Site-specific O-glucosylation of the epidermal growth factor-like (EGF) repeats of notch: efficiency of glycosylation is affected by proper folding and amino acid sequence of individual EGF repeats (Q36298276)

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scientific article published on 7 August 2012

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English	Site-specific O-glucosylation of the epidermal growth factor-like (EGF) repeats of notch: efficiency of glycosylation is affected by proper folding and amino acid sequence of individual EGF repeats	scientific article published on 7 August 2012

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10 February 2020

Site-specific O-glucosylation of the epidermal growth factor-like (EGF) repeats of notch: efficiency of glycosylation is affected by proper folding and amino acid sequence of individual EGF repeats (English)

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10 February 2020

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10 February 2020

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Hideyuki Takeuchi

1

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10 February 2020

Joshua Kantharia

2

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10 February 2020

Maya K Sethi

3

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10 February 2020

Robert S Haltiwanger

5

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10 February 2020

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7 August 2012

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10 February 2020

Journal of Biological Chemistry

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10 February 2020

287

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10 February 2020

41

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10 February 2020

33934-33944

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10 February 2020

O-linked-N-acetylglucosamine modification of mammalian Notch receptors by an atypical O-GlcNAc transferase Eogt1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

Molecular cloning of a xylosyltransferase that transfers the second xylose to O-glucosylated epidermal growth factor repeats of notch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

Rumi functions as both a protein O-glucosyltransferase and a protein O-xylosyltransferase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

Fringe benefits: functional and structural impacts of O-glycosylation on the extracellular domain of Notch receptors

1 reference

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30 September 2017

Multiple O-glucosylation sites on Notch function as a buffer against temperature-dependent loss of signaling

1 reference

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30 September 2017

O-glucose trisaccharide is present at high but variable stoichiometry at multiple sites on mouse Notch1.

1 reference

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30 September 2017

Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi

1 reference

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30 September 2017

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation

1 reference

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30 September 2017

Role of glycosylation of Notch in development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

Identification of glycosyltransferase 8 family members as xylosyltransferases acting on O-glucosylated notch epidermal growth factor repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

Notch signaling: the core pathway and its posttranslational regulation

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30 September 2017

The canonical Notch signaling pathway: unfolding the activation mechanism

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30 September 2017

Role of unusual O-glycans in intercellular signaling

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30 September 2017

Roles of Pofut1 and O-fucose in mammalian Notch signaling

1 reference

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30 September 2017

Rumi is a CAP10 domain glycosyltransferase that modifies Notch and is required for Notch signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

Contributions of chaperone and glycosyltransferase activities of O-fucosyltransferase 1 to Notch signaling

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30 September 2017

Cloning, expression and characterization of a novel human CAP10-like gene hCLP46 from CD34(+) stem/progenitor cells

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30 September 2017

Chaperone activity of protein O-fucosyltransferase 1 promotes notch receptor folding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

O-fucosylation of notch occurs in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

WebLogo: A Sequence Logo Generator

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30 September 2017

Protein O -fucosyltransferase 1 is an essential component of Notch signaling pathways

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

Fringe modifies O-fucose on mouse Notch1 at epidermal growth factor-like repeats within the ligand-binding site and the Abruptex region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

O-glycosylation of EGF repeats: identification and initial characterization of a UDP-glucose: protein O-glucosyltransferase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

The N-terminal epidermal growth factor-like domain in factor IX and factor X represents an important recognition motif for binding to tissue factor

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30 September 2017

Modification of epidermal growth factor-like repeats with O-fucose. Molecular cloning and expression of a novel GDP-fucose protein O-fucosyltransferase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

Fringe is a glycosyltransferase that modifies Notch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3464504

30 September 2017

Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules

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30 September 2017

Purification and characterization of a GDP-fucose:polypeptide fucosyltransferase from Chinese hamster ovary cells

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30 September 2017

Haemophilia B: database of point mutations and short additions and deletions--fourth edition, 1993

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30 September 2017

O-linked fucose and other post-translational modifications unique to EGF modules

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30 September 2017

Structural and mechanistic insights into lunatic fringe from a kinetic analysis of enzyme mutants

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29 June 2018

Identification of twenty-one new mutations in the factor IX gene by SSCP analysis

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29 June 2018

O-linked-N-acetylglucosamine on extracellular protein domains mediates epithelial cell-matrix interactions.

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22 September 2018

Mammalian Notch is modified by D-Xyl-alpha1-3-D-Xyl-alpha1-3-D-Glc-beta1-O-Ser: implementation of a method to study O-glucosylation

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22 September 2018

O-linked N-acetylglucosamine is present on the extracellular domain of notch receptors

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22 September 2018

The O-fucosyltransferase O-fut1 is an extracellular component that is essential for the constitutive endocytic trafficking of Notch in Drosophila

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22 September 2018

Lunatic fringe, manic fringe, and radical fringe recognize similar specificity determinants in O-fucosylated epidermal growth factor-like repeats

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22 September 2018

Regulation of notch signaling by o-linked fucose.

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22 September 2018

Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

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Epidermal growth factor-like modules

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The structure of (xylose)2glucose-O-serine 53 found in the first epidermal growth factor-like domain of bovine blood clotting factor IX

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10.1074/JBC.M112.401315

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10 February 2020

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Europe PubMed Central

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10 February 2020

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10 February 2020

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