The genetics of human longevity (Q36520988)

14 August 2017

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title

The genetics of human longevity (English)

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14 August 2017

1

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14 August 2017

Daniela Monti

6

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Graham Pawelec

object named as

Graham Pawelec

7

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Claudio Franceschi

10

object named as

Claudio Franceschi

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14 August 2017

9

Efstathios S Gonos

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14 August 2017

Stefano Salvioli

2

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14 August 2017

Federica Sevini

3

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14 August 2017

Silvana Valensin

4

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14 August 2017

Laura Celani

5

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14 August 2017

Giovanna De Benedictis

8

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14 August 2017

language of work or name

English

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publication date

1 May 2006

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Annals of the New York Academy of Sciences

14 August 2017

published in

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14 August 2017

volume

1067

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14 August 2017

page(s)

252-263

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Network biology: understanding the cell's functional organization

14 August 2017

cites work

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https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Quantifying the relevance of different mediators in the human immune cell network

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Serum IL-1beta levels in health and disease: a population-based study. 'The InCHIANTI study'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Predicting death from tumour necrosis factor-alpha and interleukin-6 in 80-year-old people

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Elevated levels of tumor necrosis factor alpha and mortality in centenarians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

The -174 C/G locus affects in vitro/in vivo IL-6 production during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Gender-specific association between -1082 IL-10 promoter polymorphism and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Interleukin-10 promoter polymorphism in sporadic Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Centenarians as a model for healthy aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Gene/longevity association studies at four autosomal loci (REN, THO, PARP, SOD2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

The challenge of secondary prevention for coronary heart disease in older patients: findings from the British Women's Heart and Health Study and the British Regional Heart Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Insulin-like growth factors and neoplasia.

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Adipokines: molecular links between obesity and atheroslcerosis

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Role of interaction between variants in the PPARG and interleukin-6 genes on obesity related metabolic risk factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Low insulin resistance and preserved beta-cell function contribute to human longevity but are not associated with TH-INS genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

p53 variants predisposing to cancer are present in healthy centenarians

21 January 2018

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https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Variation in the human TP53 gene affects old age survival and cancer mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

The different apoptotic potential of the p53 codon 72 alleles increases with age and modulates in vivo ischaemia-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

A study of the average effect of the 3'APOB-VNTR polymorphism on lipidemic parameters could explain why the short alleles (<35 repeats) are rare in centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Replication studies in longevity: puzzling findings in Danish centenarians at the 3'APOB-VNTR locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Unique lipoprotein phenotype and genotype associated with exceptional longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

p66(shc) is highly expressed in fibroblasts from centenarians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Chemokines, sTNF-Rs and sCD30 serum levels in healthy aged people and centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

The interleukin-6 −174 G>C promoter polymorphism is associated with a higher risk of death after an acute coronary syndrome in male elderly patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1196%2FANNALS.1354.033

21 January 2018

Identifiers

DOI

10.1196/ANNALS.1354.033

1 reference

14 August 2017

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