Non-conducting functions of voltage-gated ion channels (Q36599917)

15 August 2017

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title

Non-conducting functions of voltage-gated ion channels (English)

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15 August 2017

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Leonard K Kaczmarek

1

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15 August 2017

language of work or name

English

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publication date

1 October 2006

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Nature Reviews Neuroscience

15 August 2017

published in

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15 August 2017

volume

7

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15 August 2017

issue

10

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15 August 2017

page(s)

761-771

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The TRP ion channel family.

15 August 2017

cites work

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Apoptosis recruits two-pore domain potassium channels used for homeostatic volume regulation

21 January 2018

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Biosynthesis and characterization of the brain-specific membrane protein DPPX, a dipeptidyl peptidase IV-related protein

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Signaling protein complexes associated with neuronal ion channels

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Voltage-gated potassium channels in cell proliferation

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Oncogenic potential of EAG K(+) channels

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Role of voltage-gated potassium channels in cancer.

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Ether a go-go potassium channels as human cervical cancer markers

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Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene

31 March 2020

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Shaker-type potassium channel subunits differentially control oligodendrocyte progenitor proliferation

31 March 2020

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Modulation of Kv1.5 currents by Src tyrosine phosphorylation: potential role in the differentiation of astrocytes

31 March 2020

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Changes in ion channel expression accompany cell cycle progression of spinal cord astrocytes

31 March 2020

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Expression of voltage-gated potassium channels Kv1.3 and Kv1.5 in human gliomas

31 March 2020

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Calcium/calmodulin-dependent protein kinase II phosphorylates and regulates the Drosophila eag potassium channel

31 March 2020

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The eag potassium channel binds and locally activates calcium/calmodulin-dependent protein kinase II.

31 March 2020

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Differential localization of rat Eag1 and Eag2 K+ channels in hippocampal neurons.

31 March 2020

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Genetic dissection of functional contributions of specific potassium channel subunits in habituation of an escape circuit in Drosophila.

31 March 2020

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Calcium/calmodulin-dependent protein kinase II and potassium channel subunit eag similarly affect plasticity in Drosophila.

31 March 2020

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Expression of ether à go-go potassium channels in human gliomas.

31 March 2020

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A voltage-driven switch for ion-independent signaling by ether-à-go-go K+ channels

31 March 2020

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Regulation of calcium/calmodulin-dependent protein kinase II activation by intramolecular and intermolecular interactions.

31 March 2020

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Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain

31 March 2020

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Cloning and expression of cDNA and genomic clones encoding three delayed rectifier potassium channels in rat brain

31 March 2020

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Immunohistochemical localization of five members of the Kv1 channel subunits: contrasting subcellular locations and neuron-specific co-localizations in rat brain

31 March 2020

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State-dependent inactivation of the Kv3 potassium channel

31 March 2020

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K+ channels as targets for specific immunomodulation

31 March 2020

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Expression of voltage-gated potassium channels decreases cellular protein tyrosine phosphorylation

31 March 2020

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Kv1.3 channel gene-targeted deletion produces "Super-Smeller Mice" with altered glomeruli, interacting scaffolding proteins, and biophysics.

31 March 2020

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Deletion of the K(V)1.1 potassium channel causes epilepsy in mice

31 March 2020

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Pleiotropic effects of a disrupted K+ channel gene: reduced body weight, impaired motor skill and muscle contraction, but no seizures

31 March 2020

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Molecular proximity of Kv1.3 voltage-gated potassium channels and beta(1)-integrins on the plasma membrane of melanoma cells: effects of cell adherence and channel blockers

31 March 2020

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Activity-independent homeostasis in rhythmically active neurons

31 March 2020

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Modulation of A-type potassium channels by a family of calcium sensors

31 March 2020

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Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4

31 March 2020

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Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like properties

31 March 2020

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Activity-Independent Coregulation of IA and Ih in Rhythmically Active Neurons

31 March 2020

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Overexpression of a hyperpolarization-activated cation current (Ih) channel gene modifies the firing activity of identified motor neurons in a small neural network

31 March 2020

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MPS-1 is a K+ channel beta-subunit and a serine/threonine kinase

31 March 2020

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A superfamily of small potassium channel subunits: form and function of the MinK-related peptides (MiRPs).

31 March 2020

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The slowpoke channel binding protein Slob from Drosophila melanogaster exhibits regulatable protein kinase activity

31 March 2020

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Regulation of ion channel expression by cytoplasmic subunits

31 March 2020

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Functional and molecular aspects of voltage-gated K+ channel beta subunits

31 March 2020

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Modulation of voltage-dependent Shaker family potassium channels by an aldo-keto reductase.

31 March 2020

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KChIPs and Kv4 alpha subunits as integral components of A-type potassium channels in mammalian brain

31 March 2020

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Calsenilin: a calcium-binding protein that interacts with the presenilins and regulates the levels of a presenilin fragment

31 March 2020

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DREAM is a Ca2+-regulated transcriptional repressor

31 March 2020

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A role for calsenilin and related proteins in multiple aspects of neuronal function

31 March 2020

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Transcriptional repressor DREAM regulates T-lymphocyte proliferation and cytokine gene expression.

31 March 2020

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Activity-dependent regulation of voltage-gated Na+ channel expression in Mat-LyLu rat prostate cancer cell line

31 March 2020

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Neuronal characteristics of small-cell lung cancer

31 March 2020

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Small-cell lung cancer (human): potentiation of endocytic membrane activity by voltage-gated Na(+) channel expression in vitro

31 March 2020

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A potential novel marker for human prostate cancer: voltage-gated sodium channel expression in vivo.

31 March 2020

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Voltage-gated sodium channel expression and potentiation of human breast cancer metastasis.

31 March 2020

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T-lymphocyte invasiveness: control by voltage-gated Na+ channel activity.

31 March 2020

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Serum concentration modifies amplitude and kinetics of voltage-gated Na+ current in the Mat-LyLu cell line of rat prostate cancer

31 March 2020

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Heterophilic interactions of sodium channel beta1 subunits with axonal and glial cell adhesion molecules

31 March 2020

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Sodium channel beta subunits mediate homophilic cell adhesion and recruit ankyrin to points of cell-cell contact

31 March 2020

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Sodium channel beta1 and beta3 subunits associate with neurofascin through their extracellular immunoglobulin-like domain

31 March 2020

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Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes

31 March 2020

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Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R

31 March 2020

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Tenascin-R is a functional modulator of sodium channel beta subunits

31 March 2020

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Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin

31 March 2020

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A common ankyrin-G-based mechanism retains KCNQ and NaV channels at electrically active domains of the axon

31 March 2020

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Structural requirements for interaction of sodium channel beta 1 subunits with ankyrin

31 March 2020

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A sodium channel signaling complex: modulation by associated receptor protein tyrosine phosphatase beta

31 March 2020

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Sodium channel beta1 subunits promote neurite outgrowth in cerebellar granule neurons

31 March 2020

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beta Subunits of voltage-gated sodium channels are novel substrates of beta-site amyloid precursor protein-cleaving enzyme (BACE1) and gamma-secretase

31 March 2020

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Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration

31 March 2020

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Voltage sensor of excitation-contraction coupling in skeletal muscle

31 March 2020

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Evidence for conformational coupling between two calcium channels

31 March 2020

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Structure and regulation of voltage-gated Ca2+ channels

31 March 2020

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Alternative splicing of the voltage-gated Ca2+ channel beta4 subunit creates a uniquely folded N-terminal protein binding domain with cell-specific expression in the cerebellar cortex

31 March 2020

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Evidence for a voltage-dependent enhancement of neurotransmitter release mediated via the synaptic protein interaction site of N-type Ca2+ channels

31 March 2020

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Calcium- and dynamin-independent endocytosis in dorsal root ganglion neurons

31 March 2020

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Ca(2+)-independent but voltage-dependent secretion in mammalian dorsal root ganglion neurons

31 March 2020

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Generation, control, and processing of cellular calcium signals

31 March 2020

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Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway

31 March 2020

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Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons

31 March 2020

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Calcium regulation of neuronal gene expression

31 March 2020

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Molecular basis of calmodulin tethering and Ca2+-dependent inactivation of L-type Ca2+ channels

31 March 2020

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TRP ion channels in the nervous system.

31 March 2020

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Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7.

31 March 2020

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TRPV6 and prostate cancer: cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression

31 March 2020

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The transient receptor potential superfamily of ion channels

31 March 2020

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Dual-function ion channel/protein kinases: novel components of vertebrate magnesium regulatory mechanisms.

31 March 2020

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ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

31 March 2020

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Immunocyte Ca2+ influx system mediated by LTRPC2.

31 March 2020

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TRPM2 is an ion channel that modulates hematopoietic cell death through activation of caspases and PARP cleavage.

31 March 2020

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TRP-PLIK, a bifunctional protein with kinase and ion channel activities

31 March 2020

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Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene family

31 March 2020

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Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia

31 March 2020

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Characterization of the Protein Kinase Activity of TRPM7/ChaK1, a Protein Kinase Fused to the Transient Receptor Potential Ion Channel

31 March 2020

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Receptor-mediated regulation of the TRPM7 channel through its endogenous protein kinase domain

31 March 2020

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The channel kinases TRPM6 and TRPM7 are functionally nonredundant

31 March 2020

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The Caenorhabditis elegans autosomal dominant polycystic kidney disease gene homologs lov-1 and pkd-2 act in the same pathway

31 March 2020

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The N-terminal extracellular domain is required for polycystin-1-dependent channel activity

31 March 2020

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Polycystin-2 regulates proliferation and branching morphogenesis in kidney epithelial cells

31 March 2020

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A family of hyperpolarization-activated mammalian cation channels

31 March 2020

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Differential distribution of four hyperpolarization-activated cation channels in mouse brain

31 March 2020

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Cloning and localization of the hyperpolarization-activated cyclic nucleotide-gated channel family in rat brain

31 March 2020

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Calcium influx through HCN channels does not contribute to cAMP-enhanced transmission.

31 March 2020

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Roles of Ca2+, hyperpolarization and cyclic nucleotide-activated channel activation, and actin in temporal synaptic tagging.

31 March 2020

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Temporal synaptic tagging by I(h) activation and actin: involvement in long-term facilitation and cAMP-induced synaptic enhancement.

31 March 2020

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Enhancement of synaptic transmission by cyclic AMP modulation of presynaptic Ih channels

31 March 2020

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Sites of proteolytic processing and noncovalent association of the distal C-terminal domain of CaV1.1 channels in skeletal muscle

31 March 2020

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N-methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons

31 March 2020

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Signal transduction. RIPping tyrosine kinase receptors apart

31 March 2020

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Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus

31 March 2020

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Regulation of adenylyl cyclase from Paramecium by an intrinsic potassium conductance

31 March 2020

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Ionic Mechanisms of Excitation in Paramecium

31 March 2020

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Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor

31 March 2020

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A voltage sensor-domain protein is a voltage-gated proton channel

31 March 2020

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A voltage-gated proton-selective channel lacking the pore domain

31 March 2020

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Mediation of neuronal apoptosis by enhancement of outward potassium current.

31 March 2020

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NMDA receptor-mediated K+ efflux and neuronal apoptosis

31 March 2020

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Potassium is a critical regulator of apoptotic enzymes in vitro and in vivo.

31 March 2020

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Mediation of neuronal apoptosis by Kv2.1-encoded potassium channels.

31 March 2020

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Mitochondrial factors with dual roles in death and survival

31 March 2020

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Kv2.1: a voltage-gated k+ channel critical to dynamic control of neuronal excitability.

31 March 2020

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Stimulation of Kv1.3 potassium channels by death receptors during apoptosis in Jurkat T lymphocytes

31 March 2020

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31 March 2020

From molecule to malady

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Mutations in voltage-gated potassium channel KCNC3 cause degenerative and developmental central nervous system phenotypes

31 March 2020

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Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B.

31 March 2020

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Functional and biochemical analysis of a sodium channel beta1 subunit mutation responsible for generalized epilepsy with febrile seizures plus type 1

31 March 2020

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Sodium channel beta4 subunit: down-regulation and possible involvement in neuritic degeneration in Huntington's disease transgenic mice

31 March 2020

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Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?

31 March 2020

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Nuclear localization and dominant-negative suppression by a mutant SKCa3 N-terminal channel fragment identified in a patient with schizophrenia.

31 March 2020

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Differential expression of two distinct forms of mRNA encoding members of a dipeptidyl aminopeptidase family

31 March 2020

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31 March 2020

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Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases

31 March 2020

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DPP10 modulates Kv4-mediated A-type potassium channels

31 March 2020

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Microglia Kv1.3 channels contribute to their ability to kill neurons.

31 March 2020

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TRPV6 potentiates calcium-dependent cell proliferation

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRN1988

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15 August 2017

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