Ubiquitylation of ion channels (Q36313080)

13 August 2017

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title

Ubiquitylation of ion channels (English)

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13 August 2017

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1

Hugues Abriel

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13 August 2017

Olivier Staub

2

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13 August 2017

publication date

1 December 2005

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13 August 2017

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13 August 2017

volume

20

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13 August 2017

page(s)

398-407

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Regulation of the cardiac voltage-gated Na+ channel (H1) by the ubiquitin-protein ligase Nedd4.

13 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Defective regulation of the epithelial Na+ channel by Nedd4 in Liddle's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Mechanism and function of deubiquitinating enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

ATP-sensitive potassium channelopathies: focus on insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Epithelial Na+ channel mutants causing Liddle's syndrome retain ability to respond to aldosterone and vasopressin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

21 January 2018

A protein's final ESCRT.

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

The mechanism underlying cystic fibrosis transmembrane conductance regulator transport from the endoplasmic reticulum to the proteasome includes Sec61beta and a cytosolic, deglycosylated intermediary

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Molecular bases for the recognition of tyrosine-based sorting signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

NEDD4L on human chromosome 18q21 has multiple forms of transcripts and is a homologue of the mouse Nedd4-2 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Regulation of nicotinic receptor expression by the ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na(+) channel cell surface expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Thapsigargin selectively rescues the trafficking defective LQT2 channels G601S and F805C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Nedd4 mediates control of an epithelial Na+ channel in salivary duct cells by cytosolic Na+

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Calcium-pump inhibitors induce functional surface expression of Delta F508-CFTR protein in cystic fibrosis epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Quality control in the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Role of the cytosolic chaperones Hsp70 and Hsp90 in maturation of the cardiac potassium channel HERG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Cell surface expression of the epithelial Na channel and a mutant causing Liddle syndrome: a quantitative approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Endocytic trafficking routes of wild type and DeltaF508 cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Cystic fibrosis transmembrane conductance regulator degradation depends on the lectins Htm1p/EDEM and the Cdc48 protein complex in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Inhibition of the epithelial Na+ channel by interaction of Nedd4 with a PY motif deleted in Liddle's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Protein regulation by monoubiquitin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

The Nedd4 family of E3 ubiquitin ligases: functional diversity within a common modular architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Multiple proteolytic systems, including the proteasome, contribute to CFTR processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Physiological functions of CLC Cl- channels gleaned from human genetic disease and mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Muscle metaboreflex control is diminished in normotensive obese women

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Solution structure of a Nedd4 WW domain-ENaC peptide complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Activity-dependent NMDA receptor degradation mediated by retrotranslocation and ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Molecular and cellular mechanisms of cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Mutations causing Liddle syndrome reduce sodium-dependent downregulation of the epithelial sodium channel in the Xenopus oocyte expression system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Epithelial sodium channel/degenerin family of ion channels: a variety of functions for a shared structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Brugada syndrome and fever: genetic and molecular characterization of patients carrying SCN5A mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Proteolysis of type I inositol 1,4,5-trisphosphate receptor in WB rat liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Altered ubiquitination and stability of aquaporin-1 in hypertonic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Epidermal growth factor regulates ubiquitination, internalization and proteasome-dependent degradation of connexin43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Ubiquitination and down-regulation of gap junction protein connexin-43 in response to 12-O-tetradecanoylphorbol 13-acetate treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Ubiquitylation of a melanosomal protein by HECT-E3 ligases serves as sorting signal for lysosomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

ROMK1 channel activity is regulated by monoubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

A common molecular basis for three inherited kidney stone diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Episodic ataxia type-1 mutations in the Kv1.1 potassium channel display distinct folding and intracellular trafficking properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

The Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

The C2 domain calcium-binding motif: structural and functional diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Mechanisms underlying ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Sumoylation silences the plasma membrane leak K+ channel K2P1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Assembly of functional CFTR chloride channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Ubiquitination and endocytosis of plasma membrane proteins: role of Nedd4/Rsp5p family of ubiquitin-protein ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

A mutation in the epithelial sodium channel causing Liddle disease increases channel activity in the Xenopus laevis oocyte expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

An internalization signal in ClC-5, an endosomal Cl-channel mutated in dent's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

A superfamily of protein tags: ubiquitin, SUMO and related modifiers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Relative contribution of Nedd4 and Nedd4-2 to ENaC regulation in epithelia determined by RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Proteasomal degradation of Kir6.2 channel protein and its inhibition by a Na+ channel blocker aprindine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Interaction of connexins with protein partners in the control of channel turnover and gating.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

A tyrosine-based sorting signal is involved in connexin43 stability and gap junction turnover.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

An epithelial serine protease activates the amiloride-sensitive sodium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Role of Sgk1 in salt and potassium homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Regulation of nicotinic acetylcholine receptor assembly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Degradation of CFTR by the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Inositol 1,4,5-trisphosphate receptor ubiquitination is mediated by mammalian Ubc7, a component of the endoplasmic reticulum-associated degradation pathway, and is inhibited by chelation of intracellular Zn2+

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Ubiquitination and proteasomal degradation of endogenous and exogenous inositol 1,4,5-trisphosphate receptors in alpha T3-1 anterior pituitary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

E3 ubiquitin ligase that recognizes sugar chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

A foldable CFTR{Delta}F508 biogenic intermediate accumulates upon inhibition of the Hsc70-CHIP E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Overview of the voltage-gated sodium channel family

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

M phase-specific expression and phosphorylation-dependent ubiquitination of the ClC-2 channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00033.2005

10.1152/PHYSIOL.00033.2005

21 January 2018

Identifiers

DOI

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13 August 2017

1 reference