Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates (Q35933396)

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scientific article published on November 1, 1991

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English	Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates	scientific article published on November 1, 1991

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11 August 2017

Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates (English)

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11 August 2017

phosphorylation

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E. A. Nigg

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22 October 2022

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W. Krek

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22 October 2022

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1 November 1991

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22 October 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/1655418/?tool=EBI

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22 October 2022

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22 October 2022

https://europepmc.org/articles/PMC453060?pdf=render

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22 October 2022

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fj.1460-2075.1991.tb04897.x

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10.1002/J.1460-2075.1991.TB04897.X

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http://onlinelibrary.wiley.com/wol1/doi/10.1002/j.1460-2075.1991.tb04897.x/fullpdf

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10.1002/J.1460-2075.1991.TB04897.X

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22 October 2022

The EMBO Journal

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3331-3341

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Europe PubMed Central

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11 August 2017

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Unraveling of mitotic control mechanisms

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Negative regulation of mitosis by wee1+, a gene encoding a protein kinase homolog

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p34cdc2 is located in both nucleus and cytoplasm; part is centrosomally associated at G2/M and enters vesicles at anaphase

1 reference

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Structure and developmental expression of the chicken CDC2 kinase

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Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

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Mitotic control by metaphase-promoting factor and cdc proteins

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Maturation promoting factor, cyclin and the control of M-phase

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Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1 reference

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Cyclin synthesis drives the early embryonic cell cycle

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Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase

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The role of cyclin synthesis, modification and destruction in the control of cell division.

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2 October 2017

Substrates for p34cdc2: in vivo veritas?

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2 October 2017

p34cdc2: the S and M kinase?

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Cell cycle control in eukaryotes: molecular mechanisms of cdc2 activation

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Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.

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Control of M-phase by maturation-promoting factor

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Universal control mechanism regulating onset of M-phase

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Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites

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Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

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Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase

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cdc25+ functions as an inducer in the mitotic control of fission yeast

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/1655418

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1 reference

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inferred from PubMed ID database lookup

Regulation of p34cdc2 protein kinase during mitosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/1655418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular localisation and expression of mammalian CDC2 protein during myogenic differentiation

1 reference

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Purification of MPF from starfish: identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation

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Regulation of mitosis by cyclic accumulation of p80 cdc25 mitotic inducer in fission yeast

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Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication

1 reference

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The fission yeast cdc2/cdc13/suc1 protein kinase: regulation of catalytic activity and nuclear localization

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/J.1460-2075.1991.TB04897.X

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1655418

22 October 2022

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

11 August 2017

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