Dendritic cells as therapeutic vaccines against cancer (Q36085614)

12 August 2017

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title

Dendritic cells as therapeutic vaccines against cancer (English)

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12 August 2017

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1

Jacques Banchereau

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12 August 2017

A Karolina Palucka

2

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12 August 2017

publication date

1 April 2005

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Nature Reviews Immunology

12 August 2017

published in

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12 August 2017

volume

5

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12 August 2017

issue

4

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12 August 2017

page(s)

296-306

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The dendritic cell system and its role in immunogenicity

12 August 2017

cites work

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

21 January 2018

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Mouse and human dendritic cell subtypes

21 January 2018

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CD34+ hematopoietic progenitors from human cord blood differentiate along two independent dendritic cell pathways in response to GM-CSF+TNF alpha

21 January 2018

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The nature of the principal type 1 interferon-producing cells in human blood

21 January 2018

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Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

21 January 2018

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Natural interferon alpha/beta-producing cells link innate and adaptive immunity

21 January 2018

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Activation of influenza virus-specific CD4+ and CD8+ T cells: a new role for plasmacytoid dendritic cells in adaptive immunity

21 January 2018

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IL-6 switches the differentiation of monocytes from dendritic cells to macrophages

21 January 2018

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Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice.

21 January 2018

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Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

21 January 2018

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TNF skews monocyte differentiation from macrophages to dendritic cells

21 January 2018

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Interleukin 15 skews monocyte differentiation into dendritic cells with features of Langerhans cells

21 January 2018

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An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.

21 January 2018

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CD8alpha+ and CD8alpha- subclasses of dendritic cells direct the development of distinct T helper cells in vivo

21 January 2018

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Distinct dendritic cell subsets differentially regulate the class of immune response in vivo

21 January 2018

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Lipopolysaccharides from distinct pathogens induce different classes of immune responses in vivo

21 January 2018

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Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

21 January 2018

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Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells

21 January 2018

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Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

21 January 2018

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In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination

21 January 2018

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Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

21 January 2018

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Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma

21 January 2018

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Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells

21 January 2018

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Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells

21 January 2018

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Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy

21 January 2018

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Dendritic cell immunotherapy: mapping the way.

21 January 2018

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A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection.

21 January 2018

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Rapid induction of tumor-specific type 1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells.

21 January 2018

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Dendritic cells as sensors of infection.

21 January 2018

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Toll-dependent control mechanisms of CD4 T cell activation.

21 January 2018

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Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity

21 January 2018

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Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

21 January 2018

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Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming

21 January 2018

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Prostaglandin E2 is a key factor for CCR7 surface expression and migration of monocyte-derived dendritic cells

21 January 2018

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Functionally distinct dendritic cell (DC) populations induced by physiologic stimuli: prostaglandin E(2) regulates the migratory capacity of specific DC subsets

21 January 2018

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Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells

21 January 2018

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Route of immunization with peptide-pulsed dendritic cells controls the distribution of memory and effector T cells in lymphoid tissues and determines the pattern of regional tumor control

21 January 2018

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Expansion of melanoma-specific cytolytic CD8+ T cell precursors in patients with metastatic melanoma vaccinated with CD34+ progenitor-derived dendritic cells

21 January 2018

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Preferential localization of effector memory cells in nonlymphoid tissue

21 January 2018

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Effector and memory T-cell differentiation: implications for vaccine development

21 January 2018

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On natural and artificial vaccinations

21 January 2018

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Viral immune evasion due to persistence of activated T cells without effector function

21 January 2018

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Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

21 January 2018

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Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen

21 January 2018

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T-lymphocyte response to cytochrome c. I. Demonstration of a T-cell heteroclitic proliferative response and identification of a topographic antigenic determinant on pigeon cytochrome c whose immune recognition requires two complementing major histoc

21 January 2018

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Diversity and recognition efficiency of T cell responses to cancer

21 January 2018

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Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

21 January 2018

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Cancer immunotherapy using gene-modified dendritic cells.

21 January 2018

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Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo

21 January 2018

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Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization

21 January 2018

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Dendritic cells in cancer immunotherapy

21 January 2018

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Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

21 January 2018

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Cross-priming of naive CD8 T cells against melanoma antigens using dendritic cells loaded with killed allogeneic melanoma cells.

21 January 2018

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Dendritic cells loaded with killed breast cancer cells induce differentiation of tumor-specific cytotoxic T lymphocytes

21 January 2018

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

21 January 2018

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

21 January 2018

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Type 1 T regulatory cells.

21 January 2018

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Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

21 January 2018

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Foxp3 expressing CD4+CD25(high) regulatory T cells are overrepresented in human metastatic melanoma lymph nodes and inhibit the function of infiltrating T cells

21 January 2018

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Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy

21 January 2018

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Anti-tumor T cell response and protective immunity in mice that received sublethal irradiation and immune reconstitution.

21 January 2018

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Tumor lysate-pulsed dendritic cells can elicit an effective antitumor immune response during early lymphoid recovery

21 January 2018

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Cancer immunotherapy: breaking the barriers to harvest the crop

21 January 2018

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Mechanisms and functional significance of tumour-induced dendritic-cell defects

21 January 2018

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Type I interferons keep activated T cells alive

21 January 2018

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Stimulation of naïve and memory T cells by cytokines

21 January 2018

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T-cell-directed cancer vaccines: mechanisms of immune escape and immune tolerance

21 January 2018

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Regulation of T cell immunity by dendritic cells

21 January 2018

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The biology of chemokines and their receptors

21 January 2018

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Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

21 January 2018

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Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

21 January 2018

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CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

21 January 2018

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CD8+ T-cell memory: only the good ones last

21 January 2018

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Toward an understanding of NKT cell biology: progress and paradoxes

21 January 2018

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Natural killer cells, viruses and cancer

21 January 2018

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B cells inhibit induction of T cell-dependent tumor immunity.

21 January 2018

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C-type lectin receptors on dendritic cells and Langerhans cells

21 January 2018

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Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules

21 January 2018

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BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood

21 January 2018

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BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction

21 January 2018

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Tumor-specific killer cells in paraneoplastic cerebellar degeneration

21 January 2018

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Dendritic cells pulsed with protein antigens in vitro can prime antigen-specific, MHC-restricted T cells in situ

21 January 2018

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Antigen-pulsed dendritic cells can efficiently induce an antibody response in vivo

21 January 2018

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Therapy of murine tumors with tumor peptide-pulsed dendritic cells: dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines

21 January 2018

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Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity

21 January 2018

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Costimulatory molecule-deficient dendritic cell progenitors (MHC class II+, CD80dim, CD86-) prolong cardiac allograft survival in nonimmunosuppressed recipients

21 January 2018

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Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.

21 January 2018

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Phase 2 trial of vaccination with tyrosinase peptides and granulocyte-macrophage colony-stimulating factor in patients with metastatic melanoma.

21 January 2018

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Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

21 January 2018

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Phase I trial of large multivalent immunogen derived from melanoma lysates in patients with disseminated melanoma

21 January 2018

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GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells

21 January 2018

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Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo

21 January 2018

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Cytotoxic T cells recognize fragments of the influenza nucleoprotein

31 March 2020

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31 March 2020

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Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo

31 March 2020

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Signals required for differentiating dendritic cells from human monocytes in vitro

31 March 2020

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Interferon-alpha and granulocyte-macrophage colony-stimulating factor differentiate peripheral blood monocytes into potent antigen-presenting cells

31 March 2020

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Reciprocal control of T helper cell and dendritic cell differentiation

31 March 2020

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The role of dendritic cells in T cell selection and survival

31 March 2020

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Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells

31 March 2020

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Pro-inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum-free conditions

31 March 2020

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alpha-type-1 polarized dendritic cells: a novel immunization tool with optimized CTL-inducing activity

31 March 2020

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Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation

31 March 2020

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Dendritic cells injected via different routes induce immunity in cancer patients

31 March 2020

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Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma

31 March 2020

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Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

31 March 2020

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NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway

31 March 2020

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Reciprocal regulation of polarized cytokine production by effector B and T cells

31 March 2020

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The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface

31 March 2020

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Regression of tumors in mice vaccinated with professional antigen-presenting cells pulsed with tumor extracts

31 March 2020

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Phase I/II study of treatment with dendritic cell vaccines in patients with disseminated melanoma

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1592

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Dimensions Publication ID

12 August 2017

1010707228

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