Mitochondria and cancer: Warburg addressed (Q36547748)

14 August 2017

1 reference

title

Mitochondria and cancer: Warburg addressed (English)

1 reference

14 August 2017

D C Wallace

1

1 reference

14 August 2017

publication date

1 January 2005

1 reference

Cold Spring Harbor Symposia on Quantitative Biology

14 August 2017

published in

1 reference

14 August 2017

volume

70

1 reference

14 August 2017

page(s)

363-374

1 reference

Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma

14 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

The akt kinase: molecular determinants of oncogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

On the InterAktion between hexokinase and the mitochondrion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Advances in protein kinase B signalling: AKTion on multiple fronts

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Separation of cytochrome c-dependent caspase activation from thiol-disulfide redox change in cells lacking mitochondrial DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mitochondrial DNA and human evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mitochondrial DNA alterations in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Why do cancers have high aerobic glycolysis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mitochondrial proteome: altered cytochrome c oxidase subunit levels in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Radiation of human mitochondria DNA types analyzed by restriction endonuclease cleavage patterns

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

A common mitochondrial DNA variant associated with susceptibility to dilated cardiomyopathy in two different populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mitochondrial proteome: cancer-altered metabolism associated with cytochrome c oxidase subunit level variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Glucose metabolism in cancer: importance of transcription factor-DNA interactions within a short segment of the proximal region og the type II hexokinase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Aberrant glycolytic metabolism of cancer cells: a remarkable coordination of genetic, transcriptional, post-translational, and mutational events that lead to a critical role for type II hexokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

The structure of human mitochondrial DNA variation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Natural selection shaped regional mtDNA variation in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

mtDNA mutations increase tumorigenicity in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Somatic mutations of the mitochondrial genome in human colorectal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

A common mitochondrial DNA variant is associated with insulin resistance in adult life.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Effects of purifying and adaptive selection on regional variation in human mtDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Extension of murine life span by overexpression of catalase targeted to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

AKT plays a central role in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Premature ageing in mice expressing defective mitochondrial DNA polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Cytoplasmic transfer of the mtDNA nt 8993 T-->G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mitochondrial DNA variation in human evolution and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mutations in the promoter reveal a cause for the reduced expression of the human manganese superoxide dismutase gene in cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Mitochondrial adenine nucleotide translocase is modified oxidatively during aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Electron Transfer between Cytochrome c and p66Shc Generates Reactive Oxygen Species that Trigger Mitochondrial Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2005.70.035

21 January 2018

Identifiers

DOI

10.1101/SQB.2005.70.035

1 reference

14 August 2017

1 reference