Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research (Q36187959)

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English	Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research	scientific article

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

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João Pedro de Magalhães

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

João Pedro de Magalhães

1

object named as

João Pedro de Magalhães

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

language of work or name

1 reference

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publication date

1 January 2014

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

number of pages

3

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24 February 2020

13

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

17

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

2671-2673

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Low insulin-like growth factor-1 level predicts survival in humans with exceptional longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

LongevityMap: a database of human genetic variants associated with longevity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

How ageing processes influence cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Human Ageing Genomic Resources: integrated databases and tools for the biology and genetics of ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Whole transcriptome sequencing of the aging rat brain reveals dynamic RNA changes in the dark matter of the genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Aging, synaptic dysfunction, and insulin-like growth factor (IGF)-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Genetic signatures of exceptional longevity in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Rare and common variants: twenty arguments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Genome-environment interactions that modulate aging: powerful targets for drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

The GH/IGF1 axis and signaling pathways in the muscle and bone: mechanisms underlying age-related skeletal muscle wasting and osteoporosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Caloric restriction delays disease onset and mortality in rhesus monkeys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Design of aging intervention studies: the NIA interventions testing program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

FOXO3A genotype is strongly associated with human longevity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Functionally significant insulin-like growth factor I receptor mutations in centenarians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Does caloric restriction extend life in wild mice?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Genetic instability as the primary cause of human aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

1 October 2017

Dwarf mice and the ageing process.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

2 July 2018

Computational neuroanatomy of speech production.

1 reference

https://api.crossref.org/works/10.4161%2F15384101.2014.950151

21 January 2018

Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span

1 reference

https://api.crossref.org/works/10.4161%2F15384101.2014.950151

21 January 2018

Genes, culture, and aging flies--what the lab can and cannot tell us about natural genetic variation for senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614541

23 September 2018

Benchmarks for ageing studies

1 reference

https://api.crossref.org/works/10.4161%2F15384101.2014.950151

21 January 2018

Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/25486354

12 December 2020

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Identifiers

10.4161/15384101.2014.950151

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25486354%20AND%20SRC:MED&resulttype=core&format=json

24 February 2020

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