Redox regulation of Rac1 by thiol oxidation. (Q36451514)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25289457%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

title

Redox regulation of Rac1 by thiol oxidation (English)

1 reference

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20 February 2020

1

G. Aaron Hobbs

1 reference

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20 February 2020

6

Richard F Loeser

1 reference

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20 February 2020

author name string

Lauren E Mitchell

2

1 reference

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20 February 2020

Megan E Arrington

3

1 reference

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20 February 2020

Harsha P Gunawardena

4

1 reference

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20 February 2020

Molly J DeCristo

5

1 reference

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20 February 2020

Xian Chen

7

1 reference

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20 February 2020

Adrienne D Cox

8

1 reference

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20 February 2020

Sharon L Campbell

9

1 reference

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20 February 2020

publication date

5 October 2014

1 reference

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Free Radical Biology and Medicine

20 February 2020

published in

1 reference

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20 February 2020

volume

79

1 reference

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20 February 2020

page(s)

237-250

1 reference

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Rho GTPases, oxidation, and cell redox control

20 February 2020

cites work

1 reference

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Inhibition of Rac1 activity by controlled release of NSC23766 from chitosan microspheres effectively ameliorates osteoarthritis development in vivo

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Rac1 is required for matrix metalloproteinase 13 production by chondrocytes in response to fibronectin fragments

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Serine-71 phosphorylation of Rac1 modulates downstream signaling

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Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

30 September 2017

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Understanding the pK(a) of redox cysteines: the key role of hydrogen bonding.

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Redox regulation of Ras and Rho GTPases: mechanism and function

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Redox implications of AMPK-mediated signal transduction beyond energetic clues

30 September 2017

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A comprehensive survey of Ras mutations in cancer

30 September 2017

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Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

30 September 2017

1 reference

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Tyrosine phosphorylation of Rac1: a role in regulation of cell spreading

30 September 2017

1 reference

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Regulatory control or oxidative damage? Proteomic approaches to interrogate the role of cysteine oxidation status in biological processes.

30 September 2017

1 reference

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A palmitoylation switch mechanism regulates Rac1 function and membrane organization.

30 September 2017

1 reference

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Rac signaling in breast cancer: a tale of GEFs and GAPs.

30 September 2017

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Regulation of protein tyrosine phosphatases by reversible oxidation

30 September 2017

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Protein S-glutathiolation: redox-sensitive regulation of protein function.

30 September 2017

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The 'invisible hand': regulation of RHO GTPases by RHOGDIs

30 September 2017

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The diverse roles of Rac signaling in tumorigenesis

30 September 2017

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A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity

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Purification of Reversibly Oxidized Proteins (PROP) Reveals a Redox Switch Controlling p38 MAP Kinase Activity

30 September 2017

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SUMOylation of the GTPase Rac1 is required for optimal cell migration

30 September 2017

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30 September 2017

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Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif

30 September 2017

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Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation

30 September 2017

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Targeting and regulation of reactive oxygen species generation by Nox family NADPH oxidases

30 September 2017

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Role of peroxynitrite in the redox regulation of cell signal transduction pathways

30 September 2017

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Rac1 GTPase: a "Rac" of all trades.

30 September 2017

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Thiol chemistry and specificity in redox signaling

30 September 2017

1 reference

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Co-regulation of constitutive nitric oxide synthases and NADPH oxidase by the small GTPase Rac

30 September 2017

1 reference

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Regulation by reversible S-glutathionylation: molecular targets implicated in inflammatory diseases

30 September 2017

1 reference

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Rho GTPases in cancer cell biology

30 September 2017

1 reference

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RAC1 activity and intracellular ROS modulate the migratory potential of MCF-7 cells through a NADPH oxidase and NFkappaB-dependent mechanism

30 September 2017

1 reference

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Tumour maintenance is mediated by eNOS.

30 September 2017

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SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model

30 September 2017

1 reference

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Activated Rac1, but not the tumorigenic variant Rac1b, is ubiquitinated on Lys 147 through a JNK-regulated process

30 September 2017

1 reference

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The effects of superoxide dismutase on H2O2 formation

30 September 2017

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A novel analytical method for in vivo phosphate tracking

30 September 2017

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Requirement of Rac1 in the development of cardiac hypertrophy.

30 September 2017

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Free radical biology and medicine: it's a gas, man!

30 September 2017

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Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases

30 September 2017

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Real-time in vitro measurement of GTP hydrolysis

30 September 2017

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ALS2/Alsin regulates Rac-PAK signaling and neurite outgrowth

30 September 2017

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30 September 2017

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Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation

30 September 2017

1 reference

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Redox signaling: thiol chemistry defines which reactive oxygen and nitrogen species can act as second messengers

30 September 2017

1 reference

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The role of reactive oxygen species in homeostasis and degradation of cartilage

30 September 2017

1 reference

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Structural and biochemical studies of p21RasS-nitrosylation and nitric oxide-mediated guanine nucleotide exchange

30 September 2017

1 reference

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Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands

30 September 2017

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Akt protein kinase inhibits Rac1-GTP binding through phosphorylation at serine 71 of Rac1.

30 September 2017

1 reference

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The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

30 September 2017

1 reference

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

30 September 2017

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Direct, real-time measurement of rapid inorganic phosphate release using a novel fluorescent probe and its application to actomyosin subfragment 1 ATPase

30 September 2017

1 reference

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

30 September 2017

1 reference

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Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide

30 September 2017

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

30 September 2017

1 reference

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The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

30 September 2017

1 reference

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Post-translational modifications of p21rho proteins

30 September 2017

1 reference

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Intracellular localization of the P21rho proteins

30 September 2017

1 reference

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Increased Rac1b expression sustains colorectal tumor cell survival

30 September 2017

1 reference

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Rac1 cycling fast in melanoma with P29S.

28 June 2018

1 reference

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Focal-adhesion targeting links caveolin-1 to a Rac1-degradation pathway

21 September 2018

1 reference

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Nitrite reduction to nitric oxide in the vasculature

21 September 2018

1 reference

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Rac1 GTPase regulates cell genomic stability and senescence.

21 September 2018

1 reference

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Genetic deletion of Rac1 GTPase reveals its critical role in actin stress fiber formation and focal adhesion complex assembly.

21 September 2018

1 reference

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Mechanism of redox-mediated guanine nucleotide exchange on redox-active Rho GTPases

21 September 2018

1 reference

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Mechanism of free radical nitric oxide-mediated Ras guanine nucleotide dissociation

21 September 2018

1 reference

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S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide

21 September 2018

1 reference

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Backbone 1H, 13C, and 15N resonance assignments for the 21 kDa GTPase Rac1 complexed to GDP and Mg2+.

21 September 2018

1 reference

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Impairment of antimicrobial activity and nitric oxide production in alveolar macrophages from smokers of marijuana and cocaine

21 September 2018

1 reference

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Functional analysis of cdc42 residues required for Guanine nucleotide exchange

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4708892

Rac1 is required for the formation of three germ layers during gastrulation.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4708892

Ligand binding is the principal determinant of stability for the p21(H)-ras protein.

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4708892

Rac1 in the driver’s seat for melanoma

21 September 2018

1 reference

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Oxidation mimicking substitution of conservative cysteine in recoverin suppresses its membrane association

4 December 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/25289457

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25289457

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

S-glutathiolation of p21ras by peroxynitrite mediates endothelial insulin resistance caused by oxidized low-density lipoprotein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25289457

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.FREERADBIOMED.2014.09.027

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25289457%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25289457%20AND%20SRC:MED&resulttype=core&format=json

20 February 2020

PubMed publication ID

25289457

1 reference