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426211%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426211%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

22426211

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22426211%20AND%20SRC:MED&resulttype=core&format=json