Akt blocks the tumor suppressor activity of LKB1 by promoting phosphorylation-dependent nuclear retention through 14-3-3 proteins. (Q35964171)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22611470%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Akt blocks the tumor suppressor activity of LKB1 by promoting phosphorylation-dependent nuclear retention through 14-3-3 proteins (English)

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1 February 2020

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3

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1 February 2020

author name string

Ling Liu

1

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1 February 2020

Fung-Ming Siu

2

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1 February 2020

Aimin Xu

4

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1 February 2020

Yu Wang

5

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1 February 2020

language of work or name

English

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publication date

10 April 2012

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American Journal of Translational Research

1 February 2020

published in

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volume

4

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issue

2

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page(s)

175-186

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describes a project that uses

1 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3353533/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

2 October 2017

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2 October 2017

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Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

2 October 2017

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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

2 October 2017

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Integrated Molecular and Clinical Analysis of AKT Activation in Metastatic Melanoma

2 October 2017

1 reference

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AKT can be activated in the nucleus.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3353533

Growth and molecular profile of lung cancer cells expressing ectopic LKB1: down-regulation of the phosphatidylinositol 3'-phosphate kinase/PTEN pathway.

24 September 2018

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24 September 2018

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22611470%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

22611470

1 reference