Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1. (Q35919276)

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scientific article published in March 1998

Language	Label	Description	Also known as
English	Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1.	scientific article published in March 1998

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Cdkn2a, the cyclin-dependent kinase inhibitor encoding p16INK4a and p19ARF, is a candidate for the plasmacytoma susceptibility locus, Pctr1. (English)

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

susceptibility locus

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Zhang S

1

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Ramsay ES

2

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Mock BA

3

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

language of work or name

0 references

publication date

1 March 1998

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Proceedings of the National Academy of Sciences of the United States of America

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

95

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

2429-2434

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

NF-IL6 and NF-kappa B in cytokine gene regulation

1 reference

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11 July 2018

Expression of exogenous NF-IL6 induces apoptosis in Sp2/0-Ag14 myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Homozygous codeletion and differential decreased expression of p15INK4b, p16INK4a-alpha and p16INK4a-beta in mouse lung tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Defective folding of mutant p16(INK4) proteins encoded by tumor-derived alleles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

A novel pre-B acute lymphoblastic leukemia cell line with chromosomal translocation between p16(INK4A)/p15(INK4B) tumor suppressor and immunoglobulin heavy chain genes: TGFbeta/IL-7 inhibitory signaling mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Tumor suppressor p16INK4A: structural characterization of wild-type and mutant proteins by NMR and circular dichroism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6

1 reference

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Mammalian G1 cyclins

1 reference

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Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit

1 reference

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11 July 2018

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

The cell cycle and the retinoblastoma protein family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

D-type cyclin-dependent kinase activity in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Germline p16 mutations in familial melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Transcriptional repression of the D-type cyclin-dependent kinase inhibitor p16 by the retinoblastoma susceptibility gene product pRb.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Interleukin 6 is essential for in vivo development of B lineage neoplasms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

The retinoblastoma protein and cell cycle control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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Genomic structure, expression and mutational analysis of the P15 (MTS2) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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Cloning and characterization of murine p16INK4a and p15INK4b genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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A macrophage-derived factor required by plasmacytomas for survival and proliferation in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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Rapid induction of IgM-secreting murine plasmacytomas by pristane and an immunoglobulin heavy-chain promoter/enhancer-driven c-myc/v-Ha-ras retrovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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A mouse homeo box gene, Hox-1.5, and the morphological locus, Hd, map to within 1 cM on chromosome 6

1 reference

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

The murine Il-6 gene maps to the proximal region of chromosome 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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The E2F transcription factor is a cellular target for the RB protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle

1 reference

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Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product

1 reference

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Plasmacytomagenesis in mice: model of neoplastic development dependent upon chromosomal translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

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Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

11 July 2018

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

27 July 2018

Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

24 September 2018

Role of the INK4a locus in tumor suppression and cell mortality.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

24 September 2018

Mutations associated with familial melanoma impair p16INK4 function.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=19364

24 September 2018

The genetics of susceptibility to RIM-induced plasmacytomagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent hypermethylation of p16 and p15 genes in multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of the CDKN2 (MTS1/p16ink4A) gene in primary B-cell lymphomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and mapping of four new DNA markers from mouse chromosome 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The plasmacytoma resistance gene, Pctr2, delays the onset of tumorigenesis and resides in the telomeric region of chromosome 4

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of cell cycle arrest and B cell terminal differentiation by CDK inhibitor p18(INK4c) and IL-6

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homozygous deletion of mouse homolog of p16/CDKN2 gene on chromosome 4 in mouse liver epithelial cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ins and outs of RB: coupling gene expression to the cell cycle clock

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasmacytoma development in mice injected with silicone gels

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of two genes on chromosome 4 that determine resistance to plasmacytoma induction in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/9482902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.95.5.2429

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

1998PNAS...95.2429Z

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

ResearchGate publication ID

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