Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons (Q35987121)

11 August 2017

Intranuclear matrix metalloproteinases promote DNA damage and apoptosis induced by oxygen-glucose deprivation in neurons (English)

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11 August 2017

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J W Hill

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R Poddar

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J F Thompson

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G A Rosenberg

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Y Yang

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language of work or name

English

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publication date

16 June 2012

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220

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277-290

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describes a project that uses

11 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4546359/fullTextXML

inferred from PubMed Central ID database lookup

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Matrix metalloproteinases are associated with increased blood-brain barrier opening in vascular cognitive impairment

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Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activator

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Increased intranuclear matrix metalloproteinase activity in neurons interferes with oxidative DNA repair in focal cerebral ischemia.

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Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia

2 October 2017

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A novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells

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2 October 2017

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Phosphorylation of human oxoguanine DNA glycosylase (alpha-OGG1) modulates its function

2 October 2017

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2 October 2017

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Matrix metalloproteinase inhibition prevents oxidative stress-associated blood-brain barrier disruption after transient focal cerebral ischemia

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2 October 2017

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Post-ischemic brain damage: targeting PARP-1 within the ischemic neurovascular units as a realistic avenue to stroke treatment

11 July 2018

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Systemic inflammation alters the kinetics of cerebrovascular tight junction disruption after experimental stroke in mice.

11 July 2018

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Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 reduces infarct size

11 July 2018

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Matrix metalloproteinase-13 is activated and is found in the nucleus of neural cells after cerebral ischemia.

11 July 2018

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Microglia cells protect neurons by direct engulfment of invading neutrophil granulocytes: a new mechanism of CNS immune privilege

24 September 2018

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24 September 2018

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Critical role of calpain I in mitochondrial release of apoptosis-inducing factor in ischemic neuronal injury.

24 September 2018

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Early upregulation of matrix metalloproteinases following reperfusion triggers neuroinflammatory mediators in brain ischemia in rat.

24 September 2018

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Impaired DNA repair via the base-excision repair pathway after focal ischemic brain injury: a protein phosphorylation-dependent mechanism reversed by hypothermic neuroprotection

24 September 2018

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Matrix metalloproteinase 3 is present in the cell nucleus and is involved in apoptosis.

24 September 2018

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Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat.

24 September 2018

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Role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546359

A highly specific inhibitor of matrix metalloproteinase-9 rescues laminin from proteolysis and neurons from apoptosis in transient focal cerebral ischemia.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546359

Poly(ADP-ribose) polymerase-1 promotes microglial activation, proliferation, and matrix metalloproteinase-9-mediated neuron death

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546359

Minocycline protects against permanent cerebral ischemia in wild type but not in matrix metalloprotease-9-deficient mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546359

Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546359

Role for matrix metalloproteinase 9 after focal cerebral ischemia: effects of gene knockout and enzyme inhibition with BB-94.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546359

Matrix metalloproteinase-2 (MMP-2) is present in the nucleus of cardiac myocytes and is capable of cleaving poly (ADP-ribose) polymerase (PARP) in vitro

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22710064

12 December 2020

inferred from PubMed ID database lookup

Trafficking and secretion of matrix metalloproteinase-2 in olfactory ensheathing glial cells: A role in cell migration?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22710064

12 December 2020

inferred from PubMed ID database lookup

Early decrease of XRCC1, a DNA base excision repair protein, may contribute to DNA fragmentation after transient focal cerebral ischemia in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22710064

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.NEUROSCIENCE.2012.06.019

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22710064

1 reference