Trans-cellular propagation of Tau aggregation by fibrillar species (Q36003836)

11 August 2017

Trans-cellular propagation of Tau aggregation by fibrillar species (English)

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11 August 2017

4

David M Holtzman

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11 August 2017

Najla Kfoury

1

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11 August 2017

Brandon B Holmes

series ordinal

2

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11 August 2017

Hong Jiang

series ordinal

3

1 reference

11 August 2017

Marc I Diamond

series ordinal

5

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11 August 2017

language of work or name

English

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publication date

29 March 2012

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Journal of Biological Chemistry

11 August 2017

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11 August 2017

287

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11 August 2017

23

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11 August 2017

19440-19451

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describes a project that uses

11 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3365982/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice

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2 October 2017

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Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain

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Seeding of normal Tau by pathological Tau conformers drives pathogenesis of Alzheimer-like tangles

2 October 2017

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α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells

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Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model

2 October 2017

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Heat‐shock protein 70 modulates toxic extracellular α‐synuclein oligomers and rescues trans‐synaptic toxicity

2 October 2017

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Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies

2 October 2017

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Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells

2 October 2017

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Neurodegenerative diseases target large-scale human brain networks

2 October 2017

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Propagation of tau misfolding from the outside to the inside of a cell.

2 October 2017

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2 October 2017

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Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates

2 October 2017

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Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease

2 October 2017

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ROCK and PRK-2 mediate the inhibitory effect of Y-27632 on polyglutamine aggregation

2 October 2017

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Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

2 October 2017

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Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

2 October 2017

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The role of exosomes in the processing of proteins associated with neurodegenerative diseases

2 October 2017

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Induction of tau pathology by intracerebral infusion of amyloid-beta -containing brain extract and by amyloid-beta deposition in APP x Tau transgenic mice

2 October 2017

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Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.

2 October 2017

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Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

2 October 2017

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Biologically active molecules that reduce polyglutamine aggregation and toxicity

2 October 2017

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Prions and exosomes: from PrPc trafficking to PrPsc propagation

2 October 2017

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Distinct FTDP-17 missense mutations in tau produce tau aggregates and other pathological phenotypes in transfected CHO cells

2 October 2017

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X-34, a fluorescent derivative of Congo red: a novel histochemical stain for Alzheimer's disease pathology.

2 October 2017

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

2 October 2017

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Staging of Alzheimer's disease-related neurofibrillary changes

2 October 2017

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Prions tunnel between cells

2 October 2017

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Transplanted dopaminergic neurons develop PD pathologic changes: a second case report

23 September 2018

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The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365982

Effects of alpha-synuclein immunization in a mouse model of Parkinson's disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365982

Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease.

23 September 2018

1 reference

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A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365982

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365982

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3365982

23 September 2018

Identifiers

DOI

10.1074/JBC.M112.346072

1 reference

11 August 2017

1 reference

11 August 2017

PubMed publication ID

22461630

1 reference