T cell expression of MyD88 is required for resistance to Toxoplasma gondii (Q36499083)

14 August 2017

T cell expression of MyD88 is required for resistance to Toxoplasma gondii (English)

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14 August 2017

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4

Adeeb H Rahman

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14 August 2017

David F LaRosa

1

1 reference

14 August 2017

Jason S Stumhofer

2

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14 August 2017

Andrew E Gelman

3

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14 August 2017

Devon K Taylor

5

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14 August 2017

Christopher A Hunter

6

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14 August 2017

Laurence A Turka

7

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14 August 2017

language of work or name

English

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publication date

28 February 2008

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Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

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14 August 2017

105

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14 August 2017

10

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14 August 2017

3855-3860

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

CpG DNA inhibits CD4+CD25+ Treg suppression through direct MyD88-dependent costimulation of effector CD4+ T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

The interleukin-1 receptor family

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Toll-like receptor 2 controls expansion and function of regulatory T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Fatal Mycobacterium tuberculosis infection despite adaptive immune response in the absence of MyD88.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Toll-like receptor control of the adaptive immune responses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Toll-like receptor signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Toll-like receptor ligands directly promote activated CD4+ T cell survival

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

TLR2 is expressed on activated T cells as a costimulatory receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Susceptibility of interleukin-2-deficient mice to Toxoplasma gondii is associated with a defect in the production of gamma interferon

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

The CD40/CD40 ligand interaction is required for resistance to toxoplasmic encephalitis.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-gamma- and tumor necrosis factor (TNF)-alpha-dependent host resistance to the intracellular pathogen, Toxoplasma gondii

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Toll-like receptors in cellular subsets of human tonsil T cells: altered expression during recurrent tonsillitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

MyD88-dependent but Toll-like receptor 2-independent innate immunity to Listeria: no role for either in macrophage listericidal activity

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Interferon-gamma: the major mediator of resistance against Toxoplasma gondii

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Importance of endogenous IFN-gamma for prevention of toxoplasmic encephalitis in mice.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268781

Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

Activation of TLR2 and TLR4 by glycosylphosphatidylinositols derived from Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

Both IL-12 and IL-18 contribute to small intestinal Th1-type immunopathology following oral infection with Toxoplasma gondii, but IL-12 is dominant over IL-18 in parasite control.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

Dissemination of Toxoplasma gondii to immunoprivileged organs and role of Toll/interleukin-1 receptor signalling for host resistance assessed by in vivo bioluminescence imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

Toll-dependent control mechanisms of CD4 T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

A critical role for IL-10 in limiting inflammation during toxoplasmic encephalitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

Human CD4+ T Cells Express TLR5 and Its Ligand Flagellin Enhances the Suppressive Capacity and Expression of FOXP3 in CD4+CD25+ T Regulatory Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

TLR2 engagement on CD8 T cells lowers the thresholdfor optimal antigen-induced T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0706663105

Critical roles of myeloid differentiation factor 88-dependent proinflammatory cytokine release in early phase clearance of Listeria monocytogenes in mice

21 January 2018

1 reference

12 December 2020

Genetically Resistant Mice Lacking MyD88-Adapter Protein Display a High Susceptibility to Leishmania major Infection Associated with a Polarized Th2 Response

1 reference

12 December 2020

In the absence of endogenous IFN-gamma, mice develop unimpaired IL-12 responses to Toxoplasma gondii while failing to control acute infection

1 reference

12 December 2020

Augmentation of naive, Th1 and Th2 effector CD4 responses by IL-6, IL-1 and TNF

1 reference

12 December 2020

MyD88-mediated stabilization of interferon-gamma-induced cytokine and chemokine mRNA

1 reference

12 December 2020

TLR9 is required for the gut-associated lymphoid tissue response following oral infection of Toxoplasma gondii

1 reference

12 December 2020

Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation

1 reference

12 December 2020

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

1 reference

12 December 2020

Cutting edge: TLR2 directly triggers Th1 effector functions

1 reference

12 December 2020

Cutting edge: IL-12 is required for the maintenance of IFN-gamma production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0706663105

1 reference

14 August 2017

0 references

1 reference

14 August 2017

PubMed publication ID

18308927

1 reference