Dissecting MECP2 function in the central nervous system (Q36286552)

13 August 2017

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title

Dissecting MECP2 function in the central nervous system (English)

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13 August 2017

Noriyuki Kishi

1

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13 August 2017

Jeffrey D Macklis

series ordinal

2

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13 August 2017

publication date

1 September 2005

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Journal of Child Neurology

13 August 2017

published in

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13 August 2017

volume

20

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13 August 2017

issue

9

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13 August 2017

page(s)

753-759

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Neuropathology of Rett syndrome

13 August 2017

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Rett syndrome and MeCP2: linking epigenetics and neuronal function

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Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

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Purification, sequence, and cellular localization of a novel chromosomal protein that binds to methylated DNA

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MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

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Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice

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A mouse Mecp2-null mutation causes neurological symptoms that mimic Rett syndrome

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Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3

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Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome

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Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation

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Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions

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microRNAs: runts of the genome assert themselves

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A previously unidentified MECP2 open reading frame defines a new protein isoform relevant to Rett syndrome

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Expression of MeCP2 in postmitotic neurons rescues Rett syndrome in mice

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Mild overexpression of MeCP2 causes a progressive neurological disorder in mice.

21 January 2018

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Expression of the methyl-CpG-binding protein MeCP2 in rat brain. An ontogenetic study

21 January 2018

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Expression of MeCP2 in olfactory receptor neurons is developmentally regulated and occurs before synaptogenesis

21 January 2018

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Chromatin compaction by human MeCP2. Assembly of novel secondary chromatin structures in the absence of DNA methylation

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A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos

21 January 2018

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Notch signaling: cell fate control and signal integration in development

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Notch1 is essential for postimplantation development in mice.

21 January 2018

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Derepression of BDNF Transcription Involves Calcium-Dependent Phosphorylation of MeCP2

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Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndrome

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DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation

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21 January 2018

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21 January 2018

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Magnetic resonance imaging and clinical findings examined in adulthood-studies on three adults with Rett syndrome

21 January 2018

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Mutations of SCN1A, encoding a neuronal sodium channel, in two families with GEFS+2

21 January 2018

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21 January 2018

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Corepressor-dependent silencing of chromosomal regions encoding neuronal genes

21 January 2018

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Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice

21 January 2018

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10.1177/08830738050200091001

21 January 2018

Identifiers

DOI

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