Insulin signaling in heart muscle: lessons from genetically engineered mouse models. (Q35940001)

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4 January 2020

review article

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title

Insulin signaling in heart muscle: lessons from genetically engineered mouse models (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15527684%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15527684%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

author name string

E Dale Abel

series ordinal

1

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11 August 2017

publication date

1 December 2004

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15527684%20AND%20SRC:MED&resulttype=core&format=json

Current Hypertension Reports

4 January 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15527684%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

volume

6

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4 January 2020

issue

6

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4 January 2020

page(s)

416-423

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15527684%20AND%20SRC:MED&resulttype=core&format=json

Tissue-specific regulation of protein synthesis by insulin and free fatty acids

4 January 2020

cites work

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https://api.crossref.org/works/10.1007%2FS11906-004-0034-4

Starvation and diabetes increase the amount of pyruvate dehydrogenase kinase isoenzyme 4 in rat heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-004-0034-4

Reperfusion-activated Akt kinase prevents apoptosis in transgenic mouse hearts overexpressing insulin-like growth factor-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-004-0034-4

Caveolin-1 null mice develop cardiac hypertrophy with hyperactivation of p42/44 MAP kinase in cardiac fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-004-0034-4

Caveolin-1/3 double-knockout mice are viable, but lack both muscle and non-muscle caveolae, and develop a severe cardiomyopathic phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-004-0034-4

Caveolin-1-deficient mice show insulin resistance and defective insulin receptor protein expression in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-004-0034-4

Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-004-0034-4

Differential effects of rosiglitazone and metformin on adipose tissue distribution and glucose uptake in type 2 diabetic subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11906-004-0034-4

Preservation of glucose metabolism in hypertrophic GLUT4-null hearts

21 January 2018

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12 December 2020

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

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12 December 2020

Mechanism of enhanced cardiac function in mice with hypertrophy induced by overexpressed Akt.

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12 December 2020

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

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12 December 2020

Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia

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12 December 2020

Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction

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12 December 2020

The lipid phosphatase SHIP2 controls insulin sensitivity

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12 December 2020

An increase in the myocardial PCr/ATP ratio in GLUT4 null mice

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12 December 2020

Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

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12 December 2020

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

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12 December 2020

Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways

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12 December 2020

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

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12 December 2020

Akt signaling mediates postnatal heart growth in response to insulin and nutritional status

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12 December 2020

Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling

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12 December 2020

Cardiac hypertrophy with preserved contractile function after selective deletion of GLUT4 from the heart

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12 December 2020

Minimally invasive aortic banding in mice: effects of altered cardiomyocyte insulin signaling during pressure overload

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12 December 2020

IRS-2 pathways integrate female reproduction and energy homeostasis

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12 December 2020

Regulation of insulin-responsive aminopeptidase expression and targeting in the insulin-responsive vesicle compartment of glucose transporter isoform 4-deficient cardiomyocytes.

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12 December 2020

Adaptation and maladaptation of the heart in diabetes: Part I: general concepts

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12 December 2020

Insulin Signaling in Microdomains of the Plasma Membrane

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12 December 2020

Insulin-like growth factor I as a cardiac hormone: physiological and pathophysiological implications in heart disease

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12 December 2020

The conserved phosphoinositide 3-kinase pathway determines heart size in mice

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12 December 2020

Transcriptional effects of chronic Akt activation in the heart.

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12 December 2020

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

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12 December 2020

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

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12 December 2020

Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice

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12 December 2020

Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

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12 December 2020

Myocardial protection by insulin at reperfusion requires early administration and is mediated via Akt and p70s6 kinase cell-survival signaling

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12 December 2020

Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation

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12 December 2020

Phosphoinositide 3-kinase(p110α) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy

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12 December 2020

Altered thymic positive selection and intracellular signals in Cbl-deficient mice

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12 December 2020

Phenotypic spectrum caused by transgenic overexpression of activated Akt in the heart

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12 December 2020

Glucose transport in the heart

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12 December 2020

Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis

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12 December 2020

Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85 alpha

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12 December 2020

The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway

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12 December 2020

Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

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12 December 2020

Altered metabolism causes cardiac dysfunction in perfused hearts from diabetic (db/db) mice

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12 December 2020

Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade

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12 December 2020

Mice deficient in the insulin-regulated membrane aminopeptidase show substantial decreases in glucose transporter GLUT4 levels but maintain normal glucose homeostasis

1 reference

12 December 2020

A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated wi

1 reference

12 December 2020

Akt/protein kinase B promotes organ growth in transgenic mice

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12 December 2020

10.1007/S11906-004-0034-4

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15527684%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

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