EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression. (Q36169265)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26320100%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression (English)

1 reference

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23 February 2020

2

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23 February 2020

Matthew C Canver

3

1 reference

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23 February 2020

8

Bradley E Bernstein

1 reference

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23 February 2020

author name string

Aline Renneville

1

1 reference

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23 February 2020

Marie McConkey

4

1 reference

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23 February 2020

John M Krill-Burger

5

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23 February 2020

David M Dorfman

6

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23 February 2020

Edward B Holson

7

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23 February 2020

Stuart H Orkin

9

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23 February 2020

Daniel E Bauer

10

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23 February 2020

Benjamin L Ebert

11

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23 February 2020

language of work or name

English

0 references

publication date

28 August 2015

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23 February 2020

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23 February 2020

volume

126

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23 February 2020

issue

16

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23 February 2020

page(s)

1930-1939

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Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping

23 February 2020

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1 October 2017

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Lysine-specific demethylase 1 is a therapeutic target for fetal hemoglobin induction

1 October 2017

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1 October 2017

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Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A

1 October 2017

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Reawakening fetal hemoglobin: prospects for new therapies for the β-globin disorders

1 October 2017

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Proof of principle for transfusion of in vitro-generated red blood cells.

1 October 2017

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A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

1 October 2017

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H3K9 methyltransferase G9a and the related molecule GLP.

1 October 2017

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Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities

1 October 2017

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Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease

1 October 2017

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Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression

1 October 2017

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Dual role for the methyltransferase G9a in the maintenance of beta-globin gene transcription in adult erythroid cells

1 October 2017

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1 October 2017

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Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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1 October 2017

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Regulation of human fetal hemoglobin: new players, new complexities

1 October 2017

1 reference

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Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

1 October 2017

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Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains

1 October 2017

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Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3

1 October 2017

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Sustained induction of fetal hemoglobin by pulse butyrate therapy in sickle cell disease

1 October 2017

1 reference

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5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons

1 October 2017

1 reference

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Hemoglobin synthesis in murine virus-induced leukemic cells in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide

1 October 2017

1 reference

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G9a/GLP-dependent histone H3K9me2 patterning during human hematopoietic stem cell lineage commitment

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4608240

Pathogenesis and treatment of sickle cell disease

2 July 2018

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5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β+Thalassemia

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26320100

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2015-06-649087

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26320100%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26320100%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

26320100

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26320100%20AND%20SRC:MED&resulttype=core&format=json