Telomere length homeostasis (Q36495238)

14 August 2017

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title

Telomere length homeostasis (English)

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14 August 2017

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Joachim Lingner

2

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author name string

Nele Hug

series ordinal

1

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14 August 2017

publication date

2 June 2006

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14 August 2017

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14 August 2017

volume

115

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14 August 2017

issue

6

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14 August 2017

page(s)

413-425

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Specific DNA replication mutations affect telomere length in Saccharomyces cerevisiae

14 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00412-006-0067-3

Sir proteins, Rif proteins, and Cdc13p bind Saccharomyces telomeres in vivo

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00412-006-0067-3

Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00412-006-0067-3

Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00412-006-0067-3

Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo

21 January 2018

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12 December 2020

Inhibition of telomerase by G-quartet DNA structures

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12 December 2020

DNA sequences of telomeres maintained in yeast

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12 December 2020

RPA regulates telomerase action by providing Est1p access to chromosome ends

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12 December 2020

Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection

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12 December 2020

Yeast telomerase RNA: a flexible scaffold for protein subunits

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12 December 2020

Human POT1 facilitates telomere elongation by telomerase

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12 December 2020

The telomeric poly(ADP-ribose) polymerase, tankyrase 1, contains multiple binding sites for telomeric repeat binding factor 1 (TRF1) and a novel acceptor, 182-kDa tankyrase-binding protein (TAB182)

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12 December 2020

Origin of Concatemeric T7DNA

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12 December 2020

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression

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12 December 2020

TIN2, a new regulator of telomere length in human cells

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12 December 2020

PTOP interacts with POT1 and regulates its localization to telomeres

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12 December 2020

The involvement of the Mre11/Rad50/Nbs1 complex in the generation of G-overhangs at human telomeres

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12 December 2020

Telomere-end processing the terminal nucleotides of human chromosomes

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12 December 2020

Functional conservation of the telomerase protein Est1p in humans

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12 December 2020

Replication timing of DNA sequences associated with human centromeres and telomeres

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12 December 2020

Reverse transcriptase motifs in the catalytic subunit of telomerase

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12 December 2020

Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.

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12 December 2020

Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.

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12 December 2020

Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenance

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12 December 2020

Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends

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12 December 2020

Cell cycle-regulated trafficking of human telomerase to telomeres

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12 December 2020

A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation

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12 December 2020

The generation of proper constitutive G-tails on yeast telomeres is dependent on the MRX complex

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12 December 2020

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

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12 December 2020

Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13

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12 December 2020

All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3' terminus

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12 December 2020

Functional human telomeres are recognized as DNA damage in G2 of the cell cycle

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12 December 2020

POT1 and TRF2 cooperate to maintain telomeric integrity

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12 December 2020

Control of telomere length by the human telomeric protein TRF1

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12 December 2020

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

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12 December 2020

Late S phase-specific recruitment of Mre11 complex triggers hierarchical assembly of telomere replication proteins in Saccharomyces cerevisiae.

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12 December 2020

The yeast Pif1p helicase removes telomerase from telomeric DNA.

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12 December 2020

A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed

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12 December 2020

Est1 and Cdc13 as comediators of telomerase access

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12 December 2020

Delivery of yeast telomerase to a DNA break depends on the recruitment functions of Cdc13 and Est1

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12 December 2020

Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert.

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12 December 2020

Subtelomeric proteins negatively regulate telomere elongation in budding yeast

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12 December 2020

TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres

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12 December 2020

Human protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitro

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12 December 2020

Shelterin: the protein complex that shapes and safeguards human telomeres

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12 December 2020

Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure

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12 December 2020

Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states.

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12 December 2020

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

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12 December 2020

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

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12 December 2020

TIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complex

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12 December 2020

Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phase

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12 December 2020

Switching human telomerase on and off with hPOT1 protein in vitro

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12 December 2020

Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

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12 December 2020

Cell cycle-dependent regulation of yeast telomerase by Ku.

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12 December 2020

A phylogenetically based secondary structure for the yeast telomerase RNA.

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12 December 2020

Est1p as a cell cycle-regulated activator of telomere-bound telomerase

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12 December 2020

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

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12 December 2020

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

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12 December 2020

Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta.

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12 December 2020

Secondary structure of vertebrate telomerase RNA

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12 December 2020

Cdc13 both positively and negatively regulates telomere replication

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12 December 2020

Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro

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12 December 2020

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

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12 December 2020

Tankyrase-2 oligomerizes with tankyrase-1 and binds to both TRF1 (telomere-repeat-binding factor 1) and IRAP (insulin-responsive aminopeptidase)

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12 December 2020

Identification of human Rap1: implications for telomere evolution

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12 December 2020

Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia

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12 December 2020

TRF1 is degraded by ubiquitin-mediated proteolysis after release from telomeres

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12 December 2020

Pot1, the putative telomere end-binding protein in fission yeast and humans

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12 December 2020

Progressive cis-inhibition of telomerase upon telomere elongation.

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12 December 2020

A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2

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12 December 2020

Haploinsufficiency of mTR results in defects in telomere elongation

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12 December 2020

RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability

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12 December 2020

Rap1 affects the length and heterogeneity of human telomeres

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12 December 2020

Tankyrase promotes telomere elongation in human cells

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12 December 2020

A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.

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12 December 2020

Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.

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12 December 2020

A mutant with a defect in telomere elongation leads to senescence in yeast

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12 December 2020

Telomere length regulation in mice is linked to a novel chromosome locus.

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12 December 2020

A role for the Rb family of proteins in controlling telomere length

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12 December 2020

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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12 December 2020

Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres

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12 December 2020

Telomerase and DNA end replication: no longer a lagging strand problem?

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12 December 2020

Cdc13 delivers separate complexes to the telomere for end protection and replication

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12 December 2020

Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase

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12 December 2020

Lack of cell cycle regulation of telomerase activity in human cells

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12 December 2020

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12 December 2020

Circular chromosome formation in a fission yeast mutant defective in two ATM homologues

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12 December 2020

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

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12 December 2020

POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates

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12 December 2020

POT1 as a terminal transducer of TRF1 telomere length control

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12 December 2020

TRF1 is a dimer and bends telomeric DNA

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12 December 2020

Evidence suggesting that Pif1 helicase functions in DNA replication with the Dna2 helicase/nuclease and DNA polymerase delta

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12 December 2020

Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.

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12 December 2020

Telomere length homeostasis requires that telomerase levels are limiting

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12 December 2020

Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle

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12 December 2020

Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1

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12 December 2020

A protein-counting mechanism for telomere length regulation in yeast.

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12 December 2020

Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins

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12 December 2020

Generation of Telomeric G Strand Overhangs Involves Both G and C Strand Cleavage

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12 December 2020

Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation

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12 December 2020

Short telomeres, even in the presence of telomerase, limit tissue renewal capacity

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12 December 2020

Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2

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12 December 2020

Alterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha

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12 December 2020

Normal human telomeres are not late replicating

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12 December 2020

Cell cycle restriction of telomere elongation

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12 December 2020

Regulation of telomerase by telomeric proteins

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12 December 2020

Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length

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12 December 2020

Human telomeres have different overhang sizes at leading versus lagging strands

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12 December 2020

Control of human telomere length by TRF1 and TRF2

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12 December 2020

The human Rap1 protein complex and modulation of telomere length

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12 December 2020

TIN2 mediates functions of TRF2 at human telomeres

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12 December 2020

POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex

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12 December 2020

The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein

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12 December 2020

Cloning yeast telomeres on linear plasmid vectors

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12 December 2020

A telomerase component is defective in the human disease dyskeratosis congenita

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12 December 2020

Mammalian telomeres end in a large duplex loop

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12 December 2020

The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita

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12 December 2020

10.1007/S00412-006-0067-3

Identifiers

DOI

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14 August 2017

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