Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein (Q36653589)

15 August 2017

Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein (English)

1 reference

ubiquitin-proteasome system

15 August 2017

0 references

0 references

1 reference

4

Edward Rockenstein

1 reference

15 August 2017

5

Eliezer Masliah

1 reference

15 August 2017

6

Bradley T Hyman

1 reference

15 August 2017

Darius Ebrahimi-Fakhari

1

1 reference

15 August 2017

Ippolita Cantuti-Castelvetri

2

1 reference

15 August 2017

Zhanyun Fan

3

1 reference

15 August 2017

Pamela J McLean

7

1 reference

15 August 2017

Vivek K Unni

8

1 reference

15 August 2017

language of work or name

English

0 references

publication date

1 October 2011

1 reference

15 August 2017

Journal of Neuroscience

1 reference

15 August 2017

31

1 reference

15 August 2017

41

1 reference

15 August 2017

14508-14520

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3587176/fullTextXML

inferred from PubMed Central ID database lookup

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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28 June 2018

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28 June 2018

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28 June 2018

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20 September 2018

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20 September 2018

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Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

20 September 2018

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Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death.

20 September 2018

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20 September 2018

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20 September 2018

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Alpha-synuclein alters proteasome function, protein synthesis, and stationary phase viability.

20 September 2018

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20 September 2018

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20 September 2018

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20 September 2018

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α-Synuclein Is Degraded by Both Autophagy and the Proteasome

20 September 2018

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Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

20 September 2018

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Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

20 September 2018

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Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.

20 September 2018

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alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

20 September 2018

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Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells

20 September 2018

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Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons

20 September 2018

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Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

20 September 2018

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Collaborative Analysis of α-Synuclein Gene Promoter Variability and Parkinson Disease

20 September 2018

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Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates

4 December 2018

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12 December 2020

alpha-Synuclein protofibrils inhibit 26 S proteasome-mediated protein degradation: understanding the cytotoxicity of protein protofibrils in neurodegenerative disease pathogenesis.

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12 December 2020

Degradation of alpha-synuclein by proteasome

1 reference

12 December 2020

Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease

1 reference

12 December 2020

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells

1 reference

12 December 2020

10.1523/JNEUROSCI.1560-11.2011

Identifiers

DOI

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

21994367

1 reference