Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses (Q36446865)

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English	Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses (English)

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Europe PubMed Central

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14 August 2017

toll-like receptor

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Rachel R. Caspi

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Rachel R Caspi

6

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De Yang

1

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14 August 2017

Qian Chen

2

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14 August 2017

Shao Bo Su

3

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14 August 2017

Ping Zhang

4

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14 August 2017

Kahori Kurosaka

5

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14 August 2017

Suzanne M Michalek

7

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14 August 2017

Helene F Rosenberg

8

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14 August 2017

Ning Zhang

9

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14 August 2017

Joost J Oppenheim

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14 August 2017

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14 January 2008

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14 August 2017

Journal of Experimental Medicine

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14 August 2017

205

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Europe PubMed Central

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14 August 2017

1

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Europe PubMed Central

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14 August 2017

79-90

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Europe PubMed Central

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14 August 2017

Schistosoma mansoni infection in eosinophil lineage-ablated mice

1 reference

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Expanding the effector CD4 T-cell repertoire: the Th17 lineage.

1 reference

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Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.

1 reference

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Pathogen recognition and innate immunity

1 reference

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High mobility group box 1 protein interacts with multiple Toll-like receptors

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Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

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30 September 2017

Heat shock proteins as endogenous adjuvants in sterile and septic inflammation

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Alarmins: chemotactic activators of immune responses

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Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.

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Human ribonuclease A superfamily members, eosinophil-derived neurotoxin and pancreatic ribonuclease, induce dendritic cell maturation and activation

1 reference

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Toll-like receptor control of the adaptive immune responses

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Toll-like receptor signalling

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Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6

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Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases

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Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

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30 September 2017

Defensins: antimicrobial peptides of innate immunity

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30 September 2017

Eosinophil-derived neurotoxin (EDN), an antimicrobial protein with chemotactic activities for dendritic cells

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Heat shock proteins as ligands of toll-like receptors.

1 reference

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Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2.

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The immunobiology of schistosomiasis

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30 September 2017

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

1 reference

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Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP.

1 reference

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Receptor-mediated monitoring of tissue well-being via detection of soluble heparan sulfate by Toll-like receptor 4.

1 reference

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Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

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30 September 2017

Antimicrobial peptides of multicellular organisms

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30 September 2017

Oligosaccharides of Hyaluronan activate dendritic cells via toll-like receptor 4.

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30 September 2017

Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens.

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Fibrinogen stimulates macrophage chemokine secretion through toll-like receptor 4.

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Discrimination of bacterial lipoproteins by Toll-like receptor 6

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Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice

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A critical role for p38 mitogen-activated protein kinase in the maturation of human blood-derived dendritic cells induced by lipopolysaccharide, TNF-alpha, and contact sensitizers

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The extra domain A of fibronectin activates Toll-like receptor 4.

1 reference

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Eosinophil granule proteins and their role in disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234357

30 September 2017

LL-37, the neutrophil granule- and epithelial cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor to chemoattract human peripheral blood neutrophils, monocytes, and T cells

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Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

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The role of chemokines in the regulation of dendritic cell trafficking

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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Localization of eosinophil-derived neurotoxin and eosinophil cationic protein in neutrophilic leukocytes

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Dendritic cells and the control of immunity

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Purification of human eosinophil-derived neurotoxin

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Toll-like receptor 2 ligands inhibit TH2 responses to mite allergen.

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TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development.

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21 September 2018

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1 reference

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21 September 2018

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18195069

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The PI3 kinase, p38 SAP kinase, and NF-kappaB signal transduction pathways are involved in the survival and maturation of lipopolysaccharide-stimulated human monocyte-derived dendritic cells

1 reference

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1 reference

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Antimicrobial proteins act as "alarmins" in joint immune defense

1 reference

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Parasite-induced Th2 polarization is associated with down-regulated dendritic cell responsiveness to Th1 stimuli and a transient delay in T lymphocyte cycling

1 reference

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Major basic protein and eosinophil-derived neurotoxin concentrations in nasal-lavage fluid after antigen challenge: effect of systemic corticosteroids and relationship to eosinophil influx

1 reference

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Serum eosinophil cationic protein (ECP) and eosinophil protein X (EPX) in childhood asthma: the influence of atopy

1 reference

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Assessment of eosinophil granule proteins in various body fluids: is there a relation to clinical variables in childhood asthma?

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10.1084/JEM.20062027

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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