The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes (Q36401296)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9815259%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

title

The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes (English)

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6 December 2019

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2

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6 December 2019

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R A Flavell

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6 December 2019

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R J Davis

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6 December 2019

1

M Rincón

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6 December 2019

author name string

D D Yang

3

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6 December 2019

L Weiss

4

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B Dérijard

5

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P Jayaraj

6

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6 December 2019

language of work or name

English

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publication date

1 November 1998

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Journal of Experimental Medicine

6 December 2019

published in

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6 December 2019

volume

188

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6 December 2019

issue

10

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6 December 2019

page(s)

1817-1830

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Interferon-gamma expression by Th1 effector T cells mediated by the p38 MAP kinase signaling pathway

6 December 2019

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30 September 2017

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Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH2-terminal kinase

30 September 2017

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Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

30 September 2017

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Cellular and biochemical requirements for thymocyte negative selection

30 September 2017

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Rac-1 dependent stimulation of the JNK/SAPK signaling pathway by Vav.

30 September 2017

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Positive and negative selection invoke distinct signaling pathways.

30 September 2017

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Selective interaction of JNK protein kinase isoforms with transcription factors

30 September 2017

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Activated Ras signals differentiation and expansion of CD4+8+ thymocytes

30 September 2017

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Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells

30 September 2017

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Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

30 September 2017

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Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis

30 September 2017

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Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

30 September 2017

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Negative selection of lymphocytes

30 September 2017

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JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

30 September 2017

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Peptides in positive and negative selection: a delicate balance

30 September 2017

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Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

30 September 2017

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AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.

21 January 2018

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Negative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists

30 September 2017

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Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

30 September 2017

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Involvement of p21ras distinguishes positive and negative selection in thymocytes

30 September 2017

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Development and selection of T cells: facts and puzzles

30 September 2017

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Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

30 September 2017

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An essential role for gp39, the ligand for CD40, in thymic selection.

30 September 2017

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Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine

30 September 2017

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T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection.

30 September 2017

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization

30 September 2017

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SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development

30 September 2017

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The influence of the MAPK pathway on T cell lineage commitment

28 June 2018

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Negative selection in the thymus includes semimature T cells

28 June 2018

1 reference

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Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes

28 June 2018

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A role for calcium influx in setting the threshold for CD4+CD8+ thymocyte negative selection.

28 June 2018

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Peripheral T cells undergoing superantigen-induced apoptosis in vivo express B220 and upregulate Fas and Fas ligand

28 June 2018

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Upregulation of surface markers on dying thymocytes

28 June 2018

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Transcription maps of polyoma virus-specific RNA: analysis by two-dimensional nuclease S1 gel mapping.

28 June 2018

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Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

28 June 2018

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Distinct sequence of negative or positive selection implied by thymocyte T-cell receptor densities

28 June 2018

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In vivo administration of monoclonal antibodies to the CD3 T cell receptor complex induces cell death (apoptosis) in immature thymocytes

28 June 2018

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B7 costimulates proliferation of CD4-8+ T lymphocytes but is not required for the deletion of immature CD4+8+ thymocytes

28 June 2018

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Reprogramming the signalling requirement for AP-1 (activator protein-1) activation during differentiation of precursor CD4+ T-cells into effector Th1 and Th2 cells

28 June 2018

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The MAP kinase pathway controls differentiation from double-negative to double-positive thymocyte

21 September 2018

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Intrathymic signals in thymocytes are mediated by p38 mitogen-activated protein kinase.

21 September 2018

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JNK is involved in signal integration during costimulation of T lymphocytes.

21 September 2018

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Intracellular signals that mediate thymic negative selection

21 September 2018

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Selective requirement for MAP kinase activation in thymocyte differentiation

21 September 2018

1 reference

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Two signals are required for negative selection of CD4+CD8+ thymocytes

21 September 2018

1 reference

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Proto-vav and gene expression.

21 September 2018

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Prostaglandin E2 and the increase of intracellular cAMP inhibit the expression of interleukin 2 receptors in human T cells

21 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.188.10.1817

Impaired Negative Selection of T Cells in Hodgkin's Disease Antigen CD30–Deficient Mice

21 January 2018

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https://api.crossref.org/works/10.1084%2FJEM.188.10.1817

CD28-B7 interactions are not required for intrathymic clonal deletion

21 January 2018

1 reference

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Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

21 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.188.10.1817

Raf regulates positive selection

21 January 2018

1 reference

12 December 2020

Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)

1 reference

12 December 2020

Positive selection of thymocytes

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12 December 2020

Fas modulation of apoptosis during negative selection of thymocytes

1 reference

12 December 2020

A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes

1 reference

12 December 2020

The effects of anti-CD3 antibodies on the development of T-cell receptor alpha beta + lymphocytes in embryonic thymus organ cultures

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12 December 2020

E2F-1 functions in mice to promote apoptosis and suppress proliferation

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12 December 2020

Identifiers

DOI

10.1084/JEM.188.10.1817

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9815259%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9815259%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

PubMed publication ID

9815259

1 reference