The natural polyamine spermine functions directly as a free radical scavenger. (Q36307719)

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4 December 2019

title

The natural polyamine spermine functions directly as a free radical scavenger (English)

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4 December 2019

5

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author name string

H C Ha

1

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4 December 2019

N S Sirisoma

2

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4 December 2019

P Kuppusamy

3

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J L Zweier

4

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4 December 2019

R A Casero

6

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4 December 2019

language of work or name

English

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publication date

1 September 1998

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Proceedings of the National Academy of Sciences of the United States of America

4 December 2019

published in

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volume

95

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issue

19

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4 December 2019

page(s)

11140-11145

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The role of polyamine catabolism in polyamine analogue-induced programmed cell death

4 December 2019

cites work

1 reference

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Antioxidative and metal-chelating effects of polyamines.

30 September 2017

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Antioxidant response element

30 September 2017

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Polyamines as targets for therapeutic intervention

30 September 2017

1 reference

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Identification of hypusine, an unusual amino acid, in a protein from human lymphocytes and of spermidine as its biosynthetic precursor

30 September 2017

1 reference

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30 September 2017

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Molecular mechanics of the interactions of spermine with DNA: DNA bending as a result of ligand binding

30 September 2017

1 reference

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Spermine and spermidine protection of plasmid DNA against single-strand breaks induced by singlet oxygen

30 September 2017

1 reference

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A proposed function for spermine and spermidine: protection of replicating DNA against damage by singlet oxygen

30 September 2017

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Involvement of the polyamine transport system in cellular uptake of the radioprotectants WR-1065 and WR-33278.

30 September 2017

1 reference

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Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines.

30 September 2017

1 reference

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Polyamine inhibition of lipoperoxidation. The influence of polyamines on iron oxidation in the presence of compounds mimicking phospholipid polar heads

30 September 2017

1 reference

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Detoxication of tyramine by the flavin-containing monooxygenase: stereoselective formation of the trans oxime

30 September 2017

1 reference

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Interactions of polyamines with ion channels

29 June 2018

1 reference

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DNA damage resulting from the oxidation of hydroquinone by copper: role for a Cu(II)/Cu(I) redox cycle and reactive oxygen generation.

29 June 2018

1 reference

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Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation

29 June 2018

1 reference

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Oxidized polyamines and the growth of human vascular endothelial cells. Prevention of cytotoxic effects by selective acetylation

29 June 2018

1 reference

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Site-specific oxidative DNA damage at polyguanosines produced by copper plus hydrogen peroxide.

29 June 2018

1 reference

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Polyamine depletion is associated with altered chromatin structure in HeLa cells

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21609

Effects of variation in the structure of spermine on the association with DNA and the induction of DNA conformational changes

29 June 2018

1 reference

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Antimalarial polyamine analogues

29 June 2018

1 reference

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When are metal ion-dependent hydroxyl and alkoxyl radical adducts of 5,5-dimethyl-1-pyrroline N-oxide artifacts?

22 September 2018

1 reference

12 December 2020

ESR evidence for the generation of reactive oxygen species from the copper-mediated oxidation of the benzene metabolite, hydroquinone: role in DNA damage

1 reference

12 December 2020

Use of 4-fluoro-L-ornithine to monitor metabolic flux through the polyamine biosynthetic pathway

1 reference

12 December 2020

N-oxygenation of primary amines and hydroxylamines and retroreduction of hydroxylamines by adult human liver microsomes and adult human flavin-containing monooxygenase 3

1 reference

12 December 2020

Polyamines differentially modulate the transcription of growth-associated genes in human colon carcinoma cells

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12 December 2020

On the subcellular localization of the polyamines

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12 December 2020

Spermine prevents endonuclease activation and apoptosis in thymocytes*1

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12 December 2020

Direct evidence for inhibition of free radical formation from Cu(I) and hydrogen peroxide by glutathione and other potential ligands using the EPR spin-trapping technique

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.95.19.11140

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4 December 2019

0 references

1 reference

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4 December 2019

PubMed publication ID

9736703

1 reference