Regulatory T cells and intestinal homeostasis (Q36079900)

12 August 2017

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title

Regulatory T cells and intestinal homeostasis (English)

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12 August 2017

1

Janine L Coombes

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12 August 2017

5

Fiona Powrie

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12 August 2017

Nicholas J Robinson

2

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12 August 2017

Kevin J Maloy

series ordinal

3

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12 August 2017

Holm H Uhlig

series ordinal

4

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12 August 2017

language of work or name

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1 April 2005

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12 August 2017

published in

Immunological Reviews

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12 August 2017

volume

204

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12 August 2017

page(s)

184-194

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The immunological and genetic basis of inflammatory bowel disease

12 August 2017

cites work

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Animal models of mucosal inflammation and their relation to human inflammatory bowel disease

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CD4+ T cells that express high levels of CD45RB induce wasting disease when transferred into congenic severe combined immunodeficient mice. Disease development is prevented by cotransfer of purified CD4+ T cells

21 January 2018

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Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

21 January 2018

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T cell-mediated pathology in two models of experimental colitis depends predominantly on the interleukin 12/Signal transducer and activator of transcription (Stat)-4 pathway, but is not conditional on interferon gamma expression by T cells

21 January 2018

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INDIGENOUS, NORMAL, AND AUTOCHTHONOUS FLORA OF THE GASTROINTESTINAL TRACT

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Analysis of 16S libraries of mouse gastrointestinal microflora reveals a large new group of mouse intestinal bacteria.

21 January 2018

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Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis

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CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

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An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

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Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4+ regulatory T cells and IL-10.

21 January 2018

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21 January 2018

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21 January 2018

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CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

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CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

21 January 2018

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Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

21 January 2018

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

21 January 2018

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

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Control of regulatory T cell development by the transcription factor Foxp3

21 January 2018

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants

21 January 2018

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Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

21 January 2018

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Interleukin-10-deficient mice develop chronic enterocolitis

21 January 2018

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Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.

21 January 2018

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Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

21 January 2018

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A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

21 January 2018

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Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

21 January 2018

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CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

21 January 2018

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TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

21 January 2018

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Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

21 January 2018

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Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

21 January 2018

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In vivo dynamics of antigen-specific regulatory T cells not predicted from behavior in vitro

21 January 2018

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Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo

21 January 2018

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Continuous activation of autoreactive CD4+ CD25+ regulatory T cells in the steady state.

21 January 2018

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T cell homeostasis and systemic autoimmunity

21 January 2018

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Homeostatic expansion of T cells during immune insufficiency generates autoimmunity.

21 January 2018

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T cell regulation as a side effect of homeostasis and competition

21 January 2018

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Peripheral selection of T cell repertoires: the role of continuous thymus output

21 January 2018

1 reference

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10.1111/J.0105-2896.2005.00250.X

21 January 2018

Identifiers

DOI

1 reference

12 August 2017

1 reference