Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis (Q36119681)

12 August 2017

Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis (English)

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12 August 2017

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12

Jeffrey D Esko

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12 August 2017

10

Richard L Gallo

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12 August 2017

Mark M Fuster

1

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12 August 2017

Lianchun Wang

2

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12 August 2017

Janice Castagnola

3

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12 August 2017

Lyudmila Sikora

4

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12 August 2017

Krisanavane Reddi

5

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12 August 2017

Phillip H A Lee

6

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12 August 2017

Katherine A Radek

7

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12 August 2017

Manuela Schuksz

8

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12 August 2017

Joseph R Bishop

9

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12 August 2017

P Sriramarao

11

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12 August 2017

language of work or name

English

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publication date

30 April 2007

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12 August 2017

11

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inferred from page(s)

published in

Journal of Cell Biology

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12 August 2017

177

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12 August 2017

3

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12 August 2017

539-549

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describes a project that uses

12 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2064806/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Mice deficient in Ext2 lack heparan sulfate and develop exostoses

2 October 2017

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Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function

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A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer

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Heparan sulfates expressed in the distal lung are required for Fgf10 binding to the epithelium and for airway branching

2 October 2017

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Molecular regulation of vessel maturation

2 October 2017

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Order out of chaos: assembly of ligand binding sites in heparan sulfate

2 October 2017

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Mammalian heparanase: involvement in cancer metastasis, angiogenesis and normal development

2 October 2017

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Lack of collagen XVIII/endostatin results in eye abnormalities

2 October 2017

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Impaired recruitment of bone-marrow-derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

2 October 2017

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Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

2 October 2017

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VEGF-VEGF receptor complexes as markers of tumor vascular endothelium

2 October 2017

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Characterization of a novel EGFP reporter mouse to monitor Cre recombination as demonstrated by a Tie2 Cre mouse line

2 October 2017

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Angiogenesis: regulators and clinical applications

2 October 2017

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Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

2 October 2017

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Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4

2 October 2017

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Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature.

2 October 2017

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Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice

2 October 2017

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Defective heparan sulfate biosynthesis and neonatal lethality in mice lacking N-deacetylase/N-sulfotransferase-1

2 October 2017

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Abnormal mast cells in mice deficient in a heparin-synthesizing enzyme

2 October 2017

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Heparin is essential for the storage of specific granule proteases in mast cells

2 October 2017

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Structural features in heparin that interact with VEGF165 and modulate its biological activity

2 October 2017

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Dermatan sulfate released after injury is a potent promoter of fibroblast growth factor-2 function.

2 October 2017

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Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

2 October 2017

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Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

2 October 2017

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Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy.

2 October 2017

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

2 October 2017

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Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor

2 October 2017

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Extracellular matrix-resident growth factors and enzymes: possible involvement in tumor metastasis and angiogenesis

2 October 2017

1 reference

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Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate

2 October 2017

1 reference

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The role of angiogenesis in tumor growth

2 October 2017

1 reference

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Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior

2 October 2017

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Chinese hamster ovary cell mutants defective in glycosaminoglycan assembly and glucuronosyltransferase I.

2 July 2018

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Vascular endothelial growth factor as a marker of tumor endothelium.

2 July 2018

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Ultrastructural localization of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) to the abluminal plasma membrane and vesiculovacuolar organelles of tumor microvascular endothelium

2 July 2018

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Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development.

2 July 2018

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Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation.

23 September 2018

1 reference

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Endothelial heparan sulfate deficiency impairs L-selectin- and chemokine-mediated neutrophil trafficking during inflammatory responses

23 September 2018

1 reference

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The kinetics of FGF-2 binding to heparan sulfate proteoglycans and MAP kinase signaling

23 September 2018

1 reference

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Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups

23 September 2018

1 reference

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Loss of collagen XVIII enhances neovascularization and vascular permeability in atherosclerosis

23 September 2018

1 reference

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Inhibition by the soluble syndecan-1 ectodomains delays wound repair in mice overexpressing syndecan-1.

23 September 2018

1 reference

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Platelet-endothelial interaction in tumor angiogenesis and microcirculation

23 September 2018

1 reference

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Do morphogen gradients arise by diffusion?

23 September 2018

1 reference

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Role of syndecan-1 in leukocyte-endothelial interactions in the ocular vasculature

23 September 2018

1 reference

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Fibroblast growth factor-2 selectively stimulates angiogenesis of small vessels in arterial tree.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064806

Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development

23 September 2018

1 reference

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Heparan sulfate in trans potentiates VEGFR-mediated angiogenesis

23 September 2018

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12 December 2020

Isolation of endothelial cells from murine tissue

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12 December 2020

Syndecan-4 deficiency impairs the fetal vessels in the placental labyrinth

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12 December 2020

Heparanase as mediator of angiogenesis: mode of action

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12 December 2020

Nitrocellulose Filter Binding to Assess Binding of Glycosaminoglycans to Proteins

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12 December 2020

Undersulfated heparan sulfate in a Chinese hamster ovary cell mutant defective in heparan sulfate N-sulfotransferase

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12 December 2020

Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppression

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12 December 2020

Sensitive high-performance liquid chromatographic method with fluorometric detection for the determination of heparin and heparan sulfate in biological samples: application to human urinary heparan sulfate

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200610086

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

17470635

1 reference