Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation (Q36267274)

13 August 2017

Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation (English)

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13 August 2017

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1

Stuart M. Pitson

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19 March 2024

5

Pu Xia

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19 March 2024

author name string

Paul A. B. Moretti

2

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19 March 2024

Julia R. Zebol

3

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19 March 2024

Helen E. Lynn

4

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19 March 2024

Mathew A. Vadas

6

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19 March 2024

Binks W. Wattenberg

7

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19 March 2024

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English

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publication date

1 October 2003

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PMC publication ID

213794

13 August 2017

15 October 2003

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National Center for Biotechnology Information

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full work available at URL

19 March 2024

http://emboj.embopress.org/content/22/20/5491.full.pdf

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https://europepmc.org/articles/PMC213794

19 March 2024

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https://europepmc.org/articles/PMC213794?pdf=render

19 March 2024

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https://doi.org/10.1093/emboj/cdg540

19 March 2024

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open access

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https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1093%2Femboj%2Fcdg540

19 March 2024

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https://onlinelibrary.wiley.com/doi/full/10.1093/emboj/cdg540

19 March 2024

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19 March 2024

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13 August 2017

22

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13 August 2017

20

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13 August 2017

5491-5500

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Signaling life and death in the thymus: timing is everything

13 August 2017

1 reference

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Activation loop phosphorylation and catalysis in protein kinases: is there functional evidence for the autoinhibitor model?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

The nucleotide-binding site of human sphingosine kinase 1

30 September 2017

1 reference

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Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

30 September 2017

1 reference

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IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation

30 September 2017

1 reference

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MAP kinase phosphatase as a locus of flexibility in a mitogen-activated protein kinase signaling network

30 September 2017

1 reference

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PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA)

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Cloning and characterization of a protein kinase A anchoring protein (AKAP)-related protein that interacts with and regulates sphingosine kinase 1 activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Sphingosine 1-phosphate signalling and termination at lipid phosphate receptors

30 September 2017

1 reference

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Sphingosine 1-phosphate, a key cell signaling molecule

30 September 2017

1 reference

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Pinning down proline-directed phosphorylation signaling

30 September 2017

1 reference

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Dichotomy of Ca2+ signals triggered by different phospholipid pathways in antigen stimulation of human mast cells

30 September 2017

1 reference

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Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-alpha signaling

30 September 2017

1 reference

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Lysophospholipids--receptor revelations

30 September 2017

1 reference

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EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration

30 September 2017

1 reference

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Endogenously produced urokinase-type plasminogen activator is a major determinant of the basal level of activated ERK/MAP kinase and prevents apoptosis in MDA-MB-231 breast cancer cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Sphingosine-1-phosphate phosphatases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Enzymes of sphingolipid metabolism: from modular to integrative signaling

30 September 2017

1 reference

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Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility

30 September 2017

1 reference

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NeW wrinkles for an old domain

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

An oncogenic role of sphingosine kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q22(1)

30 September 2017

1 reference

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Docking domains and substrate-specificity determination for MAP kinases

30 September 2017

1 reference

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Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes

30 September 2017

1 reference

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Calmodulin: a prototypical calcium sensor

30 September 2017

1 reference

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Sphingosine 1-phosphate signalling in mammalian cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=213794

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

30 September 2017

1 reference

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Cutting edge: extracellular signal-regulated kinase activates syk: a new potential feedback regulation of Fc epsilon receptor signaling.

30 September 2017

1 reference

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Signaling through scaffold, anchoring, and adaptor proteins

30 September 2017

1 reference

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A structural basis for substrate specificities of protein Ser/Thr kinases: primary sequence preference of casein kinases I and II, NIMA, phosphorylase kinase, calmodulin-dependent kinase II, CDK5, and Erk1.

30 September 2017

1 reference

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Ca2+/calmodulin-dependent translocation of sphingosine kinase: role in plasma membrane relocation but not activation.

30 September 2017

1 reference

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Molecular interpretation of ERK signal duration by immediate early gene products

29 June 2018

1 reference

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Expression of a catalytically inactive sphingosine kinase mutant blocks agonist-induced sphingosine kinase activation. A dominant-negative sphingosine kinase

29 June 2018

1 reference

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Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase

29 June 2018

1 reference

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Activation of sphingosine kinase in pheochromocytoma PC12 neuronal cells in response to trophic factors

29 June 2018

1 reference

12 December 2020

Grabbing phosphoproteins

1 reference

12 December 2020

Protein kinase C-dependent regulation of human erythroleukemia (HEL) cell sphingosine kinase activity

1 reference

12 December 2020

High density lipoproteins (HDL) interrupt the sphingosine kinase signaling pathway. A possible mechanism for protection against atherosclerosis by HDL

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDG540

1 reference

13 August 2017

1 reference

PMC publication ID

213794

13 August 2017

1 reference

PMC publication ID

213794