Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges (Q35894724)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22318495%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

Cytosolic flagellin receptor NLRC4 protects mice against mucosal and systemic challenges (English)

1 reference

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22 January 2020

4

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22 January 2020

author name string

F A Carvalho

1

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22 January 2020

I Nalbantoglu

2

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22 January 2020

J D Aitken

3

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22 January 2020

Y Su

5

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22 January 2020

G H Doho

6

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22 January 2020

M Vijay-Kumar

7

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22 January 2020

A T Gewirtz

8

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22 January 2020

language of work or name

1 reference

8 February 2012

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22 January 2020

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22 January 2020

volume

5

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22 January 2020

issue

3

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22 January 2020

page(s)

288-298

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Molecular mechanisms of inflammasome activation during microbial infections

22 January 2020

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Early MyD88-dependent induction of interleukin-17A expression during Salmonella colitis.

11 July 2018

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TLR5-deficient mice lack basal inflammatory and metabolic defects but exhibit impaired CD4 T cell responses to a flagellated pathogen

11 July 2018

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TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin

11 July 2018

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Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

11 July 2018

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TLR5 activation induces secretory interleukin-1 receptor antagonist (sIL-1Ra) and reduces inflammasome-associated tissue damage

11 July 2018

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The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis

11 July 2018

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Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5

11 July 2018

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Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

11 July 2018

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Latent cytomegalovirus infection exacerbates experimental colitis.

11 July 2018

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The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

11 July 2018

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Toll-like receptor 5-deficient mice have dysregulated intestinal gene expression and nonspecific resistance to Salmonella-induced typhoid-like disease

11 July 2018

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Deletion of TLR5 results in spontaneous colitis in mice

11 July 2018

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TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system

11 July 2018

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Flagellin suppresses epithelial apoptosis and limits disease during enteric infection

11 July 2018

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IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis.

11 July 2018

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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

11 July 2018

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Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

11 July 2018

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Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.

11 July 2018

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Pathophysiological role of Toll-like receptor 5 engagement by bacterial flagellin in colonic inflammation.

11 July 2018

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Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis

11 July 2018

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Generation and characterization of mice transgenic for human IL-18-binding protein isoform a

11 July 2018

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Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host

11 July 2018

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Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression

11 July 2018

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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

11 July 2018

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Mutation of flgM attenuates virulence of Salmonella typhimurium, and mutation of fliA represses the attenuated phenotype

11 July 2018

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Flagella of Salmonella typhimurium are a virulence factor in infected C57BL/6J mice

11 July 2018

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Interleukin-1β (IL-1β) promotes susceptibility of Toll-like receptor 5 (TLR5) deficient mice to colitis.

11 July 2018

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TLR5 is not required for flagellin-mediated exacerbation of DSS colitis

24 September 2018

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24 September 2018

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Dominant-negative TLR5 polymorphism reduces adaptive immune response to flagellin and negatively associates with Crohn's disease

24 September 2018

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Crossref

https://api.crossref.org/works/10.1038%2FMI.2012.8

Activation of toll-like receptor 3 protects against DSS-induced acute colitis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22318495

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22318495

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MI.2012.8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22318495%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22318495%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

22318495

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22318495%20AND%20SRC:MED&resulttype=core&format=json