Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly (Q36322209)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14757753%20AND%20SRC:MED&resulttype=core&format=json

18 November 2019

title

Clustering of Nck by a 12-residue Tir phosphopeptide is sufficient to trigger localized actin assembly (English)

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18 November 2019

2

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18 November 2019

author name string

Kenneth G Campellone

1

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18 November 2019

Tony Pawson

3

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18 November 2019

Marc W Kirschner

4

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18 November 2019

Donald J Tipper

5

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18 November 2019

John M Leong

6

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18 November 2019

language of work or name

English

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publication date

1 February 2004

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18 November 2019

number of pages

10

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inferred from page(s)

published in

Journal of Cell Biology

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18 November 2019

volume

164

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18 November 2019

issue

3

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18 November 2019

page(s)

407-416

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The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network

18 November 2019

cites work

1 reference

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Point mutants of EHEC intimin that diminish Tir recognition and actin pedestal formation highlight a putative Tir binding pocket

30 September 2017

1 reference

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Cellular control of actin nucleation

30 September 2017

1 reference

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Host focal adhesion protein domains that bind to the translocated intimin receptor (Tir) of enteropathogenic Escherichia coli (EPEC).

30 September 2017

1 reference

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The Nck family of adapter proteins: regulators of actin cytoskeleton

30 September 2017

1 reference

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N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

30 September 2017

1 reference

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Supermolecular structure of the enteropathogenic Escherichia coli type III secretion system and its direct interaction with the EspA-sheath-like structure

30 September 2017

1 reference

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Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cells

30 September 2017

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Enteropathogenic E. coli Tir binds Nck to initiate actin pedestal formation in host cells

30 September 2017

1 reference

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EspG, a novel type III system-secreted protein from enteropathogenic Escherichia coli with similarities to VirA of Shigella flexneri

30 September 2017

1 reference

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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

30 September 2017

1 reference

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Intimin and the host cell--is it bound to end in Tir(s)?

30 September 2017

1 reference

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Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier function

30 September 2017

1 reference

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Enteropathogenic Escherichia coli (EPEC) attachment to epithelial cells: exploiting the host cell cytoskeleton from the outside.

30 September 2017

1 reference

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Enteropathogenic Escherichia coli (EPEC) Tir receptor molecule does not undergo full modification when introduced into host cells by EPEC-independent mechanisms

30 September 2017

1 reference

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A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

30 September 2017

1 reference

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Identification of CesT, a chaperone for the type III secretion of Tir in enteropathogenic Escherichia coli.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

Enteropathogenic Escherichia coli translocated intimin receptor, Tir, requires a specific chaperone for stable secretion

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

The EspD protein of enterohemorrhagic Escherichia coli is required for the formation of bacterial surface appendages and is incorporated in the cytoplasmic membranes of target cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

30 September 2017

1 reference

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Expression of the EspB protein of enteropathogenic Escherichia coli within HeLa cells affects stress fibers and cellular morphology.

30 September 2017

1 reference

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A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells

30 September 2017

1 reference

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Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts

30 September 2017

1 reference

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Diarrheagenic Escherichia coli

30 September 2017

1 reference

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A pathogenic bacterium triggers epithelial signals to form a functional bacterial receptor that mediates actin pseudopod formation.

30 September 2017

1 reference

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Role of the eaeA gene in experimental enteropathogenic Escherichia coli infection

30 September 2017

1 reference

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The eaeB gene of enteropathogenic Escherichia coli is necessary for signal transduction in epithelial cells

30 September 2017

1 reference

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A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells

30 September 2017

1 reference

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Interaction of the enteropathogenic Escherichia coli protein, translocated intimin receptor (Tir), with focal adhesion proteins

30 September 2017

1 reference

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The Tir-binding region of enterohaemorrhagic Escherichia coli intimin is sufficient to trigger actin condensation after bacterial-induced host cell signalling

29 June 2018

1 reference

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Insertion of EspD into epithelial target cell membranes by infecting enteropathogenic Escherichia coli

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

The complete sequence of the locus of enterocyte effacement (LEE) from enteropathogenic Escherichia coli E2348/69.

29 June 2018

1 reference

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Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells

29 June 2018

1 reference

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A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12.

29 June 2018

1 reference

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EspH, a new cytoskeleton-modulating effector of enterohaemorrhagic and enteropathogenic Escherichia coli.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

The N-terminus of enteropathogenic Escherichia coli (EPEC) Tir mediates transport across bacterial and eukaryotic cell membranes.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

A tyrosine-phosphorylated 12-amino-acid sequence of enteropathogenic Escherichia coli Tir binds the host adaptor protein Nck and is required for Nck localization to actin pedestals

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

Targeting of an enteropathogenic Escherichia coli (EPEC) effector protein to host mitochondria.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

EspE, a novel secreted protein of attaching and effacing bacteria, is directly translocated into infected host cells, where it appears as a tyrosine-phosphorylated 90 kDa protein

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172230

Enteropathogenic and enterohaemorrhagic Escherichia coli : more subversive elements

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1083%2FJCB.200306032

Protein translocation into host epithelial cells by infecting enteropathogenic Escherichia coli

21 January 2018

1 reference

12 December 2020

Enteropathogenic E. coli translocated intimin receptor, Tir, interacts directly with alpha-actinin

1 reference

12 December 2020

Initial binding of Shiga toxin-producing Escherichia coli to host cells and subsequent induction of actin rearrangements depend on filamentous EspA-containing surface appendages

1 reference

12 December 2020

Phosphorylation of tyrosine 474 of the enteropathogenic Escherichia coli (EPEC) Tir receptor molecule is essential for actin nucleating activity and is preceded by additional host modifications

1 reference

12 December 2020

Characterization of translocation pores inserted into plasma membranes by type III-secreted Esp proteins of enteropathogenic Escherichia coli

1 reference

12 December 2020

Talin, a host cell protein, interacts directly with the translocated intimin receptor, Tir, of enteropathogenic Escherichia coli, and is essential for pedestal formation

1 reference

12 December 2020

The EspB protein of enterohaemorrhagic Escherichia coli interacts directly with alpha-catenin

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200306032

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14757753%20AND%20SRC:MED&resulttype=core&format=json

18 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14757753%20AND%20SRC:MED&resulttype=core&format=json

18 November 2019

PubMed publication ID

14757753

1 reference