Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1(-/-) mice fed low levels of cholic acid (Q36114905)

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English	Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1(-/-) mice fed low levels of cholic acid	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Delineation of biochemical, molecular, and physiological changes accompanying bile acid pool size restoration in Cyp7a1(-/-) mice fed low levels of cholic acid (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Ryan D Jones

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Joyce J Repa

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

David W Russell

3

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

John M Dietschy

4

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Europe PubMed Central

PMC publication ID

12 August 2017

Stephen D Turley

5

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Europe PubMed Central

PMC publication ID

12 August 2017

publication date

24 May 2012

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Europe PubMed Central

PMC publication ID

12 August 2017

American Journal of Physiology - Gastrointestinal and Liver Physiology

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Europe PubMed Central

PMC publication ID

12 August 2017

303

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

2

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

G263-74

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity

1 reference

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Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

1 reference

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Disruption of the murine protein kinase Cbeta gene promotes gallstone formation and alters biliary lipid and hepatic cholesterol metabolism

1 reference

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Deciphering the nuclear bile acid receptor FXR paradigm

1 reference

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2 October 2017

Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters

1 reference

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2 October 2017

Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.

1 reference

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2 October 2017

Multiple mechanisms limit the accumulation of unesterified cholesterol in the small intestine of mice deficient in both ACAT2 and ABCA1.

1 reference

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Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice

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2 October 2017

Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice

1 reference

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Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge

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Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration

1 reference

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2 October 2017

Bile acid transporters

1 reference

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Bile acids: regulation of apoptosis by ursodeoxycholic acid

1 reference

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2 October 2017

Bile acids as regulatory molecules

1 reference

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2 October 2017

Bile acids: regulation of synthesis

1 reference

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2 October 2017

Cholesterol feeding prevents hepatic accumulation of bile acids in cholic acid-fed farnesoid X receptor (FXR)-null mice: FXR-independent suppression of intestinal bile acid absorption

1 reference

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2 October 2017

Fifty years of advances in bile acid synthesis and metabolism

1 reference

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2 October 2017

Hepatic insulin resistance directly promotes formation of cholesterol gallstones

1 reference

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2 October 2017

Regulation of hepatic bile acid transporters Ntcp and Bsep expression

1 reference

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2 October 2017

Bile acid transporters: structure, function, regulation and pathophysiological implications

1 reference

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2 October 2017

Enzymes in the conversion of cholesterol into bile acids.

1 reference

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2 October 2017

Clinical utility of bile acid sequestrants in the treatment of dyslipidemia: a scientific review

1 reference

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Micellar solubilisation of cholesterol is essential for absorption in humans.

1 reference

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2 October 2017

Quantitative real-time polymerase chain reaction measurement of regulators of G-protein signaling mRNA levels in mouse tissues

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2 October 2017

Rodent husbandry and care

1 reference

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Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor

1 reference

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2 October 2017

Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

1 reference

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Elevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4

1 reference

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cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain

1 reference

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Identification and characterization of a mouse oxysterol 7alpha-hydroxylase cDNA.

1 reference

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2 October 2017

Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.

1 reference

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Inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase by mevinolin in familial hypercholesterolemia heterozygotes: effects on cholesterol balance

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Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets

1 reference

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Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation.

1 reference

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Validation of a dual-isotope plasma ratio method for measurement of cholesterol absorption in rats

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Pravastatin lowers serum cholesterol, cholesterol-precursor sterols, fecal steroids, and cholesterol absorption in man

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Intestinal FXR-mediated FGF15 production contributes to diurnal control of hepatic bile acid synthesis in mice

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Prevention and treatment of obesity, insulin resistance, and diabetes by bile acid-binding resin.

1 reference

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Feeding natural hydrophilic bile acids inhibits intestinal cholesterol absorption: studies in the gallstone-susceptible mouse

1 reference

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Hypercholesterolemia and changes in lipid and bile acid metabolism in male and female cyp7A1-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404571

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Measurement of intestinal cholesterol absorption by plasma and fecal dual-isotope ratio, mass balance, and lymph fistula methods in the mouse: an analysis of direct versus indirect methodologies

1 reference

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Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3404571

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Alternate pathways of bile acid synthesis in the cholesterol 7alpha-hydroxylase knockout mouse are not upregulated by either cholesterol or cholestyramine feeding.

1 reference

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Altered bile acid metabolism in nonobese, spontaneously diabetic (NOD) mice.

1 reference

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The absorption of cholesterol and the sterol balance in the Tarahumara Indians of Mexico fed cholesterol-free and high cholesterol diets

1 reference

https://pubmed.ncbi.nlm.nih.gov/22628034

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based on heuristic

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Dietary Cholesterol and Type of Fat Differentially Affect Cholesterol Metabolism and Atherosclerosis in Baboons

1 reference

https://pubmed.ncbi.nlm.nih.gov/22628034

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22628034

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Serum concentration of 7 alpha-hydroxycholesterol as an indicator of bile acid synthesis in humans

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Regulation of fecal bile acid excretion in male golden Syrian hamsters fed a cereal-based diet with and without added cholesterol

1 reference

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Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22628034

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based on heuristic

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Centripetal cholesterol flow from the extrahepatic organs through the liver is normal in mice with mutated Niemann-Pick type C protein (NPC1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22628034

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based on heuristic

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Quantitative aspects of the intestinal absorption and metabolism of cholesterol and beta-sitosterol in the rat

1 reference

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https://pubmed.ncbi.nlm.nih.gov/22628034

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1 reference

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Identifiers

10.1152/AJPGI.00111.2012

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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