Drosophila germ-line modulation of insulin signaling and lifespan (Q36609160)

15 August 2017

Drosophila germ-line modulation of insulin signaling and lifespan (English)

1 reference

15 August 2017

0 references

1 reference

1 reference

Marc Tatar

8

0 references

Thomas Flatt

object named as

Thomas Flatt

1

0 references

Ruth Lehmann

6

object named as

Ruth Lehmann

1 reference

15 August 2017

Kyung-Jin Min

2

1 reference

15 August 2017

Cecilia D'Alterio

3

1 reference

15 August 2017

Eugenia Villa-Cuesta

4

1 reference

15 August 2017

John Cumbers

5

1 reference

15 August 2017

D Leanne Jones

7

1 reference

15 August 2017

language of work or name

English

0 references

publication date

23 April 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

105

1 reference

15 August 2017

17

1 reference

15 August 2017

6368-6373

1 reference

Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance.

15 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Caenorhabditis elegans EAK-3 inhibits dauer arrest via nonautonomous regulation of nuclear DAF-16/FoxO activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Distinct activities of the germline and somatic reproductive tissues in the regulation of Caenorhabditis elegans' longevity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in Drosophila

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

FOXO and insulin signaling regulate sensitivity of the circadian clock to oxidative stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Brain IRS2 signaling coordinates life span and nutrient homeostasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Reproduction and longevity: secrets revealed by C. elegans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Regulation of germline stem cell proliferation downstream of nutrient sensing

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

The cost of reproduction: the devil in the details

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

From mice to men: insights into the insulin resistance syndromes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Sex and death: what is the connection?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

A misexpression screen reveals effects of bag-of-marbles and TGF beta class signaling on the Drosophila male germ-line stem cell lineage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

A novel syndrome of autosomal-dominant hyperinsulinemic hypoglycemia linked to a mutation in the human insulin receptor gene

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Control of cell number by Drosophila FOXO: downstream and feedback regulation of the insulin receptor pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Age of ovary determines remaining life expectancy in old ovariectomized mice

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Insulin signalling and the regulation of glucose and lipid metabolism

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Germ cell selection in genetic mosaics in Drosophila melanogaster

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

The acid-labile subunit (ALS) of the 150 kDa IGF-binding protein complex: an important but forgotten component of the circulating IGF system.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Quantitative analysis of gene function in the Drosophila embryo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Signals from the reproductive system regulate the lifespan of C. elegans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Identification and behavior of epithelial stem cells in the Drosophila ovary

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Cost of mating in Drosophila melanogaster females is mediated by male accessory gland products

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Female sterile mutations on the second chromosome of Drosophila melanogaster. II. Mutations blocking oogenesis or altering egg morphology

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Germ cell development in Drosophila

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

No extension of lifespan by ablation of germ line in Drosophila.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Role of brain insulin receptor in control of body weight and reproduction

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

A new secreted insect protein belonging to the immunoglobulin superfamily binds insulin and related peptides and inhibits their activities.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

A role for the Drosophila bag-of-marbles protein in the differentiation of cystoblasts from germline stem cells

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

tudor, a gene required for assembly of the germ plasm in Drosophila melanogaster.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Regulation of life-span by germ-line stem cells in Caenorhabditis elegans

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

A delayed wave of death from reproduction in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Steroid control of longevity in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Genetics and cytology of Drosophila subobscura; an extreme example of delay in gene action, causing sterility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Juvenile hormone as a regulator of the trade-off between reproduction and life span in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

A discrete transcriptional silencer in the bam gene determines asymmetric division of the Drosophila germline stem cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Regulation of zygotic gene expression in Drosophila primordial germ cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Insulin regulation of heart function in aging fruit flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

An evolutionarily conserved function of the Drosophila insulin receptor and insulin-like peptides in growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Nutrient-dependent expression of insulin-like peptides from neuroendocrine cells in the CNS contributes to growth regulation in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Ablation of insulin-producing neurons in flies: growth and diabetic phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Drosophila ALS regulates growth and metabolism through functional interaction with insulin-like peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

A nutrient sensor mechanism controls Drosophila growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Ovariectomy and gonadal hormone treatment: effects on insulin-like growth factor-1 receptors in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Localization of an insulin-like peptide in brains of two flies

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Negligible Senescence during Reproductive Dormancy in Drosophila melanogaster

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

Ectopic expression of the Drosophila Bam protein eliminates oogenic germline stem cells.

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

IMP-L2: an essential secreted immunoglobulin family member implicated in neural and ectodermal development in Drosophila

20 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359818

A cost of mating in female fruitflies

20 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0709128105

Juvenile diet restriction and the aging and reproduction of adult Drosophila melanogaster

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18434551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Molecular signals versus the Loi de Balancement

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18434551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinical review 97: Syndromes of severe insulin resistance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18434551

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0709128105

1 reference

15 August 2017

0 references

1 reference

15 August 2017

PubMed publication ID

18434551

1 reference