Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases. (Q36288112)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9885250%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases (English)

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8 December 2019

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1

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8 December 2019

author name string

E J Robertson

series ordinal

2

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8 December 2019

language of work or name

English

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publication date

1 January 1999

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8 December 2019

number of pages

11

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inferred from page(s)

published in

Journal of Cell Biology

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8 December 2019

volume

144

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8 December 2019

issue

1

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8 December 2019

page(s)

139-149

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BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development

8 December 2019

cites work

1 reference

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30 September 2017

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Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity

30 September 2017

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Impaired fertility in mice deficient for the testicular germ-cell protease PC4

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Bioactivation of Müllerian inhibiting substance during gonadal development by a kex2/subtilisin-like endoprotease

30 September 2017

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The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

30 September 2017

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Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4.

30 September 2017

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SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.

30 September 2017

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Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP.

30 September 2017

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cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases

30 September 2017

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Lateral and axial signals involved in avian somite patterning: a role for BMP4

30 September 2017

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Generation of structural and functional diversity in furin-like proteins in Drosophila melanogaster by alternative splicing of the Dfur1 gene

30 September 2017

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Identification and functional expression of a new member of the mammalian Kex2-like processing endoprotease family: its striking structural similarity to PACE4

30 September 2017

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Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation

30 September 2017

1 reference

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Processing of a fusion protein by endoprotease in COS-1 cells for secretion of mature peptide by using a chimeric expression vector.

30 September 2017

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Processed Vg1 protein is an axial mesoderm inducer in Xenopus

30 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

PACE4: a subtilisin-like endoprotease prevalent in the anterior pituitary and regulated by thyroid status

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

A survey of furin substrate specificity using substrate phage display

30 September 2017

1 reference

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Processing of transforming growth factor beta 1 precursor by human furin convertase

30 September 2017

1 reference

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Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

30 September 2017

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Quality control in the secretory pathway

30 September 2017

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Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells

30 September 2017

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Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family

30 September 2017

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Novel regulators of bone formation: molecular clones and activities

30 September 2017

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Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide

30 September 2017

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Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin.

30 September 2017

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

30 September 2017

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Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone

30 September 2017

1 reference

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Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution

30 September 2017

1 reference

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Identification of a Second Human Subtilisin-Like Protease Gene in thefes/fpsRegion of Chromosome 15

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Biochemical characterization of the Drosophila dpp protein, a member of the transforming growth factor beta family of growth factors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

The new enzymology of precursor processing endoproteases

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Processing of mutated proinsulin with tetrabasic cleavage sites to mature insulin reflects the expression of furin in nonendocrine cell lines

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Control of cell pattern in the neural tube: regulation of cell differentiation by dorsalin-1, a novel TGF beta family member

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Conversion of a high molecular weight latent beta-TGF from chicken embryo fibroblasts into a low molecular weight active beta-TGF under acidic conditions

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Human transforming growth factor-beta 3: recombinant expression, purification, and biological activities in comparison with transforming growth factors-beta 1 and -beta 2.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Activin-binding protein from rat ovary is follistatin

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Bone-inducing activity of mature BMP-2b produced from a hybrid BMP-2a/2b precursor

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Influence of the carbohydrate moiety on the stability of glycoproteins

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Direct and long-range action of a DPP morphogen gradient.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Latent transforming growth factor-beta from human platelets. A high molecular weight complex containing precursor sequences.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2148113

Sequence requirements for precursor cleavage within the constitutive secretory pathway

22 September 2018

1 reference

12 December 2020

Localized synthesis of the Vg1 protein during early Xenopus development

1 reference

12 December 2020

Role of N-linked oligosaccharides attached to human renin expressed in COS cells

1 reference

12 December 2020

A simple procedure to increase efficiency of DEAE-dextran transfection of COS cells

1 reference

12 December 2020

Morphological differences in Xenopus embryonic mesodermal cells are specified as an early response to distinct threshold concentrations of activin

1 reference

12 December 2020

Cleavage of proalbumin peptides by furin reveals unexpected restrictions at the P2 and P'1 sites

1 reference

12 December 2020

Inhibition of activin receptor signaling promotes neuralization in Xenopus

1 reference

12 December 2020

Proprotein processing activity and cleavage site selectivity of the Kex2-like endoprotease PACE4

1 reference

12 December 2020

Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.144.1.139

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9885250%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9885250%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

9885250

1 reference