Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin. (Q36385761)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23012363%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

title

Formation and structure of a NAIP5-NLRC4 inflammasome induced by direct interactions with conserved N- and C-terminal regions of flagellin (English)

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9 March 2020

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1

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9 March 2020

Christoph Diebolder

2

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9 March 2020

author name string

Marian Versteeg

3

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9 March 2020

Arie Schouten

4

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9 March 2020

T Harma C Brondijk

5

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9 March 2020

Eric G Huizinga

6

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9 March 2020

language of work or name

English

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publication date

25 September 2012

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Journal of Biological Chemistry

9 March 2020

published in

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9 March 2020

volume

287

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9 March 2020

issue

46

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9 March 2020

page(s)

38460-38472

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Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP.

9 March 2020

cites work

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The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

30 September 2017

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Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

30 September 2017

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30 September 2017

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Structure of the Drosophila Apoptosome at 6.9 Å Resolution

30 September 2017

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Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

30 September 2017

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Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

30 September 2017

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A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide

30 September 2017

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ATP binding by monarch-1/NLRP12 is critical for its inhibitory function

30 September 2017

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Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

30 September 2017

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An optimized protocol for protein purification in cultured mammalian cells using a tandem affinity purification approach

30 September 2017

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Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation

30 September 2017

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Inflammatory caspases and inflammasomes: master switches of inflammation

30 September 2017

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Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf

30 September 2017

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Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

30 September 2017

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CTF determination and correction in electron cryotomography.

30 September 2017

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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

30 September 2017

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Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

30 September 2017

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Nucleotide binding to CARD12 and its role in CARD12-mediated caspase-1 activation

30 September 2017

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Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells

30 September 2017

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Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses

30 September 2017

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Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy

30 September 2017

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Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice

30 September 2017

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

30 September 2017

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High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells

30 September 2017

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CLAN, a novel human CED-4-like gene

30 September 2017

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Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1

30 September 2017

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Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis

30 September 2017

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Structure of the bacterial flagellar protofilament and implications for a switch for supercoiling

30 September 2017

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30 September 2017

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30 September 2017

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WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

30 September 2017

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The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease

30 September 2017

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Method for the isolation of highly purified Salmonella flagellins

30 September 2017

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Three-dimensional structure of a double apoptosome formed by the Drosophila Apaf-1 related killer

30 September 2017

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Role of the disordered terminal regions of flagellin in filament formation and stability

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28 June 2018

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21 September 2018

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21 September 2018

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Identifiers

DOI

10.1074/JBC.M112.393512

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23012363%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23012363%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

PubMed publication ID

23012363

1 reference