Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia (Q36137651)

12 August 2017

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia (English)

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12 August 2017

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lymphoblastic leukemia

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1

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3 June 2020

Valeria Tosello

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3 June 2020

José M. Matés

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3 June 2020

Andrew L. Kung

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3 June 2020

Stephen Rayport

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3 June 2020

Carlos Cordon-Cardo

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3 June 2020

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Agnieszka A Wendorff

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Adolfo A Ferrando

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3 June 2020

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Jessica Sudderth

3

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3 June 2020

Marta Sánchez-Martín

4

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3 June 2020

Laura Belver

5

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3 June 2020

Luyao Xu

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3 June 2020

Mireia Castillo

9

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3 June 2020

J Erika Haydu

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3 June 2020

Javier Márquez

11

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3 June 2020

Ralph J DeBerardinis

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3 June 2020

Alberto Ambesi-Impiombato

2

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3 June 2020

language of work or name

English

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publication date

21 September 2015

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12 August 2017

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3 June 2020

volume

21

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3 June 2020

issue

10

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3 June 2020

page(s)

1182-1189

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Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing.

3 June 2020

cites work

1 reference

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An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598309

Notch signaling at a glance

2 October 2017

1 reference

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Autophagy in tumorigenesis and cancer therapy: Dr. Jekyll or Mr. Hyde?

2 October 2017

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Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

2 October 2017

1 reference

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Characterization of a pediatric T-cell acute lymphoblastic leukemia patient with simultaneous LYL1 and LMO2 rearrangements

2 October 2017

1 reference

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On becoming a T cell, a convergence of factors kick it up a Notch along the way.

2 October 2017

1 reference

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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

2 October 2017

1 reference

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Targeting metabolic transformation for cancer therapy.

2 October 2017

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Drug combination studies and their synergy quantification using the Chou-Talalay method

2 October 2017

1 reference

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Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.

2 October 2017

1 reference

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The molecular determinants of de novo nucleotide biosynthesis in cancer cells

2 October 2017

1 reference

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598309

Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598309

Launching the T-cell-lineage developmental programme

2 October 2017

1 reference

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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

2 October 2017

1 reference

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Novel mechanism of inhibition of rat kidney-type glutaminase by bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide (BPTES)

2 October 2017

1 reference

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Expression of functional human glutaminase in baculovirus system: affinity purification, kinetic and molecular characterization.

2 October 2017

1 reference

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NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598309

ATP citrate lyase inhibition can suppress tumor cell growth

2 October 2017

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

2 October 2017

1 reference

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Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

2 October 2017

1 reference

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ATP citrate lyase is an important component of cell growth and transformation

2 October 2017

1 reference

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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4598309

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

2 October 2017

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

2 October 2017

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Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation

2 October 2017

1 reference

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Akt stimulates aerobic glycolysis in cancer cells

2 October 2017

1 reference

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Pten dose dictates cancer progression in the prostate

2 October 2017

1 reference

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Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

2 October 2017

1 reference

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Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities

2 October 2017

1 reference

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The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation

23 September 2018

1 reference

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Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.3955

21 January 2018

Identifiers

DOI

10.1038/NM.3955

1 reference

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Dimensions Publication ID

3 June 2020

1031132896

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Fatcat ID

release_pca422govnghveeyjdogpsicka

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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3 June 2020

PubMed publication ID

26390244

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