Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities (Q36400215)

14 August 2017

Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities (English)

1 reference

14 August 2017

F Lühder

1

1 reference

14 August 2017

J Katz

series ordinal

2

1 reference

14 August 2017

C Benoist

series ordinal

3

1 reference

14 August 2017

D Mathis

series ordinal

4

1 reference

14 August 2017

language of work or name

English

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publication date

1 February 1998

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Journal of Experimental Medicine

14 August 2017

1 reference

14 August 2017

187

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14 August 2017

3

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14 August 2017

379-387

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Inactivation of T cell receptor peptide-specific CD4 regulatory T cells induces chronic experimental autoimmune encephalomyelitis (EAE).

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Genetics of insulin-dependent diabetes mellitus

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

T cell activation determined by T cell receptor number and tunable thresholds.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

High copy number I-Ab transgenes induce production of IgE through an interluekin 4-dependent mechanism.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Determinant capture as a possible mechanism of protection afforded by major histocompatibility complex class II molecules in autoimmune disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

A genome-wide search for human type 1 diabetes susceptibility genes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Insulin-dependent diabetes mellitus as an autoimmune disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Failure of a protective major histocompatibility complex class II molecule to delete autoreactive T cells in autoimmune diabetes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

The involvement of T cell receptor peptide-specific regulatory CD4+ T cells in recovery from antigen-induced autoimmune disease

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Genetic control of autoimmune diabetes in the NOD mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

A unified hypothesis for the complex genetics of HLA associations with IDDM.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Immune deficiency due to high copy numbers of an Ak beta transgene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Mice lacking MHC class II molecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

T cell receptor V gene usage of islet beta cell-reactive T cells is not restricted in non-obese diabetic mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

The effect of excess beta-chain synthesis on cell-surface expression of allele-mismatched class II heterodimers in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Tumor necrosis factor alpha in autoimmunity: pretty girl or old witch?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Prevention of autoimmune insulitis in nonobese diabetic mice by expression of major histocompatibility complex class I Ld molecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Murine CD8+ T cells that specifically delete autologous CD4+ T cells expressing V beta 8 TCR: a role of the Qa-1 molecule

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Complete characterization of the expressed immune response genes in Biozzi AB/H mice: structural and functional identity between AB/H and NOD A region molecules

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Thymic selection of CD8+ single positive cells with a class II major histocompatibility complex-restricted receptor

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Aspartate at position 57 of nonobese diabetic I-Ag7 beta-chain diminishes the spontaneous incidence of insulin-dependent diabetes mellitus.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Acceleration of diabetes in young NOD mice with a CD4+ islet-specific T cell clone

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

Complete prevention of diabetes in transgenic NOD mice expressing I-E molecules

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2212118

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

28 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Characterization of the insulin inhibition of the peptidolytic activities of the insulin-degrading enzyme-proteasome complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Another view of the selective model of thymocyte selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Exacerbated autoimmunity associated with a T helper-1 cytokine profile shift in H-2E-transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Prevention of autoimmune insulitis by expression of I–E molecules in NOD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Direct evidence for the contribution of the unique I-ANOD to the development of insulitis in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Prevention of diabetes in non-obese diabetic I-Ak transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

An explanation for the protective effect of the MHC class II I–E molecule in murine diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Correcting an immune-response deficiency by creating Eα gene transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Three recessive loci required for insulin-dependent diabetes in nonobese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Development of autoimmune insulitis is prevented in E alpha d but not in A beta k NOD transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

MHC-linked protection from diabetes dissociated from clonal deletion of T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Following a diabetogenic T cell from genesis through pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

The effect of bone marrow and thymus chimerism between non-obese diabetic (NOD) and NOD-E transgenic mice, on the expression and prevention of diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Genetic control of diabetes progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Functional sites on Ia molecules: a molecular dissection of A alpha immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

The expression of I-Ed molecules in F1 hybrid mice detected with antigen-specific, I-Ed-restricted cloned T-cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Human CD8+ T lymphocyte clones specific for T cell receptor V beta families expressed on autologous CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.187.3.379

The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders

21 January 2018

1 reference

12 December 2020

Quantitative thresholds of MHC class II I-E expressed on hemopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection

1 reference

12 December 2020

MHC control of the naive TCR alpha-chain repertoire

1 reference

12 December 2020

Differential expression of Ia glycoprotein complexes in F1 hybrid mice detected with alloreactive cloned T cell lines

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.187.3.379

1 reference

14 August 2017

1 reference

14 August 2017

PubMed publication ID

9449718

1 reference