Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells (Q35953952)

11 August 2017

Cannabinoids Regulate Bcl-2 and Cyclin D2 Expression in Pancreatic β Cells (English)

1 reference

11 August 2017

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8

Josephine M Egan

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11 August 2017

Jihye Kim

1

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11 August 2017

Kyung Jin Lee

2

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11 August 2017

Jung Seok Kim

3

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11 August 2017

Jun Gi Rho

4

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11 August 2017

Jung Jae Shin

5

1 reference

11 August 2017

Woo Keun Song

6

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11 August 2017

Eun Kyung Lee

7

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11 August 2017

Wook Kim

9

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11 August 2017

language of work or name

English

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publication date

11 March 2016

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11 August 2017

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11 August 2017

11

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11 August 2017

3

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11 August 2017

e0150981

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Creative Commons CC0 License

11 August 2017

start time

11 March 2016

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4788443/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Blockade of cannabinoid 1 receptor improves GLP-1R mediated insulin secretion in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Cannabinoids induce pancreatic β-cell death by directly inhibiting insulin receptor activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Bcl-2 proteins in diabetes: mitochondrial pathways of β-cell death and dysfunction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Cannabinoids inhibit insulin receptor signaling in pancreatic β-cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Cannabinoid receptor agonist-induced apoptosis of human prostate cancer cells LNCaP proceeds through sustained activation of ERK1/2 leading to G1 cell cycle arrest

2 October 2017

1 reference

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Cannabinoid receptors as novel targets for the treatment of melanoma

2 October 2017

1 reference

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p16INK4a induces an age-dependent decline in islet regenerative potential

2 October 2017

1 reference

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Insulin resistance and pancreatic beta cell failure

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.

2 October 2017

1 reference

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PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

2 October 2017

1 reference

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AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Disruption of IRS-2 causes type 2 diabetes in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

2 October 2017

1 reference

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Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: inhibition by Bcl-2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Cannabinoid receptor as a novel target for the treatment of prostate cancer

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4788443

10.1371/JOURNAL.PONE.0150981

24 September 2018

Identifiers

DOI

1 reference

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

26967640

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