CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. (Q36366075)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8551245%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

title

CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells (English)

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14 October 2019

1

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4

R A Flavell

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14 October 2019

5

C A Janeway

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14 October 2019

author name string

I Visintin

series ordinal

2

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14 October 2019

L Wen

series ordinal

3

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14 October 2019

language of work or name

English

0 references

publication date

1 January 1996

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Journal of Experimental Medicine

14 October 2019

published in

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14 October 2019

volume

183

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14 October 2019

issue

1

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14 October 2019

page(s)

67-76

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Constructing polycompetitor cDNAs for quantitative PCR.

14 October 2019

cites work

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Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients

30 September 2017

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30 September 2017

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Human T-cell clonal anergy is induced by antigen presentation in the absence of B7 costimulation

30 September 2017

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CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help.

30 September 2017

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T cell costimulation by B7/BB1 induces CD8 T cell-dependent tumor rejection: an important role of B7/BB1 in the induction, recruitment, and effector function of antitumor T cells.

30 September 2017

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Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells.

30 September 2017

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The structure of the mouse lymphocyte pore-forming protein perforin

30 September 2017

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CD28 activation pathway regulates the production of multiple T-cell-derived lymphokines/cytokines

30 September 2017

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Major histocompatibility complex-linked diabetogenic gene of the nonobese diabetic mouse. Analysis of genomic DNA amplified by the polymerase chain reaction

30 September 2017

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The CD28 ligand B7/BB1 provides costimulatory signal for alloactivation of CD4+ T cells

30 September 2017

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Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

30 September 2017

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Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7

30 September 2017

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The presumptive CDR3 regions of both T cell receptor alpha and beta chains determine T cell specificity for myoglobin peptides

30 September 2017

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B-cell surface antigen B7 provides a costimulatory signal that induces T cells to proliferate and secrete interleukin 2.

30 September 2017

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Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus

30 September 2017

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The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency

30 September 2017

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Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells.

30 September 2017

1 reference

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Beta-cell-cytotoxic CD8+ T cells from nonobese diabetic mice use highly homologous T cell receptor alpha-chain CDR3 sequences.

30 September 2017

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Presentation of beta-cell antigens to CD4+ and CD8+ T cells of non-obese diabetic mice

30 September 2017

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Evidence for the role of CD8+ cytotoxic T cells in the destruction of pancreatic beta-cells in nonobese diabetic mice.

28 June 2018

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Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone

28 June 2018

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Genetic analysis of autoimmune type 1 diabetes mellitus in mice

28 June 2018

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Organization, structure, and function of 95 kb of DNA spanning the murine T-cell receptor C alpha/C delta region.

28 June 2018

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B7 costimulates proliferation of CD4-8+ T lymphocytes but is not required for the deletion of immature CD4+8+ thymocytes

28 June 2018

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Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

28 June 2018

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Evidence for a preferential V beta usage by the T cells which adoptively transfer diabetes in NOD mice.

28 June 2018

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Organization of the V gene segments in mouse T-cell antigen receptor alpha/delta locus.

22 September 2018

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Islet-infiltrating lymphocytes from prediabetic NOD mice rapidly transfer diabetes to NOD-scid/scid mice

22 September 2018

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Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells

22 September 2018

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In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis

22 September 2018

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12 December 2020

Prevention of autoimmune insulitis by expression of I–E molecules in NOD mice

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12 December 2020

The natural history of lymphocyte subsets infiltrating the pancreas of NOD mice

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12 December 2020

An explanation for the protective effect of the MHC class II I–E molecule in murine diabetes

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12 December 2020

A cell culture model for T lymphocyte clonal anergy

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12 December 2020

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

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12 December 2020

Exclusive Expression of MHC Class II Proteins on CD45+ Cells in Pancreatic Islets of NOD Mice

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12 December 2020

Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice

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12 December 2020

Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes

1 reference

12 December 2020

Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant

1 reference

12 December 2020

Recurrent diabetes mellitus in the pancreas iso- and allograft. A light and electron microscopic and immunohistochemical analysis of four cases

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12 December 2020

Characterization of pancreatic islet cell infiltrates in NOD mice: effect of cell transfer and transgene expression

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12 December 2020

Adoptive transfer of diabetes into immunodeficient NOD-scid/scid mice. Relative contributions of CD4+ and CD8+ T-cells from diabetic versus prediabetic NOD.NON-Thy-1a donors

1 reference

12 December 2020

MHC-linked diabetogenic gene of the NOD mouse: molecular mapping of the 3' boundary of the diabetogenic region

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12 December 2020

Identifiers

DOI

10.1084/JEM.183.1.67

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8551245%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8551245%20AND%20SRC:MED&resulttype=core&format=json

14 October 2019

PubMed publication ID

8551245

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8551245%20AND%20SRC:MED&resulttype=core&format=json